Zobrazeno 1 - 10
of 36
pro vyhledávání: '"Carmela Zincarelli"'
Autor:
Carmela Zincarelli, Rosario Peluso, N. Pappone, Matteo Nicola Dario Di Minno, Salvatore Iervolino, Alessandro Di Minno, Paolo Pizzicato, Pasquale Ambrosino, Roberta Lupoli
Publikováno v:
Expert Opinion on Drug Safety. 14:1905-1913
Introduction: Many literature data support the possibility of an increased cardiovascular (CV) risk in psoriatic arthritis (PsA) patients compared with the general population. This cannot be entirely explained by the presence of traditional vascular
Autor:
N. Pappone, Carmela Zincarelli, Salvatore Iervolino, Roberta Lupoli, Rosario Peluso, Matteo Nicola Dario Di Minno, Reuven Mader
Publikováno v:
Rheumatology International. 35:2041-2046
Diffuse idiopathic skeletal hyperostosis (DISH) is characterized by ossification of different entheses. Psoriatic arthritis (PsA) is a seronegative spondyloarthritis associated with psoriasis. Given the possible overlap of the two diseases, we assess
Autor:
Carmela Zincarelli, Daniela Liccardo, Walter J. Koch, Pasquale Perrone Filardi, Claudio de Lucia, Valentina Parisi, Klara Komici, Giuseppe Rengo, Gennaro Pagano, Dario Leosco, Nicola Ferrara, Stefania Paolillo, Flavia Fusco, Alessandro Cannavo, Grazia Daniela Femminella
Publikováno v:
International Journal of Cardiology. 171:384-389
Background Short-term changes of neurohormones can give important prognostic information in heart failure (HF) patients. In this study, we evaluate whether changes in plasma Norepinephrine (NE) and serum N-terminal pro-brain natriuretic peptide (NT-p
Autor:
Roberto Puglia, Carmela Zincarelli, Daniela Liccardo, Alessandro Cannavo, Walter J. Koch, Joseph E. Rabinowitz, Nicola Ferrara, Maria Carmen De Angelis, Elisa Di Pietro, Bruno Trimarco, Maria Vittoria Barone, Timothy M. Palmer, Gennaro Pagano, Giuseppe Rengo, Dario Leosco, Plinio Cirillo, Antonio Rapacciuolo
Publikováno v:
Circulation. 128:1612-1622
Background— The sphingosine-1-phosphate receptor 1 (S1PR1) and β 1 -adrenergic receptor (β1AR) are G-protein–coupled receptors expressed in the heart. These 2 receptors have opposing actions on adenylyl cyclase because of differential G-protein
Autor:
C. De Lucia, Alessandro Cannavo, Nicola Ferrara, Carmela Zincarelli, Anastasios Lymperopoulos, Daniela Liccardo, Paola Gargiulo, Giuseppe Rengo, Dario Leosco, Walter J. Koch, Gennaro Pagano, Grazia Daniela Femminella, P. Perrone Filardi
Publikováno v:
British Journal of Pharmacology. 166:2430-2440
BACKGROUND AND PURPOSE Sympathetic nervous system (SNS) hyperactivity is characteristic of chronic heart failure (HF) and significantly worsens prognosis. The success of β-adrenoceptor antagonist (β-blockers) therapy in HF is primarily attributed t
Autor:
Claudio de Lucia, Fabio Marsico, Anastasios Lymperopoulos, Dario Leosco, Carmela Zincarelli, Pasquale Perrone-Filardi, Daniela Liccardo, Gennaro Pagano, Grazia Daniela Femminella, Giuseppe Rengo
Publikováno v:
Circulation: Heart Failure. 5:385-391
G-protein–coupled receptors (GPCRs) are a superfamily of more than 1000 membrane proteins that respond to a wide spectrum of extracellular signals, modulating various physiopathological processes.1,2 Several GPCRs, such as adrenergic, angiotensin,
Autor:
Carmela Zincarelli, Erhe Gao, Tung O. Chan, Deana Mikhalkova, Jianliang Song, Yonghong Lei, Jin Zhang, Karsten Peppel, Arthur M. Feldman, Xue Li, Walter J. Koch, Valerie D. Myers, Joseph Y. Cheung
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 301:H1932-H1940
Akt2 protein kinase has been shown to promote cell migration and actin polymerization in several cell types, including macrophages. Because migrating macrophages constitute an important inflammatory response after myocardial ischemia, we determined c
Publikováno v:
Clinical and Translational Science. 3:81-89
Cardiac gene transfer is an attractive tool for developing novel heart disease treatments. Adeno-associated viral (AAV) vectors are widely used to mediate transgene expression in animal models and are being evaluated for human gene therapy. However,
Autor:
Giuseppe Furgi, Franco Rengo, Carmela Zincarelli, Gennaro Galasso, Grazia Daniela Femminella, Dino Franco Vitale, Dario Leosco, Luca Golino, Giuseppe Rengo, Federico Piscione
Publikováno v:
The Journals of Gerontology Series A: Biological Sciences and Medical Sciences. :758-763
Background. an active lifestyle is associated with a reduced cardiovascular risk in middle-aged as well as in elderly patients. In the present study, we investigated the association between physical activity habits of elderly participants prior to co
Autor:
Carmela Zincarelli, Luca Golino, Emma Sanzari, Vincenzo Cimini, Walter J. Koch, Dario Leosco, Federico Piscione, Michele Ciccarelli, Giovanna Giuseppina Altobelli, Giuseppe Rengo, Franco Rengo, Gabriella De Lisa, Bruno Trimarco, Francesca Fortunato, Gennaro Galasso, Guido Iaccarino
Publikováno v:
Scopus-Elsevier
Downregulation of hypoxia-inducible factor 1 (HIF-1) and vascular endothelial growth factor (VEGF) are shown to be involved in age-dependent impairment of angiogenesis. In this study, we explore whether prior exercise is able to affect these molecula