Generation of a Soluble Form of Human Endoglin Fused to Green Fluorescent Protein

Autor: Paul D. Upton, Francisco J. Fernández, Carmen Langa, M. Cristina Vega, Nicholas W. Morrell, Lidia Ruiz-Llorente, Carmelo Bernabeu

Publikováno v: International Journal of Molecular Sciences
Digital.CSIC. Repositorio Institucional del CSIC
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International Journal of Molecular Sciences, Vol 22, Iss 11282, p 11282 (2021)
Volume 22
Issue 20

13 p.-5 fig.
Endoglin (Eng, CD105) is a type I membrane glycoprotein that functions in endothelial cells as an auxiliary receptor for transforming growth factor β (TGF-β)/bone morphogenetic protein (BMP) family members and as an integrin ligan

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a9d8d1aa1a90a7a97ecfceb27af3d0a

Heterozygous deficiency of endoglin decreases insulin and hepatic triglyceride levels during high fat diet.

Autor: Daniel Beiroa, Amparo Romero-Picó, Carmen Langa, Carmelo Bernabeu, Miguel López, José M López-Novoa, Ruben Nogueiras, Carlos Diéguez

Publikováno v: PLoS ONE, Vol 8, Iss 1, p e54591 (2013)

Endoglin is a transmembrane auxiliary receptor for transforming growth factor-beta (TGF-beta) that is predominantly expressed on proliferating endothelial cells. It plays a wide range of physiological roles but its importance on energy balance or ins

Externí odkaz: https://doaj.org/article/18d2ad14aec3418aaa67101302935b79

Functional analysis of a novel ENG variant in a patient with Hereditary Hemorrhagic Telangiectasia (HHT) identifies a new Sp1 binding-site

Autor: Donata Cappelletti, Alessandra Greco, Jacopo Morini, Carmelo Bernabeu, Lidia Ruiz-Llorente, Sara Plumitallo, Carmen Langa, Gabriele Babini, Cesare Danesino, Laura Scelsi, Carla Olivieri

Publikováno v: Digital.CSIC. Repositorio Institucional del CSIC
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19 p.-6 fig. Plumitallo. Sara et al.
Hereditary Hemorrhagic Telangiectasia (HHT) is a rare disease, with an autosomal dominant inheritance and a worldwide incidence of about 1: 5000 individuals. In >80% of patients, HHT is caused by mutations in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b1e403426a7f1bc4e572ad02e7f17950
http://hdl.handle.net/10261/160767

Endothelial endoglin is involved in inflammation: role in leukocyte adhesion and transmigration

Autor: Francisco J. Blanco, Carmen Langa, Luisa María Botella, José M. López-Novoa, Carmelo Bernabeu, Francisco Sanz-Rodríguez, Elisa Rossi, Carlos Cabañas, Nélida Eleno, Annette Düwell

Publikováno v: ResearcherID
Digital.CSIC. Repositorio Institucional del CSIC
instname

Human endoglin is an RGD-containing transmembrane glycoprotein identified in vascular endothelial cells. Although endoglin is essential for angiogenesis and its expression is up-regulated in inflammation and at sites of leukocyte extravasation, its r

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b5fd80fd20f8856c7dd8c9dc456e9c7
https://doi.org/10.1182/blood-2012-06-435347

0260 : Endoglin in adhesion between endothelial and mural cells

Autor: Pascale Gaussem, Miguel Arévalo, Joyce Bischoff, Miguel Pericacho, Elisa Boscolo, David M. Smadja, Carmelo Bernabeu, Elisa Rossi, Luisa María Botella, Jose-Miguel López-Novoa, Carmen Langa, Alexandre Kauskot

Publikováno v: Archives of Cardiovascular Diseases Supplements. 7(2)

The interaction and interplay between endothelial cells (ECs) and mural cells (such as vascular smooth muscle cells -VSMCs- and pericytes) play a pivotal role in vascular biology. Endoglin is an RGD-containing ligand of β1 integrins highly expressed

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::033b0e7709ee0d486f5ec05709abb5fb