Zobrazeno 1 - 10
of 81
pro vyhledávání: '"Carmelita G. Frondoza"'
Publikováno v:
Applied In Vitro Toxicology. 7:4-13
Introduction: Evaluation of hepatocyte response to inflammatory and oxidative stress inducing agents has been hampered by limited availability of appropriate in vitro testing methods. There is an u...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6d11e17b5ad9e4b50253fcabdd655e85
https://doi.org/10.1089/aivt.2020.0015
https://doi.org/10.1089/aivt.2020.0015
Autor:
Mark W Grzanna, Lowella V Fortuno, Cathleen A. Mochal-King, Angela Y. Au, Carmelita G. Frondoza, Ann M. Rashmir, Jillian Dougherty
Publikováno v:
VCOT Open. :e16-e24
Objectives The aim of this study was to evaluate the effect of amikacin (AK) and enrofloxacin (EF) at concentrations consistent with those obtained by intra-articular and intravenous regional limb perfusion on both cytotoxicity and prostaglandin E2 (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bf8c1d8f87611fbf04fc7290a24ef4c6
https://doi.org/10.1055/s-0039-1693441
https://doi.org/10.1055/s-0039-1693441
Publikováno v:
Cartilage
Objective Osteoarthritis is a painful, chronic joint disease affecting man and animals with no known curative therapies. Palliative nonsteroidal anti-inflammatory drugs (NSAIDs) are commonly used but they cause adverse side effects prompting the sear
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::491134ba1fdd4e4eea5627ea54c2ae34
https://doi.org/10.1177/1947603518783495
https://doi.org/10.1177/1947603518783495
Publikováno v:
Journal of medicinal food. 23(2)
Tendinopathy, a common disorder in man and horses, is characterized by pain, dysfunction, and tendon degeneration. Inflammation plays a key role in the pathogenesis of tendinopathy. Tendon cells produce proinflammatory molecules that induce pain and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::492517f3bf64e73e71976a263defe714
https://pubmed.ncbi.nlm.nih.gov/31486703
https://pubmed.ncbi.nlm.nih.gov/31486703
Autor:
Lowella V Fortuno, Stacy Ownby, Mark W Grzanna, Angela Y. Au, Carmelita G. Frondoza, Ann M. Rashmir-Raven
Objective Pro-inflammatory mediators such as prostaglandin E-2 (PGE2) play major roles in the pathogenesis of osteoarthritis (OA). Although current pharmacologic treatments reduce inflammation, their prolonged use is associated with deleterious side
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a8fe3c54fd791e6b2dec7f2a7ef9377a
https://europepmc.org/articles/PMC6042030/
https://europepmc.org/articles/PMC6042030/
Publikováno v:
American Journal of Veterinary Research. 74:983-989
Objective—To determine whether oxidative stress could be induced in canine chondrocytes in vitro. Sample—Chondrocytes obtained from healthy adult mixed-breed dogs. Procedures—Harvested chondrocytes were maintained at 37°C with 5% CO2 for 24 ho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::964394404867994246c4314e88eb8f84
https://doi.org/10.2460/ajvr.74.7.983
https://doi.org/10.2460/ajvr.74.7.983
Autor:
Carmelita G. Frondoza, Richard A. Malinauskas, John P. Fisher, Victoria M. Hitchins, Kimberly M. Ferlin, Thomas J. Vegella, David S. Kaplan
Publikováno v:
Tissue Engineering Part C: Methods. 18:537-544
A major obstacle in chondrocyte-based therapy for cartilage repair is the limited availability of cells that maintain their original phenotype. Propagation of chondrocytes as monolayer cultures on polystyrene surfaces is used extensively for amplifyi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8af48a0ae6094bb5bd44a417b7ebbda7
https://doi.org/10.1089/ten.tec.2011.0043
https://doi.org/10.1089/ten.tec.2011.0043
Publikováno v:
Journal of Animal Physiology and Animal Nutrition. 97:331-341
Summary Inflammation and oxidative stress are associated with liver injury and development of liver disease. The transcription factors nuclear factor-kappa beta (NF-κB) and nuclear factor erythroid 2–related factor 2 (Nrf2) play critical roles in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1412a1706fd0bfd8f71c4949ec52656b
https://doi.org/10.1111/j.1439-0396.2012.01275.x
https://doi.org/10.1111/j.1439-0396.2012.01275.x
Publikováno v:
Journal of Biomedical Materials Research Part A. :342-352
Anchorage-dependent cells including hepatocytes, the main functional cellular constituent comprising liver tissue, require a substrate for cell adhesion when cultured outside their native tissue. The challenge with hepatocyte culture is that material
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::70d9d98205f84cd1222b9176a7a2c622
https://doi.org/10.1002/jbm.a.33277
https://doi.org/10.1002/jbm.a.33277
Publikováno v:
Journal of Veterinary Pharmacology and Therapeutics. 34:120-129
Au, A. Y., Hasenwinkel, J. M., Frondoza, C. G. Silybin inhibits interleukin-1β-induced production of pro-inflammatory mediators in canine hepatocyte cultures. J. vet. Pharmacol. Therap.34, 120–129. Hepatocytes are highly susceptible to cytokine st
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::eb167c26c0df2f2d9487a52d75c65490
https://doi.org/10.1111/j.1365-2885.2010.01200.x
https://doi.org/10.1111/j.1365-2885.2010.01200.x