Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Carmela Palermo"'
Publikováno v:
PLoS ONE, Vol 3, Iss 1, p e1427 (2008)
The protein kinase Chk1 is an essential component of the DNA damage checkpoint pathway. Chk1 is phosphorylated and activated in the fission yeast Schizosaccharomyces pombe when cells are exposed to agents that damage DNA. Phosphorylation, kinase acti
Externí odkaz:
https://doaj.org/article/c738b9c06d4c4ab1a63e29c7daf8c8b0
Autor:
Karen E. Hunter, Jemila C. Kester, Carmela Palermo, Kenishana Simpson, Laura H. Tang, David S. Klimstra, Jin-Ping Li, Johanna A. Joyce, Israel Vlodavsky
Publikováno v:
Oncogene. 33:1799-1808
Heparan sulfate proteoglycans are an important and abundant component of the extracellular matrix, which undergo substantial remodeling throughout tumorigenesis via the enzymatic activity of heparanase. Heparanase has been shown to be upregulated in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0afd67c912d5191ba48fcf70a19d6850
https://doi.org/10.1038/onc.2013.142
https://doi.org/10.1038/onc.2013.142
Autor:
Carmela Palermo, Johanna A. Joyce
Publikováno v:
Trends in Pharmacological Sciences. 29:22-28
Proteolytic activity is required for several key pro-tumorigenic processes: angiogenesis, invasion and metastasis. Consequently, increases in protease expression and activity are frequently reported in human cancers, and correlate with malignant prog
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d6d02015b58232cc212147027bce365
https://doi.org/10.1016/j.tips.2007.10.011
https://doi.org/10.1016/j.tips.2007.10.011
Autor:
Carmela Palermo, Bedrick B. Gadea, Johanna A. Joyce, Israel Vlodavsky, Tamar Peretz, Ghada Abboud-Jarrous, Ruth Atzmon
Publikováno v:
The Journal of biological chemistry. 283(26)
Heparanase is an endo-β-d-glucuronidase that degrades heparan sulfate in the extracellular matrix and on the cell surface. Human proheparanase is produced as a latent protein of 543 amino acids whose activation involves excision of an internal linke
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b8accb08d75ac9debf889ee91f17f4ee
https://pubmed.ncbi.nlm.nih.gov/18450756
https://pubmed.ncbi.nlm.nih.gov/18450756
Publikováno v:
PLoS ONE, Vol 3, Iss 1, p e1427 (2008)
PLoS ONE
PLoS ONE
Background The protein kinase Chk1 is an essential component of the DNA damage checkpoint pathway. Chk1 is phosphorylated and activated in the fission yeast Schizosaccharomyces pombe when cells are exposed to agents that damage DNA. Phosphorylation,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::99f49a4469bce8bf589dbbd6ede22ad4
http://europepmc.org/articles/PMC2173936?pdf=render
http://europepmc.org/articles/PMC2173936?pdf=render
Autor:
Carmela, Palermo, Nancy C, Walworth
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 296
Eukaryotic cells regulate progression through the cell cycle in response to DNA damage. Cell cycle checkpoints are the signal transduction pathways that couple the detection of DNA damage to the proteins that control transitions in the cell cycle. Th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d8ba7bc0ab71b5e969a44b445e34857c
https://pubmed.ncbi.nlm.nih.gov/15576943
https://pubmed.ncbi.nlm.nih.gov/15576943
Autor:
Carmela Palermo, Nancy C. Walworth
Eukaryotic cells regulate progression through the cell cycle in response to DNA damage. Cell cycle checkpoints are the signal transduction pathways that couple the detection of DNA damage to the proteins that control transitions in the cell cycle. Th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dc5adf31104f4f6880521b698e92444f
https://doi.org/10.1385/1-59259-857-9:345
https://doi.org/10.1385/1-59259-857-9:345
Publikováno v:
Molecular and cellular biology. 24(9)
The conserved protein kinase Chk1 mediates cell cycle progression and consequently the ability of cells to survive when exposed to DNA damaging agents. Cells deficient in Chk1 are hypersensitive to such agents and enter mitosis in the presence of dam
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f72eb56bddc5b403c4ffbee352fae9c
https://pubmed.ncbi.nlm.nih.gov/15082762
https://pubmed.ncbi.nlm.nih.gov/15082762
Autor:
Holly, Capasso, Carmela, Palermo, Shanhong, Wan, Hui, Rao, P, John Ulrik, J, O'Connell Matthew, C, Walworth Nancy
Publikováno v:
Journal of Cell Science; December 2002, Vol. 115 Issue: 23 p4555-64, 10p
Publikováno v:
Macromolecular Biorecognition ISBN: 9781461289449
Large experimental evidence has recently well established that DNA in biological systems is supercoiled and that its behaviour is governed by topology (1,2).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cea5e5ac54bf570dadef5c9238e3b3ee
https://doi.org/10.1007/978-1-4612-4600-8_14
https://doi.org/10.1007/978-1-4612-4600-8_14