Association analysis in a Latin American population revealed ethnic differences in rheumatoid arthritis-associated SNPs in Caucasian and Asian populations

Autor: Alejandro Lucia, Carmen Pinochet, José Suazo, Rebeca Alonso-Arias, Roberto Díaz-Peña, Jordi Olloquequi, Juan Carlos Aguillón, Luis A. Quiñones, Patricia Castro-Santos, M A Gutiérrez, Ricardo A. Verdugo

Publikováno v: Scientific Reports, Vol 10, Iss 1, Pp 1-7 (2020)
Dipòsit Digital de la UB
Universidad de Barcelona
Scientific Reports
ABACUS. Repositorio de Producción Científica
Universidad Europea (UEM)

Large genome-wide association studies (GWAS) have increased our knowledge of the genetic risk factors of rheumatoid arthritis (RA). However, little is known about genetic susceptibility in populations with a large admixture of Amerindian ancestry. Th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::70dd8fd658046f74cf0f8f7fd60402cf
http://link.springer.com/article/10.1038/s41598-020-64659-0

Prevalence of antiphospholipid antibodies in Chilean patients with rheumatoid arthritis

Autor: Ricardo Forastiero, Marcelo Alarcón, Jaime Gonzalez, Iván Palomo, Carmen Pinochet, Francisco Monsalves, Rodrigo Sandoval

Antiphospholipid (aPL) antibodies found in patients with autoimmune diseases are also detected in those with inflammatory diseases. The purpose of this study was to examine the prevalence of these antibodies in patients with rheumatoid arthritis (RA)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::590c9bbdef8719e72de2f00844f12ad7
https://europepmc.org/articles/PMC6807502/

Val/Leu247 and Trp/Ser316 polymorphisms in beta 2 glycoprotein I and their association with thrombosis in unselected Chilean patients

Autor: Iván Palomo, Jeannette Sandoval, Evelyn Mendez, Fernando Poblete, Rolando Vidal, Marcela Vásquez, Jaime Pereira, Silvia S. Pierangeli, Marcelo Alarcón, Carmen Pinochet

Publikováno v: Clinical rheumatology. 26(3)

It is known that polymorphisms of β 2-glycoprotein I (β 2GPI) in exon 7 affect interaction between the phospholipid binding site and the antibodies, and that other polymorphisms in exon 8 increase the generation of antibodies. In this study, we ana

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c2ac8f1cdfd6bff8ce5ad78265398a6c
https://pubmed.ncbi.nlm.nih.gov/16724168

Prevalence and isotype distribution of antiphospholipid antibodies in unselected Chilean patients with venous and arterial thrombosis

Autor: Jaime Pereira, Maria T. Velez, Gloria Icaza, Marcelo Alarcón, Iván Palomo, Carmen Pinochet, Marcela Vásquez, Jorge Sandoval, Silvia S. Pierangeli

Publikováno v: Clinical rheumatology. 23(2)

Antiphospholipid antibodies (aPL) are a heterogeneous family of antibodies associated with thrombotic events and other complications. The objective of this study was to investigate the prevalence of aPL in a group of Chilean patients with thrombosis.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ebaef7117d2d1e1ec627827bfbe95dc
https://pubmed.ncbi.nlm.nih.gov/15045627

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