Supplementary Figure 2 from The ARF Tumor Suppressor Can Promote the Progression of Some Tumors

Autor: Maureen E. Murphy, Christine M. Eischen, Darren J. Burgess, Carmen Dominguez-Brauer, Michal Jarnik, Jack T. Zilfou, Julia Pimkina, Olivier Humbey

Supplementary Figure 2 from The ARF Tumor Suppressor Can Promote the Progression of Some Tumors

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3adfb0be5c23632068ba374d6cf74fb5
https://doi.org/10.1158/0008-5472.22375916

Choline acetyltransferase–expressing T cells are required to control chronic viral infection

Autor: Lisa X. Yu, Alisha R. Elford, Brian J. Nieman, Kevin J. Tracey, Carmen Dominguez-Brauer, Pamela S. Ohashi, Peder S. Olofsson, Maureen A. Cox, Kyle T. Gill, Gordon Duncan, Gloria H. Y. Lin, Jillian Haight, Dirk Brenner, Tak W. Mak, Benjamin E. Steinberg, Shawn P. Kubli, Andrew J. Elia, Thorsten Berger, Luke N. Buckler, Andrew Wakeham

Publikováno v: Cox, M A, Duncan, G S, Lin, G H Y, Steinberg, B E, Yu, L X, Brenner, D, Buckler, L N, Elia, A J, Wakeham, A C, Nieman, B, Dominguez-Brauer, C, Elford, A R, Gill, K T, Kubli, S P, Haight, J, Berger, T, Ohashi, P S, Tracey, K J, Olofsson, P S & Mak, T W 2019, ' Choline acetyltransferase–expressing T cells are required to control chronic viral infection ', Science, vol. 363, no. 6427, pp. 639-644 . https://doi.org/10.1126/science.aau9072

ChAT-ty T cells fight viral infection The neurotransmitter acetylcholine (ACh) is involved in processes such as muscle contraction, neuron communication, and vasodilation. Along with neurons, a population of immunological T cells and B cells express

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5043317ac15000a6e370996f0f3b4f5c
https://doi.org/10.1126/science.aau9072

Idh1 mutations contribute to the development of T-cell malignancies in genetically engineered mice

Autor: Rob A. Cairns, Yi Sheng, Tak W. Mak, Erica Tobin, Jing Ye, Carmen Dominguez-Brauer, Rohini Narayanaswamy, Kimberly Straley, Wanda Y. Li, Dana M. Larsen, François Lemonnier, Satoshi Inoue, Philippe Gaulard, Andrew Wakeham, Zhenyue Hao, Bryan E. Snow

Publikováno v: Proceedings of the National Academy of Sciences. 113:1387-1392

Gain-of-function mutations in isocitrate dehydrogenase 1 (IDH1) are key drivers of hematopoietic malignancies. Although these mutations are most commonly associated with myeloid diseases, they also occur in malignancies of the T-cell lineage. To inve

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6719bc5c07b09dbdc858148ff023f45f
https://doi.org/10.1073/pnas.1525354113

Retraction for Roy et al., 'DDB2, an Essential Mediator of Premature Senescence'

Autor: Srilata Bagchi, Nilotpal Roy, Carmen Dominguez-Brauer, Hyun Jung Park, Tanya Stoyanova, Pradip Raychaudhuri

Publikováno v: Molecular and Cellular Biology. 37

Reactive oxygen species (ROS) is critical for premature senescence, a process significant in tumor suppression and cancer therapy. Here, we reveal a novel function of the nucleotide excision repair protein DDB2 in the accumulation of ROS in a manner

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f6a10fd9960f3b24ec30b5c755872bbe
https://doi.org/10.1128/mcb.00135-17

Severe bilateral Legg-Calvé-Perthes resolved with pamidronate in combination with casts, physiotherapy and adductor tenotomy: a pictorial essay over 11 years

Autor: Carmen A. Brauer, Seemab Haider, Lindsey Logan, Paivi Miettunen

Publikováno v: BMJ Case Reports

We describe an 11-year prospective clinical and radiologic course of a 6-year-old boy with bilateral Legg-Calvé-Perthes disease, who was treated with intravenous pamidronate (IV-PAM). His baseline radiographs showed grade IV avascular necrosis/Catte

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ceac258d854ef7ade6519c83366e203
https://doi.org/10.1136/bcr-2019-229919