Zobrazeno 1 - 10
of 70
pro vyhledávání: '"Carmen D'Angelo"'
Autor:
Sara Iachettini, Irene Terrenato, Manuela Porru, Serena Di Vito, Angela Rizzo, Carmen D’Angelo, Eleonora Petti, Roberto Dinami, Carmen Maresca, Anna Di Benedetto, Aldo Palange, Antonino Mulè, Angela Santoro, Antonella Palazzo, Paola Fuso, Antonella Stoppacciaro, Patrizia Vici, Lorena Filomeno, Francesca Sofia Di Lisa, Teresa Arcuri, Eriseld Krasniqi, Alessandra Fabi, Annamaria Biroccio, Pasquale Zizza
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 43, Iss 1, Pp 1-16 (2024)
Abstract Background Breast Cancer (BC) can be classified, due to its heterogeneity, into multiple subtypes that differ for prognosis and clinical management. Notably, triple negative breast cancer (TNBC) – the most aggressive BC form – is refract
Externí odkaz:
https://doaj.org/article/b5288dd001e444b193813380b0f2304e
Autor:
Elisabetta Valentini, Marta Di Martile, Matteo Brignone, Marica Di Caprio, Isabella Manni, Michela Chiappa, Ilaria Sergio, Martina Chiacchiarini, Chiara Bazzichetto, Fabiana Conciatori, Simona D’Aguanno, Carmen D’Angelo, Rino Ragno, Michelangelo Russillo, Gianni Colotti, Francesco Marchesi, Maria Laura Bellone, Fabrizio Dal Piaz, Maria Pia Felli, Giovanna Damia, Donatella Del Bufalo
Publikováno v:
Cell Death and Disease, Vol 14, Iss 7, Pp 1-13 (2023)
Abstract BH3 mimetics, targeting the Bcl-2 family anti-apoptotic proteins, represent a promising therapeutic opportunity in cancers. ABT-199, the first specific Bcl-2 inhibitor, was approved by FDA for the treatment of several hematological malignanc
Externí odkaz:
https://doaj.org/article/01533b7f59374555895e9c12fb301709
Autor:
Roberto Dinami, Luca Pompili, Eleonora Petti, Manuela Porru, Carmen D'Angelo, Serena Di Vito, Angela Rizzo, Virginia Campani, Giuseppe De Rosa, Alejandra Bruna, Violeta Serra, Miguel Mano, Mauro Giacca, Carlo Leonetti, Gennaro Ciliberto, Madalena Tarsounas, Antonella Stoppacciaro, Stefan Schoeftner, Annamaria Biroccio
Publikováno v:
EMBO Molecular Medicine, Vol 15, Iss 1, Pp n/a-n/a (2023)
Abstract The telomeric repeat‐binding factor 2 (TRF2) is a telomere‐capping protein that plays a key role in the maintenance of telomere structure and function. It is highly expressed in different cancer types, and it contributes to cancer progre
Externí odkaz:
https://doaj.org/article/329d8d14529b400796d6b5c09e60a4e4
Autor:
Chiara Platella, Francesca Ghirga, Domenica Musumeci, Deborah Quaglio, Pasquale Zizza, Sara Iachettini, Carmen D’Angelo, Annamaria Biroccio, Bruno Botta, Mattia Mori, Daniela Montesarchio
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 4, p 4070 (2023)
Aiming to identify highly effective and selective G-quadruplex ligands as anticancer candidates, five natural compounds were investigated here, i.e., the alkaloids Canadine, D-Glaucine and Dicentrine, as well as the flavonoids Deguelin and Millettone
Externí odkaz:
https://doaj.org/article/f256c704cf9a4f91838f48adb6fb81fd
Autor:
Maria Giovanna Scioli, Simona Artuso, Carmen D'Angelo, Manuela Porru, Federico D'Amico, Alessandra Bielli, Pietro Gentile, Valerio Cervelli, Carlo Leonetti, Augusto Orlandi
Publikováno v:
PLoS ONE, Vol 13, Iss 9, p e0203426 (2018)
Breast cancer represents the main malignancy in women and autologous fat grafting is a diffuse procedure in the management of post-surgical breast defects causing patients' psychosocial problems, with high costs for the public health. Recently, benef
