Zobrazeno 1 - 10
of 189
pro vyhledávání: '"Carmen, Berasain"'
Autor:
Miguel Sogbe, Idoia Bilbao, Francesco P. Marchese, Jon Zazpe, Annarosaria De Vito, Marta Pozuelo, Delia D’Avola, Mercedes Iñarrairaegui, Carmen Berasain, Maria Arechederra, Josepmaria Argemi, Bruno Sangro
Publikováno v:
Clinical and Molecular Hepatology, Vol 30, Iss 2, Pp 177-190 (2024)
Background/Aims New prognostic markers are needed to identify patients with hepatocellular carcinoma (HCC) who carry a worse prognosis. Ultra-low-pass whole-genome sequencing (ULP-WGS) (≤0.5× coverage) of cell-free DNA (cfDNA) has emerged as a low
Externí odkaz:
https://doaj.org/article/208518fea3204466ae05f9ee501d23d6
Autor:
Carla Rojo, María Gárate-Rascón, Miriam Recalde, Ane Álava, María Elizalde, María Azkona, Iratxe Aldabe, Elisabet Guruceaga, Amaya López-Pascual, M Ujue Latasa, Bruno Sangro, Maite G. Fernández-Barrena, Matías A. Ávila, María Arechederra, Carmen Berasain
Publikováno v:
JHEP Reports, Vol 6, Iss 8, Pp 101118- (2024)
Background & Aims: The homeostasis of the cellular transcriptome depends on transcription and splicing mechanisms. Moreover, the fidelity of gene expression, essential to preserve cellular identity and function is secured by different quality control
Externí odkaz:
https://doaj.org/article/839678c118424464b7ef2ce1b0908674
Autor:
Maria Arechederra, Maria Rullán, Daniel Oyón, Matias A. Ávila, Jesús M. Urman, Carmen Berasain
Publikováno v:
Exploration of Digestive Diseases, Vol 3, Iss 1, Pp 5-21 (2024)
Hunting for tumoral material in body fluids, traditionally in blood, the so-called liquid biopsy is set to revolutionize the diagnosis and management of oncological patients. However, other biofluids can also be considered as alternative sources of b
Externí odkaz:
https://doaj.org/article/09fd70e8623344b0845f7f6c5c210d6b
Autor:
Amaya Lopez-Pascual, Marc Cusachs, María Arechederra, Carmen Berasain, Matías A. Ávila, Maite G. Fernández-Barrena
Publikováno v:
Exploration of Digestive Diseases, Vol 1, Iss 2, Pp 80-96 (2022)
Caspases are key factors in the regulation of the apoptotic and/or inflammatory responses, both crucial in the pathogenesis of diverse diseases. Caspase-2 is the most evolutionary conserved albeit functionally poorly defined member of the caspase fam
Externí odkaz:
https://doaj.org/article/d92e9ff5315d42238b0b96d2e9861c93
Autor:
Leticia Colyn, Gloria Alvarez-Sola, M. Ujue Latasa, Iker Uriarte, Jose M. Herranz, Maria Arechederra, George Vlachogiannis, Colin Rae, Antonio Pineda-Lucena, Andrea Casadei-Gardini, Federica Pedica, Luca Aldrighetti, Angeles López-López, Angeles López-Gonzálvez, Coral Barbas, Sergio Ciordia, Sebastiaan M. Van Liempd, Juan M. Falcón-Pérez, Jesus Urman, Bruno Sangro, Silve Vicent, Maria J. Iraburu, Felipe Prosper, Leonard J. Nelson, Jesus M. Banales, Maria Luz Martinez-Chantar, Jose J. G. Marin, Chiara Braconi, Christian Trautwein, Fernando J. Corrales, F. Javier Cubero, Carmen Berasain, Maite G. Fernandez-Barrena, Matias A. Avila
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 41, Iss 1, Pp 1-18 (2022)
Abstract Background Cholangiocarcinoma (CCA) is still a deadly tumour. Histological and molecular aspects of thioacetamide (TAA)-induced intrahepatic CCA (iCCA) in rats mimic those of human iCCA. Carcinogenic changes and therapeutic vulnerabilities i
Externí odkaz:
https://doaj.org/article/278c7dac66c24c988487ac905912005b
Autor:
María Páramo, Eva Santamaría, Miguel A. Idoate, Macarena Rodríguez-Fraile, Alberto Benito, Maria Collantes, Gemma Quincoces, Iván Peñuelas, Carmen Berasain, Josepmaria Argemi, Jorge Quiroga, Bruno Sangro, José I. Bilbao, Mercedes Iñarrairaegui
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-12 (2022)
Abstract Lobar selective internal radiation therapy (SIRT) is widely used to treat liver tumors inducing atrophy of the treated lobe and contralateral hypertrophy. The lack of animal model has precluded further investigations to improve this treatmen
Externí odkaz:
https://doaj.org/article/9b8adb35808e471683505cf5bacd215d
Autor:
Josepmaria Argemi, Maria U. Latasa, Stephen R. Atkinson, Ilya O. Blokhin, Veronica Massey, Joel P. Gue, Joaquin Cabezas, Juan J. Lozano, Derek Van Booven, Aaron Bell, Sheng Cao, Lawrence A. Vernetti, Juan P. Arab, Meritxell Ventura-Cots, Lia R. Edmunds, Constantino Fondevila, Peter Stärkel, Laurent Dubuquoy, Alexandre Louvet, Gemma Odena, Juan L. Gomez, Tomas Aragon, Jose Altamirano, Juan Caballeria, Michael J. Jurczak, D. Lansing Taylor, Carmen Berasain, Claes Wahlestedt, Satdarshan P. Monga, Marsha Y. Morgan, Pau Sancho-Bru, Philippe Mathurin, Shinji Furuya, Carolin Lackner, Ivan Rusyn, Vijay H. Shah, Mark R. Thursz, Jelena Mann, Matias A. Avila, Ramon Bataller
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-1 (2023)
Externí odkaz:
https://doaj.org/article/65a267dd546740ec9b7190c3e67982ab
Autor:
María Gárate-Rascón, Miriam Recalde, Carla Rojo, Maite G. Fernández-Barrena, Matías A. Ávila, María Arechederra, Carmen Berasain
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 21, p 13411 (2022)
SLU7 (Splicing factor synergistic lethal with U5 snRNA 7) was first identified as a splicing factor necessary for the correct selection of 3′ splice sites, strongly impacting on the diversity of gene transcripts in a cell. More recent studies have
Externí odkaz:
https://doaj.org/article/baa076ee88a54570b82ca350d497856b
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 11, Iss 1, Pp 291-293 (2021)
Externí odkaz:
https://doaj.org/article/11c2a4d1b4974f598e754528afd878e0
Autor:
Allen T Yu, Carmen Berasain, Sonam Bhatia, Keith Rivera, Bodu Liu, Frank Rigo, Darryl J Pappin, David L Spector
Publikováno v:
eLife, Vol 10 (2021)
Hepatocellular carcinoma, the most common type of liver malignancy, is one of the most lethal forms of cancer. We identified a long non-coding RNA, Gm19705, that is overexpressed in hepatocellular carcinoma and mouse embryonic stem cells. We named th
Externí odkaz:
https://doaj.org/article/72f24e0d4ca04037b061615c66b60f36