Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Carmela Fischetti"'
Autor:
Claudio Trapella, Anna Rizzi, Giuliano Marzola, Remo Guerrini, Jorgen S. Petersen, Carmela Fischetti, Elaine C. Gavioli, Girolamo Calo
Publikováno v:
Peptides. 30:248-255
ZP120 is a nociceptin/orphanin FQ (N/OFQ) peptide receptor (NOP) ligand. In previous studies, the effects of ZP120 were found to be sensitive to J-113397 in mouse tissues while resistant to UFP-101 in rat tissues. The aim of this study was to further
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e72d1b5e5ebaa2f5b44fdd2368a291db
https://doi.org/10.1016/j.peptides.2008.10.001
https://doi.org/10.1016/j.peptides.2008.10.001
Publikováno v:
British Journal of Pharmacology. 152:549-555
Background and purpose: Nocistatin (NST) is a neuropeptide generated from cleavage of the nociceptin/orphanin FQ (N/OFQ) precursor. Evidence has been presented that NST acts as a functional antagonist of N/OFQ, although NST receptor and transduction
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1036161e8e8462c6cfea1e2ac77d658a
https://doi.org/10.1038/sj.bjp.0707377
https://doi.org/10.1038/sj.bjp.0707377
Autor:
Richard D Wainford, Anna Rizzi, Girolamo Calo, Remo Guerrini, Severo Salvadori, Anna Baldisserotto, Giuliano Marzola, Carmela Fischetti, Daniel R. Kapusta, Domenico Regoli, Barbara Spagnolo
Publikováno v:
Peptides. 28:1240-1251
[(pF)Phe 4 Aib 7 Arg 14 Lys 15 ]N/OFQ-NH 2 (UFP-112) has been designed as a novel ligand for the nociceptin/orphanin FQ (N/OFQ) peptide receptor (NOP) by combining into the same peptide different chemical modifications reported to increase N/OFQ pote
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::45c1bdf4ac682a9b8f3b4bc53ffd3033
https://doi.org/10.1016/j.peptides.2007.04.020
https://doi.org/10.1016/j.peptides.2007.04.020
Autor:
Sándor Benyhe, Carmela Fischetti, Fruzsina Babos, Anna Borsodi, Sándor Bajusz, Valeria Camarda, Girolamo Calo, Engin Bojnik, Anna Magyar
Publikováno v:
Brain research bulletin. 81(4-5)
Nociceptin/orphanin FQ (N/OFQ) is an endogenous neuropeptide, which is widely distributed in central and peripheral nervous system. Some N/OFQ sequence unrelated hexapeptides can effectively bind to the N/OFQ peptide (NOP) receptor and they were used
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::475802e545ba608f1bcc28ee00bbccc9
https://pubmed.ncbi.nlm.nih.gov/19800951
https://pubmed.ncbi.nlm.nih.gov/19800951
Autor:
Michela Pela, Valeria Camarda, John McDonald, Carmela Fischetti, Remo Guerrini, David G. Lambert, Domenico Regoli, Anna Rizzi, Claudio Trapella, Girolamo Calo, Severo Salvadori
Compound 24, 1-benzyl-N-[3-[spiroisobenzofuran-1(3H),4'-piperidin-1-yl]propyl] pyrrolidine-2-carboxamide was recently identified as a nociceptin/orphanin FQ (N/OFQ) peptide receptor (NOP) ligand. In this study, the in vitro and in vivo pharmacologica
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::361051deff0638121abb670bcead1e16
http://hdl.handle.net/11577/3387406
http://hdl.handle.net/11577/3387406
Autor:
Claudio Trapella, Ilaria Lazzari, Remo Guerrini, Girolamo Calo, Valeria Camarda, Michela Pela, John McDonald, David G. Lambert, Severo Salvadori, Carmela Fischetti, Anna Rizzi, Domenico Regoli
Twelve derivatives of the nociceptin/orphanin FQ (N/OFQ) receptor (NOP) antagonist 1-benzyl-N-{3-[spiroisobenzofuran-1(3H),4′-piperidin-1-yl]propyl} pyrrolidine-2-carboxamide (Comp 24) were synthesized and tested in binding experiments performed on
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d6a38ab43c41af4907fcdf27aad1751f
http://hdl.handle.net/11577/3387350
http://hdl.handle.net/11577/3387350
Autor:
Remo Guerrini, Girolamo Calo, Salvadori Severo, Valeria Camarda, Paola Molinari, Carmela Fischetti, Evi Kostenis, Nicholas Anzellotti, Caterina Ambrosio, Domenico Regoli, Claudio Trapella
In this study, the Gαqi5 protein was used to force the human nociceptin/orphanin FQ (N/OFQ) peptide (NOP) receptor to signal through the Ca2+ pathway in CHO cells. [Ca2+]i levels were monitored using the fluorometer FlexStation II and the Ca2+ dye F
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::873945f0e20fb5abaac1b033f8d74529
http://hdl.handle.net/11577/3386376
http://hdl.handle.net/11577/3386376
Autor:
Carmela Fischetti, Martina Fantin, T. A. Barnes, Chris Hebbes, Claudio Trapella, Domenico Regoli, Anna Rizzi, Giulia Fanton, Giacomo Carrà, Michele Morari, John McDonald, Barbara Spagnolo, Dave G. Lambert, Girolamo Calo
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 321(3)
The compound SB-612111 [(-)-cis-1-methyl-7-[[4-(2,6-dichlorophenyl)piperidin-1-yl]methyl]-6,7,8,9-tetrahydro-5H-benzocyclohepten-5-ol] was recently identified as a selective antagonist for the nociceptin/orphanin FQ (N/OFQ) peptide receptor (NOP). In
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::848260abb76f7874ccb86e368e189780
https://pubmed.ncbi.nlm.nih.gov/17329552
https://pubmed.ncbi.nlm.nih.gov/17329552
Autor:
John McDonald, Marika Arduin, David G. Lambert, Girolamo Calo, Remo Guerrini, Severo Salvadori, Erika Marzola, Carmela Fischetti, Barbara Spagnolo, Giacomo Carrà, Domenico Regoli, Claudio Trapella
Publikováno v:
Bioorganicmedicinal chemistry. 15(13)
Previous structure-activity and NMR studies on nociceptin/orphanin FQ (N/OFQ) demonstrated that Aib substitution of Ala(7) and/or Ala(11) increases the peptide potency through an alpha helix structure induction mechanism. On these bases we synthesise
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1fee9573570b463cfebf6b0e49c6b2e6
https://pubmed.ncbi.nlm.nih.gov/17490886
https://pubmed.ncbi.nlm.nih.gov/17490886
Autor:
André Andrade, Anna Carmela Fischetti
Publikováno v:
7th International Congress of the Brazilian Geophysical Society.
As imagens da parede do poco sao amplamente utilizadas por geologos e engenheiros de petroleo para identificar eventos geologicos nas paredes de pocos abertos e na inspecao dos tubos de revestimento. As ferramentas de imageamento acustico produzem im
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7171d5ba84ab3e14f15b0d90b80d0b3e
https://doi.org/10.3997/2214-4609-pdb.217.386
https://doi.org/10.3997/2214-4609-pdb.217.386