Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Carmen A. Argmann"'
Autor:
Roman Kosoy, Seunghee Kim-Schulze, Adeeb Rahman, Joshua R. Friedman, Ruiqi Huang, Lauren A. Peters, El-ad Amir, Jacqueline Perrigoue, Aleksandar Stojmirovic, Won-min Song, Hao Ke, Ryan Ungaro, Saurabh Mehandru, Judy Cho, Marla Dubinsky, Mark Curran, Carrie Brodmerkel, Eric E. Schadt, Bruce E. Sands, Jean-Frederic Colombel, Andrew Kasarskis, Carmen A. Argmann, Mayte Suárez-Fariñas
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 12, Iss 2, Pp 599-632 (2021)
Background: Inflammatory bowel disease (IBD) is a complex disease with variable presentation, progression, and response to therapies. Current disease classification is based on subjective clinical phenotypes. The peripheral blood immunophenome can re
Externí odkaz:
https://doaj.org/article/ce39650906404858884de64148570f38
Autor:
Ariella T. Cohain, William T. Barrington, Daniel M. Jordan, Noam D. Beckmann, Carmen A. Argmann, Sander M. Houten, Alexander W. Charney, Raili Ermel, Katyayani Sukhavasi, Oscar Franzen, Simon Koplev, Carl Whatling, Gillian M. Belbin, Jialiang Yang, Ke Hao, Eimear E. Kenny, Zhidong Tu, Jun Zhu, Li-Ming Gan, Ron Do, Chiara Giannarelli, Jason C. Kovacic, Arno Ruusalepp, Aldons J. Lusis, Johan L. M. Bjorkegren, Eric E. Schadt
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
Some cholesterol-lowering drugs can increase the risk of type 2 diabetes, but the mechanism behind this is not fully understood. Here the authors show that there is a single genetic regulatory module that influences both cholesterol levels and glucos
Externí odkaz:
https://doaj.org/article/0c2afd1828064aad921b2b15f3e5c1e2
Autor:
Jialiang Yang, Jacob Hagen, Kalyani V. Guntur, Kimaada Allette, Sarah Schuyler, Jyoti Ranjan, Francesca Petralia, Stephane Gesta, Robert Sebra, Milind Mahajan, Bin Zhang, Jun Zhu, Sander Houten, Andrew Kasarskis, Vivek K. Vishnudas, Viatcheslav R. Akmaev, Rangaprasad Sarangarajan, Niven R. Narain, Eric E. Schadt, Carmen A. Argmann, Zhidong Tu
Publikováno v:
BMC Genomics, Vol 18, Iss 1, Pp 1-15 (2017)
Abstract Background Exosomes and other extracellular vesicles (EVs) have emerged as an important mechanism of cell-to-cell communication. However, previous studies either did not fully resolve what genetic materials were shuttled by exosomes or only
Externí odkaz:
https://doaj.org/article/0c940c9ca1524a2aba2cc141c228b9cc
Autor:
Sander M. Houten, Simone Denis, Carmen A. Argmann, Yuzhi Jia, Sacha Ferdinandusse, Janardan K. Reddy, Ronald J.A. Wanders
Publikováno v:
Journal of Lipid Research, Vol 53, Iss 7, Pp 1296-1303 (2012)
L-bifunctional enzyme (Ehhadh) is part of the classical peroxisomal fatty acid β-oxidation pathway. This pathway is highly inducible via peroxisome proliferator-activated receptor α (PPARα) activation. However, no specific substrates or functions
Externí odkaz:
https://doaj.org/article/b68d487ec0bf4cc59b2c3909a54bbd9f
Autor:
Stewart C. Whitman, Carmen A. Argmann, Cynthia G. Sawyez, David B. Miller, Robert A. Hegele, Murray W. Huff
Publikováno v:
Journal of Lipid Research, Vol 40, Iss 6, Pp 1017-1028 (1999)
Hypertriglyceridemic (HTG) very low density lipoproteins (VLDL) from subjects with type IV hyperlipoproteinemia induce both cholesteryl ester (CE) and triglyceride (TG) accumulation in cultured J774 macrophages. We examined whether the cytokine inter
Externí odkaz:
https://doaj.org/article/612917d74fa4488d9d6051e74503c46d
Autor:
Ruixue Hou, Ryan C. Ungaro, Haritz Irizar, Marla C. Dubinsky, Jean Frederic Colombel, Carmen A. Argmann, Mayte Suarez-Farinas
Publikováno v:
Gastroenterology. 162:S-611
Autor:
Carmen A, Argmann, Jane Y, Edwards, Cynthia G, Sawyez, Caroline H, O'Neil, Robert A, Hegele, J Geoffrey, Pickering, Murray W, Huff
Publikováno v:
The Journal of biological chemistry. 280(23)
The cholesterol biosynthetic pathway produces numerous signaling molecules. Oxysterols through liver X receptor (LXR) activation regulate cholesterol efflux, whereas the non-sterol mevalonate metabolite, geranylgeranyl pyrophosphate (GGPP), was recen
Autor:
Murray W. Huff, Robert A. Hegele, Carmen A. Argmann, Shaohua Li, J. Geoffrey Pickering, Cynthia G. Sawyez
Publikováno v:
Cardiovascular Pathology. 13:157
Autor:
Wouter Wegdam, Carmen A Argmann, Gertjan Kramer, Johannes P Vissers, Marrije R Buist, Gemma G Kenter, Johannes M F G Aerts, Danielle Meijer, Perry D Moerland
Publikováno v:
PLoS ONE, Vol 9, Iss 9, p e108046 (2014)
PurposeTo identify proteins and (molecular/biological) pathways associated with differences between benign and malignant epithelial ovarian tumors.Experimental proceduresSerum of six patients with a serous adenocarcinoma of the ovary was collected be
Externí odkaz:
https://doaj.org/article/034990b2eb1c49cca4433dc419d364d4