Improved collection of hematopoietic stem cells and progenitors from Fanconi anemia patients for gene therapy purposes

Autor: Julián Sevilla, Susana Navarro, Paula Rio, Rebeca Sánchez-Domínguez, Josune Zubicaray, Eva Gálvez, Eva Merino, Elena Sebastián, Carmen Azqueta, José A. Casado, José C. Segovia, Omaira Alberquilla, Massimo Bogliolo, Francisco J. Román-Rodríguez, Yari Giménez, Lise Larcher, Rocío Salgado, Roser M. Pujol, Raquel Hladun, Ana Castillo, Jean Soulier, Sergi Querol, Jesús Fernández, Jonathan Schwartz, Nagore García de Andoín, Ricardo López, Albert Catalá, Jordi Surralles, Cristina Díaz-de-Heredia, Juan A. Bueren

Publikováno v: Molecular Therapy: Methods & Clinical Development, Vol 22, Iss , Pp 66-75 (2021)

Difficulties in the collection of hematopoietic stem and progenitor cells (HSPCs) from Fanconi anemia (FA) patients have limited the gene therapy in this disease. We have investigated (ClinicalTrials.gov, NCT02931071) the safety and efficacy of filgr

Externí odkaz: https://doaj.org/article/ff619351134c4b8d89b9a48f91e2e8e9

A hub-and-spoke model to deliver effective access to chimeric antigen receptor T-cell therapy in a public health network: the Catalan Blood and Tissue Bank experience

Autor: Jesus Fernandez-Sojo, Joaquim Delgadillo, Joaquim Vives, Luciano Rodriguez, Ana Mendoza, Carmen Azqueta, Ana Garcia-Buendia, Elena Valdivia, Lluis Martorell, Nuria Rubio-Lopez, Mónica Linares, Sofia Alonso, Agueda Ancochea, Enric García-Rey, Nadia García-Muñoz, Laura Medina, Sergio Querol

Publikováno v: Cytotherapy. 25:14-19

To describe and analyze whether a hub-and-spoke organizational model could efficiently provide access to chimeric antigen receptor (CAR) T-cell therapy within a network of academic hospitals and address the growing demands of this complex and special

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::65585119fd820e266362576f0db062a5
https://doi.org/10.1016/j.jcyt.2022.07.011

Leukocytapheresis variables and transit time for allogeneic cryopreserved hpc: better safe than sorry

Autor: Jesus Fernandez-Sojo, Roger Horton, Joan Cid, Carmen Azqueta, Ana Garcia-Buendia, Elena Valdivia, Lluis Martorell, Nuria Rubio-Lopez, Margarita Codinach, Gemma Aran, Julia Marsal, Alberto Mussetti, Rodrigo Martino, Cristina Diaz-de-Heredia, Christelle Ferra, David Valcarcel, Mónica Linares, Agueda Ancochea, Enric García-Rey, Nadia García-Muñoz, Laura Medina, Enric Carreras, Juliana Villa, Miquel Lozano, Daniel Gibson, Sergio Querol

Publikováno v: Bone Marrow Transplantation
r-IGTP. Repositorio Institucional de Producción Científica del Instituto de Investigación Germans Trias i Pujol
instname
BONE MARROW TRANSPLANTATION
r-IIB SANT PAU. Repositorio Institucional de Producción Científica del Instituto de Investigación Biomédica Sant Pau
r-FSJD. Repositorio Institucional de Producción Científica de la Fundació Sant Joan de Déu

Cryopreservation was recommended to ensure continuity in allogeneic hematopoietic progenitor cells (HPC) transplantation during the COVID-19 pandemic. Several groups have shown no impact on clinical outcomes for patients who underwent HPC transplanta

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fbc68cc6a6df2b4e78a8961d500dd09a
https://pubmed.ncbi.nlm.nih.gov/35804055

Cryopreservation of unrelated donor hematopoietic stem cells: the right answer for transplantations during the COVID-19 pandemic?

Autor: Rocío Parody, Christelle Ferra, Laura Medina, Maria Trabazo, Lluís Martorell, Izaskun Elorza, Nerea Castillo, Elena Valdivia, Carmen Azqueta, Juliana Villa, Margarita Codinach, Nadia García-Muñoz, Enric García-Rey, Jesus Fernandez-Sojo, Laura Medina-Boronat, Enric Carreras, Agueda Ancochea, Rodrigo Martino, Silvia Torrents, Sergio Querol, David Valcárcel, Carme Canals, Cristina Díaz de Heredia, Nuria Martínez-Llonch, Mónica Linares

Publikováno v: Bone Marrow Transplantation
r-IGTP. Repositorio Institucional de Producción Científica del Instituto de Investigación Germans Trias i Pujol
instname
Dipòsit Digital de la UB
Universidad de Barcelona
BONE MARROW TRANSPLANTATION
r-IIB SANT PAU. Repositorio Institucional de Producción Científica del Instituto de Investigación Biomédica Sant Pau
Instituto de Salud Carlos III (ISCIII)
r-FSJD: Repositorio Institucional de Producción Científica de la Fundació Sant Joan de Déu
Fundació Sant Joan de Déu
r-FSJD. Repositorio Institucional de Producción Científica de la Fundació Sant Joan de Déu

Cryopreservation was recommended to ensure continuity of unrelated donor (UD) hematopoietic stem cell transplantation (HSCT) during COVID-19 pandemic. However, its impact on clinical outcomes and feasibility was not well known. We compared 32 patient

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e96bf3154601f135cbfbf37da0982b3
https://fundanet.igtp.cat/Publicaciones/ProdCientif/PublicacionFrw.aspx?id=1953

Clinical evaluation of allogeneic eye drops from cord blood platelet lysate

Autor: Dinara, Samarkanova, Sara, Martin, Laia, Bisbe, Javier, Puig, Marta, Calatayud-Pinuaga, Luciano, Rodriguez, Carmen, Azqueta, Ruth, Coll, Ricardo, Casaroli-Marano, Alejandro, Madrigal, Paolo, Rebulla, Sergio, Querol

Publikováno v: Blood Transfus

BACKGROUND: Current treatments for several corneal lesions show limited efficacy. Here we report the clinical evaluation of the efficacy of a novel eye drop preparation produced in a public cord blood (CB) bank. MATERIALS AND METHODS: In a multicentr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::561d1a68f37c1fe368dd8b6c1d390d11
https://pubmed.ncbi.nlm.nih.gov/33085593