Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Carmelo Muià"'
Autor:
Emanuela Esposito, Carmelo Muià, Rosanna Di Paola, Tiziana Genovese, Placido Bramanti, Rosaria Meli, Emanuela Mazzon, Salvatore Cuzzocrea
Publikováno v:
Shock. 30:142-152
Peroxisome proliferator-activated receptor (PPAR) gamma is a member of the nuclear-receptor superfamily that binds to DNA with retinoid X receptors as PPAR-retinoid X receptor heterodimers. Recent evidence also suggests that the cyclopentenone prosta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e10869f3880ed9ba747dc2ae55c5bd1f
https://doi.org/10.1097/shk.0b013e31815dd381
https://doi.org/10.1097/shk.0b013e31815dd381
Autor:
Salvatore Cuzzocrea, Lidia Sautebin, Carmelo Muià, Placido Bramanti, Emanuela Mazzon, R. Di Paola, Antonietta Rossi, Rocco Caminiti, Tiziana Genovese
Publikováno v:
British Journal of Pharmacology. 153:568-582
Background and purpose: 5-lipoxygenase (5-LO) is the key enzyme in leukotriene (LT) biosynthesis from arachidonic acid (AA). Here, we examined the role of the 5-LO-product, cysteinyl-LT (Cys-LT), with a 5-LO inhibitor (zileuton) and a Cys-LT, recepto
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ba4cf4e45a03d12802eb444951c73d93
https://doi.org/10.1038/sj.bjp.0707577
https://doi.org/10.1038/sj.bjp.0707577
Autor:
S. Cuzzocrea, Giacomo Oteri, D Terrana, Domenico Santori, Domenico Britti, Giancarlo Cordasco, Carmelo Muià, S. Greco, Emanuela Mazzon, R. Di Paola, C Crisafulli
Publikováno v:
British Journal of Pharmacology. 150:286-297
Background and purpose: Etanercept is a tumour necrosis factor antagonist with anti-inflammatory effects. The aim of our study was to evaluate, for the first time, the therapeutic efficacy of in vivo inhibition of TNF-α in an experimental model of p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::380b3ffad9dbe651a74d75c6d14d2fc9
https://doi.org/10.1038/sj.bjp.0706979
https://doi.org/10.1038/sj.bjp.0706979
Autor:
Rosaria Meli, Emanuela Mazzon, Carmelo Muià, Salvatore Cuzzocrea, Edoardo Sessa, Emanuela Esposito
Publikováno v:
Journal of Leukocyte Biology. 81:1032-1043
In the present study, we used TNF-α receptor 1 knockout (TNF-αR1KO) mice to evaluate a possible role of TNF-α on the pathogenesis of ischemia and reperfusion injury of the multivisceral organs. Ischemia and reperfusion injury was induced in mice b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::30de15303fc5b4597f8f156639be97d5
https://doi.org/10.1189/jlb.0706480
https://doi.org/10.1189/jlb.0706480
Autor:
Maha Abdelrahman, Emanuela Esposito, Emanuela Mazzon, C. Thiemermann, S. Cuzzocrea, Carmelo Muià, R. Di Paola, C Crisafulli
Publikováno v:
British Journal of Pharmacology. 149:687-702
Background and purpose: Glycogen synthase kinase-3 (GSK-3) is a ubiquitous serine-threonine protein kinase that participates in a multitude of cellular processes and has recently been implicated in the pathophysiology of a number of diseases. The aim
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::86f793c0c236f29ada0e659c220cf8a8
https://doi.org/10.1038/sj.bjp.0706902
https://doi.org/10.1038/sj.bjp.0706902
Autor:
Emanuela Masini, Emanuela Mazzon, Alfredo Vannacci, Salvatore Cuzzocrea, Carmelo Muià, Francesca Fabrizi, Daniele Bani
Publikováno v:
British Journal of Pharmacology. 148:1124-1132
1 Splanchnic artery occlusion (SAO) followed by reperfusion causes endothelial injury and inflammation which contribute to the pathophysiology of shock. We investigated the effects of relaxin (RLX), known to afford protection against the deleterious
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dd32151f1ff625ca14c52c83c776957c
https://doi.org/10.1038/sj.bjp.0706811
https://doi.org/10.1038/sj.bjp.0706811
Autor:
Carmelo Muià, Marta Menegazzi, Rosanna D. I. Paola, Emanuela Mazzon, Concetta Crisafulli, Hisanori Suzuki, Tiziana Genovese, Achille P. Caputi, Salvatore Cuzzocrea
Publikováno v:
Shock. 24:255-263
Oxidative stress results from an oxidant/antioxidant imbalance, an excess of oxidants, and/or a depletion of antioxidants. A considerable body of recent evidence suggests that oxidative stress and exaggerated production of reactive oxygen species pla
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4377ed4feebf4e2671d6d1ba8c6a769a
https://doi.org/10.1097/01.shk.0000175428.57769.34
https://doi.org/10.1097/01.shk.0000175428.57769.34
Autor:
Carmelo Muià, Emanuela Mazzon, Tiziana Genovese, Achille P. Caputi, Rosanna Di Paola, Salvatore Cuzzocrea
Publikováno v:
Journal of Pineal Research. 39:105-112
Melatonin is the principal secretory product of the pineal gland and its role as an immuno-modulator is well established. Recent evidence shows that melatonin is a scavenger of oxyradicals and peroxynitrite and exerts protective effects in septic sho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e360de19db3f5bd82e503d62a3b3d684
https://doi.org/10.1111/j.1600-079x.2005.00229.x
https://doi.org/10.1111/j.1600-079x.2005.00229.x
Autor:
Michael D. Threadgill, Carmelo Muià, Christoph Thiemermann, Nimesh S. A. Patel, Salvatore Cuzzocrea, Tiziana Genovese, Emanuela Mazzon, Placido Bramanti, Angelina De Sarro
Publikováno v:
Journal of Pharmacology and Experimental Therapeutics. 312:449-457
Poly(ADP-ribose) polymerase (PARP), a nuclear enzyme activated by strand breaks in DNA, plays an important role in the tissue injury associated with stroke and neurotrauma. The aim of our study was to evaluate the therapeutic efficacy of in vivo inhi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fae279e8758a7ebdbb5fcb2a97838f36
https://doi.org/10.1124/jpet.104.076711
https://doi.org/10.1124/jpet.104.076711
Autor:
Stefano Bruscoli, Salvatore Cuzzocrea, Concetta Crisafulli, Carlo Riccardi, Carmelo Muià, Massimiliano Agostini, Emanuela Mazzon, Rosaria Meli, Elisabetta Vegeto, Emanuela Esposito, Rosa Di Virgilio, Adriana Maggi
Publikováno v:
Molecular pharmacology. 71(1)
The glucocorticoid receptor (GR) and estrogen receptor (ER) play important roles in both physiological and pathological conditions involving cell growth and differentiation, lipolysis, control of glucose metabolism, immunity, and inflammation. In fac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba5402b714fdab64fb20ed5d0f22fd96
https://pubmed.ncbi.nlm.nih.gov/17035596
https://pubmed.ncbi.nlm.nih.gov/17035596