Zobrazeno 1 - 10
of 170
pro vyhledávání: '"Carmen A Mannella"'
Autor:
Maura Greiser, Mariusz Karbowski, Aaron David Kaplan, Andrew Kyle Coleman, Nicolas Verhoeven, Carmen A Mannella, W Jonathan Lederer, Liron Boyman
Publikováno v:
eLife, Vol 12 (2023)
Mitochondrial ATP production in ventricular cardiomyocytes must be continually adjusted to rapidly replenish the ATP consumed by the working heart. Two systems are known to be critical in this regulation: mitochondrial matrix Ca2+ ([Ca2+]m) and blood
Externí odkaz:
https://doaj.org/article/165b4639279f459893cd06a93cbac943
Autor:
Takayuki Kanazawa, Mauro D Zappaterra, Ayako Hasegawa, Ashley P Wright, Erin D Newman-Smith, Karolyn F Buttle, Kent McDonald, Carmen A Mannella, Alexander M van der Bliek
Publikováno v:
PLoS Genetics, Vol 4, Iss 2, p e1000022 (2008)
The C. elegans eat-3 gene encodes a mitochondrial dynamin family member homologous to Opa1 in humans and Mgm1 in yeast. We find that mutations in the C. elegans eat-3 locus cause mitochondria to fragment in agreement with the mutant phenotypes observ
Externí odkaz:
https://doaj.org/article/a009548353de4a6f95308464f4a45af9
Publikováno v:
Current Research in Physiology, Vol 4, Iss , Pp 163-176 (2021)
Folding of the mitochondrial inner membrane (IM) into cristae greatly increases the ATP-generating surface area, SIM, per unit volume but also creates diffusional bottlenecks that could limit reaction rates inside mitochondria. This study explores po
Externí odkaz:
https://doaj.org/article/0d950773c2b040f1963c58c53b9e36bb
Autor:
Keertana Yalamanchili, Nasrin Afzal, Liron Boyman, Carmen A. Mannella, W. Jonathan Lederer, M. Saleet Jafri
Publikováno v:
Membranes, Vol 12, Iss 5, p 494 (2022)
The mitochondrial permeability transition pore (mPTP) is a non-selective pore in the inner mitochondrial membrane (IMM) which causes depolarization when it opens under conditions of oxidative stress and high concentrations of Ca2+. In this study, a s
Externí odkaz:
https://doaj.org/article/6b1e4df73dcb404b9f913922d3c64a1d
Autor:
Maura Greiser, Mariusz Karbowski, Aaron D. Kaplan, Andrew K. Coleman, Carmen A. Mannella, W. J. Lederer, Liron Boyman
Mitochondrial ATP production in cardiac ventricular myocytes must be continually adjusted to rapidly replenish the ATP consumed by the working heart. Two systems are known to be critical in this regulation: mitochondrial matrix Ca2+([Ca2+]m) and bloo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9d016d5312f13fc3f9d2cba9d1bc8dec
https://doi.org/10.1101/2022.10.31.514581
https://doi.org/10.1101/2022.10.31.514581
Publikováno v:
Current Research in Physiology, Vol 4, Iss, Pp 163-176 (2021)
Current research in physiology
Current research in physiology
Folding of the mitochondrial inner membrane (IM) into cristae greatly increases the ATP-generating surface area, SIM, per unit volume but also creates diffusional bottlenecks that could limit reaction rates inside mitochondria. This study explores po
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cfa593333772dbaceb9b81225f01ca80
http://www.sciencedirect.com/science/article/pii/S2665944121000146
http://www.sciencedirect.com/science/article/pii/S2665944121000146
Autor:
Maura Greiser, Mariusz Karbowski, Aaron D. Kaplan, Andrew Coleman, Carmen A. Mannella, W. Jonathan Lederer, Liron Boyman
Publikováno v:
Biophysical Journal. 122:94a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a5c5b2c58cc930e26b0863e7fc05dd90
https://doi.org/10.1016/j.bpj.2022.11.703
https://doi.org/10.1016/j.bpj.2022.11.703
Autor:
Carmen A. Mannella
Publikováno v:
Frontiers in Physiology
Frontiers in Physiology, Vol 11 (2020)
Frontiers in Physiology, Vol 11 (2020)
A fundamental first step in the evolution of eukaryotes was infolding of the chemiosmotic membrane of the endosymbiont. This allowed the proto-eukaryote to amplify ATP generation while constraining the volume dedicated to energy production. In mitoch
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::36f2f102cee1e27d0ca88e121fc1e862
https://doi.org/10.3389/fphys.2020.00536
https://doi.org/10.3389/fphys.2020.00536
Autor:
Carmen A. Mannella
Publikováno v:
Biophysical Journal. 121:511a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4d110146e69e1b594b7e24c193bdcd01
https://doi.org/10.1016/j.bpj.2021.11.235
https://doi.org/10.1016/j.bpj.2021.11.235
Autor:
Liron Boyman, Christopher W. Ward, Carmen A. Mannella, W. Jonathan Lederer, Andrew K. Coleman
Publikováno v:
Biophysical Journal. 120:347a-348a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ec0b13d7fb82bfd21929c716838540ee
https://doi.org/10.1016/j.bpj.2020.11.2163
https://doi.org/10.1016/j.bpj.2020.11.2163