Zobrazeno 1 - 10
of 47
pro vyhledávání: '"Carmelina Gemma"'
Publikováno v:
Neurobiology of Sleep and Circadian Rhythms, Vol 2, Iss , Pp 71-84 (2017)
Disorders of sleep and wakefulness occur in the majority of individuals who have experienced traumatic brain injury (TBI), with increased sleep need and excessive daytime sleepiness often reported. Behavioral and pharmacological therapies have limite
Externí odkaz:
https://doaj.org/article/0ce8b7a2d8c34e4884f623aa7f7d4128
Publikováno v:
Bio-Protocol, Vol 6, Iss 16 (2016)
Traumatic brain injury (TBI) affects millions of people worldwide; however, the immediate impact of TBI and the secondary injury mechanisms are still not fully understood. TBI can cause devastating neuromotor deficits in both acute and chronic stages
Externí odkaz:
https://doaj.org/article/fa379b7fb64c48e2b1055a6dde33cf2a
Autor:
Adam D Bachstetter, Jennifer Jernberg, Andrea Schlunk, Jennifer L Vila, Charles Hudson, Michael J Cole, R Douglas Shytle, Jun Tan, Paul R Sanberg, Cyndy D Sanberg, Cesario Borlongan, Yuji Kaneko, Naoki Tajiri, Carmelina Gemma, Paula C Bickford
Publikováno v:
PLoS ONE, Vol 5, Iss 5, p e10496 (2010)
Adult stem cells are present in many tissues including, skin, muscle, adipose, bone marrow, and in the brain. Neuroinflammation has been shown to be a potent negative regulator of stem cell and progenitor cell proliferation in the neurogenic regions
Externí odkaz:
https://doaj.org/article/9e7913c1b5744b24a65dbca442f2a60a
Autor:
Svitlana Garbuzova-Davis, Cyndy Davis Sanberg, Nicole Kuzmin-Nichols, Alison E Willing, Carmelina Gemma, Paula C Bickford, Christina Miller, Robert Rossi, Paul R Sanberg
Publikováno v:
PLoS ONE, Vol 3, Iss 6, p e2494 (2008)
Amyotrophic Lateral Sclerosis (ALS) is a multicausal disease characterized by motor neuron degeneration in the spinal cord and brain. Cell therapy may be a promising new treatment for this devastating disorder. We recently showed that a single low do
Externí odkaz:
https://doaj.org/article/b13ef9c08eee463aaf5d3cc20d9f7dba
Publikováno v:
BIO-PROTOCOL. 6
Autor:
Josh M. Morganti, Bethany Grimmig, Brent J. Small, Paula C. Bickford, Carmelina Gemma, Kevin Nash, Sonali Ranjit
Publikováno v:
The Journal of Neuroscience. 32:14592-14601
The chemokine CX3CL1/fractalkine is expressed by neurons as a transmembrane-anchored protein that can be cleaved to yield a soluble isoform. However, the roles for these two types of endogenous CX3CL1 in neurodegenerative pathophysiology remain elusi
Autor:
Matthew Fister, Michael J. Cole, Paula C. Bickford, Adam D. Bachstetter, Charles Hudson, Carmelina Gemma
Publikováno v:
European Journal of Neuroscience. 26:2795-2803
Adult hippocampal neurogenesis dramatically decreases with increasing age, and it has been proposed that this decline contributes to age-related memory deficits. Central inflammation contributes significantly to the decrease in neurogenesis associate
Publikováno v:
Experimental Neurology. 196:298-307
Neuroinflammation plays a critical role in loss of dopamine neurons during brain injury and in neurodegenerative diseases. Diets enriched in foods with antioxidant and anti-inflammatory actions may modulate this neuroinflammation. The model of 6-hydr
Publikováno v:
The Journal of Neuroscience. 22:5813-5816
Diets high in antioxidant properties are known to reverse some deficits in neuronal and cognitive function that occur in aging animals. Antioxidants are also known to reduce levels of proinflammatory factors in the CNS. We report here that 6 weeks of
Autor:
Douglas B. Holmes, Michael H. Mesches, Boris Sepesi, Carmelina Gemma, Paula C. Bickford, Kevin S. Choo
Publikováno v:
The Journal of Neuroscience. 22:6114-6120
Antioxidants and diets supplemented with foods high in oxygen radical absorbance capacity (ORAC) reverse age-related decreases in cerebellar beta-adrenergic receptor function. We examined whether this effect was related to the antioxidant capacity of