Externí odkaz:
https://doaj.org/article/115f1bc36af24782aaf01b7c3d1523e5
Autor:
Karla Stefanny Huertas Vilca, Luis Augusto Durand Azcárate, Luigi Cabos Villa, Maria del Carmen D'Angelo Panizo
Publikováno v:
Encuentros, Iss 15 (2022)
El artículo tiene por objetivo analizar el sistema educativo peruano a través del contexto de pandemia remarcando la influencia del modelo económico neoliberal en las políticas planteadas frente a la emergencia sanitaria. Es por ello, la necesida
Externí odkaz:
https://doaj.org/article/713bfc9dae224556ab5f29f5ccfc180a
Autor:
Carlo Leonetti, Franco Zunino, Claudio Pisano, Gabriella Zupi, Giovanni Beretta, Eric Gilson, Malcolm F.G. Stevens, Marco Franceschin, Daniela Passeri, Augusto Orlandi, Carmen D'Angelo, Erica Salvati, Angela Rizzo, Manuela Porru, Annamaria Biroccio
Supplementary Table S1.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c7f047f016e298778b7e25575b1ac94
https://doi.org/10.1158/1078-0432.22442592.v1
https://doi.org/10.1158/1078-0432.22442592.v1
Autor:
Carlo Leonetti, Franco Zunino, Claudio Pisano, Gabriella Zupi, Giovanni Beretta, Eric Gilson, Malcolm F.G. Stevens, Marco Franceschin, Daniela Passeri, Augusto Orlandi, Carmen D'Angelo, Erica Salvati, Angela Rizzo, Manuela Porru, Annamaria Biroccio
Purpose: We previously reported that the G-quadruplex (G4) ligand RHPS4 potentiates the antitumor activity of camptothecins both in vitro and in tumor xenografts. The present study aims at investigating the mechanisms involved in this specific drug i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::72b30813e7f09b3f9e8aa8a552918a5d
https://doi.org/10.1158/1078-0432.c.6519282
https://doi.org/10.1158/1078-0432.c.6519282
Autor:
Elisabetta Valentini, Marta Di Martile, Matteo Brignone, Marica Di Caprio, Isabella Manni, Michela Chiappa, Ilaria Sergio, Martina Chiacchiarini, Chiara Bazzichetto, Fabiana Conciatori, Simona D'Aguanno, Carmen D'Angelo, Rino Ragno, Michelangelo Russillo, Gianni Colotti, Maria Felli, Giovanna Damia, Donatella Del Bufalo
BH3 mimetics, targeting Bcl-2 family anti-apoptotic proteins, represent a promising therapeutic opportunity in tumors. ABT-199, the first specific Bcl-2 inhibitor, has been approved by FDA for treating several hematological malignancies. We have rece
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d514d4c3657a153c6895f6d66bf17c55
https://doi.org/10.21203/rs.3.rs-2492502/v1
https://doi.org/10.21203/rs.3.rs-2492502/v1
Autor:
Paola Ostano, Erica Salvati, Chiara Cingolani, Isabella Sperduti, Eleonora Petti, Roberto Dinami, Annamaria Biroccio, Giovanna Chiorino, Marcella Mottolese, Carmen D'Angelo, Giovanni Blandino, Eric Gilson, Manuela Porru, Carla Azzurra Amoreo, Angela Maria Rizzo, Pasquale Zizza, Rosita Russo, Angela Chambery, Carlo Leonetti, Julien Cherfils-Vicini, Andrea Sacconi
Publikováno v:
Nucleic Acids Research
Nucleic Acids Research, 2019
Nucleic Acids Research, Oxford University Press, 2019
HAL
Nucleic Acids Research, 2019
Nucleic Acids Research, Oxford University Press, 2019
HAL
The telomeric protein TRF2 is overexpressed in several human malignancies and contributes to tumorigenesis even though the molecular mechanism is not completely understood. By using a high-throughput approach based on the multiplexed Luminex X-MAP te