Trichinella spiralis Excretory–Secretory Products Induce Tolerogenic Properties in Human Dendritic Cells via Toll-Like Receptors 2 and 4

Autor: Nataša Ilic, Alisa Gruden-Movsesijan, Jelena Cvetkovic, Sergej Tomic, Dragana Bozidar Vucevic, Carmen Aranzamendi, Miodrag Colic, Elena Pinelli, Ljiljana Sofronic-Milosavljevic

Publikováno v: Frontiers in Immunology, Vol 9 (2018)

Trichinella spiralis, as well as its muscle larvae excretory–secretory products (ES L1), given either alone or via dendritic cells (DCs), induce a tolerogenic immune microenvironment in inbred rodents and successfully ameliorate experimental autoim

Externí odkaz: https://doaj.org/article/9fce5ca2a17d4b9083c412e0ef710f17

Helminths: Immunoregulation and Inflammatory Diseases—Which Side Are Trichinella spp. and Toxocara spp. on?

Autor: Carmen Aranzamendi, Ljiljana Sofronic-Milosavljevic, Elena Pinelli

Publikováno v: Journal of Parasitology Research, Vol 2013 (2013)

Macropathogens, such as multicellular helminths, are considered masters of immunoregulation due to their ability to escape host defense and establish chronic infections. Molecular crosstalk between the host and the parasite starts immediately after t

Externí odkaz: https://doaj.org/article/e62e6a17a1914bba90044edd5a337a53

Trichinella spiralis-secreted products modulate DC functionality and expand regulatory T cells in vitro

Autor: Victor P.M.G. Rutten, M. Langelaar, J. P. M. van Putten, Frits Franssen, Carmen Aranzamendi, Elena Pinelli, Floris Fransen, P. Van Der Ley

Publikováno v: Parasite Immunology. 34:210-223

Helminths and their products can suppress the host immune response which may benefit parasite survival. Trichinella spiralis can establish chronic infections in a wide range of mammalian hosts including humans and mice. Here, we aim at studying the e

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::b37468993bda1e476a2790f6cff54574
https://doi.org/10.1111/j.1365-3024.2012.01353.x

Glycan microarray profiling of parasite infection sera identifies the LDNF glycan as a potential antigen for serodiagnosis of trichinellosis

Autor: Irma van Die, Titia Kortbeek, Elena Pinelli, Fabrizio Bruschi, Richard D. Cummings, Lorena Chiumiento, Carmen Aranzamendi, David F. Smith, Boris Tefsen, Montse Jansen

Publikováno v: Experimental Parasitology, 129(3), 221-226. Academic Press Inc.
Aranzamendi, C, Tefsen, B, Jansen, M, Chiumiento, L, Bruschi, F, Kortbeek, T, Smith, D F, Cummings, RD, Pinelli, E & van Die, I M 2011, ' Glycan microarray profiling of parasite infection sera identifies the LDNF glycan as a potential antigen for serodiagnosis of trichinellosis ', Experimental Parasitology, vol. 129, no. 3, pp. 221-226 . https://doi.org/10.1016/j.exppara.2011.08.015

Diagnostic methods for parasite infections still highly depend on the identification of the parasites by direct methods such as microscopic examination of blood, stool and tissue biopsies. Serodiagnosis is often carried out to complement the direct m

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c3508aa8af35d1730b3075851323d81
https://pubmed.ncbi.nlm.nih.gov/21893057

Can microbiota modulation prevent the development of fatty liver disease?

Autor: Anja Wellejus, Diego Garcia de la Morena, Johnson Lok, Silvia Lopez-Escalera, Maria Victoria Fernandez-Cantos, Mohan Babu, Carmen Aranzamendi Esteban, Sahar El Aidy, Kati Hanhineva, Hani El-Nezamy, Oscar Kuipers

Publikováno v: The Project Repository Journal. 14(1):66-69

Can microbiota modulation prevent the development of fatty liver disease? The work described in this article is part of the Marie Skłodowska-Curie Innovative Training Network “Building a Gut Microbiome Engineering Toolbox for In-Situ Therapeutic T

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e4213ae8dd28b5cba88b31dcfd5b460