Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Carmela Calés"'
Autor:
Jorge Melones-Herrero, Sonia Alcalá, Laura Ruiz-Cañas, Carlos Benítez-Buelga, Sandra Batres-Ramos, Carmela Calés, Oscar Lorenzo, Rosario Perona, Adoración G. Quiroga, Bruno Sainz, Isabel Sánchez-Pérez
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-16 (2024)
Abstract Cisplatin-based chemotherapy has associated clinical disadvantages, such as high toxicity and resistance. Thus, the development of new antitumor metallodrugs able to overcome different clinical barriers is a public healthcare priority. Here,
Externí odkaz:
https://doaj.org/article/3950323370b4436097434ef697f118ef
Autor:
Jorge Melones-Herrero, Patricia Delgado-Aliseda, Sofía Figueiras, Javier Velázquez-Gutiérrez, Adoración Gomez Quiroga, Carmela Calés, Isabel Sánchez-Pérez
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 14, p 7739 (2024)
Gastric cancer prognosis is still notably poor despite efforts made to improve diagnosis and treatment of the disease. Chemotherapy based on platinum agents is generally used, regardless of the fact that drug toxicity leads to limited clinical effica
Externí odkaz:
https://doaj.org/article/f65a9da9cee24cde85cb845cf7b2710f
Autor:
Paula Escudero, Ramón Merino, Jesús Osada, Ángela Sánchez, Cristina Barranquero, Susana Alemany, Ana Aranda, Marta Muñoz, Carlos Sanz-Garcia, Carmela Calés, Maria-Jesús Sanz, Constanza Contreras-Jurado
Publikováno v:
ResearcherID
Digital.CSIC. Repositorio Institucional del CSIC
instname
Digital.CSIC. Repositorio Institucional del CSIC
instname
[Objective]: Map3k8 (Cot/Tpl2) activates the MKK1/2-ERK1/2, MAPK pathway downstream from interleukin-1R, tumor necrosis factor-αR, NOD-2R (nucleotide-binding oligomerization domain-like 2R), adiponectinR, and Toll-like receptors. Map3k8 plays a key
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
instname
instname
GATA1 is a hematopoietic transcription factor essential for expression of most genes encoding erythro-megakaryocytic proteins, i.e., globins and platelet glycoproteins. A role for GATA1 as a cell proliferation regulator has been proposed, as some of
Autor:
Carmela Calés, Haruhiko Koseki, Miguel Vidal, Tomokatsu Ikawa, Mónica Bravo, Katarzyna Starowicz, Leticia Pavón, Claudia Pérez
Publikováno v:
Repositorio Institucional de la Consejería de Sanidad de la Comunidad de Madrid
Consejería de Sanidad de la Comunidad de Madrid
Consejería de Sanidad de la Comunidad de Madrid
Polycomb chromatin modifiers regulate hematopoietic pluripotent stem and progenitor cell self-renewal and expansion. Polycomb complex redundancy and biochemical heterogeneity complicate the unraveling of the functional contributions of distinct compo
Autor:
Carmela Calés, Mónica Bravo, Katarzyna Starowicz, Sonia Barroso, Miguel Vidal, Fabio Nicolini, Andrés Aguilera
Publikováno v:
Biblos-e Archivo. Repositorio Institucional de la UAM
instname
idUS. Depósito de Investigación de la Universidad de Sevilla
instname
idUS. Depósito de Investigación de la Universidad de Sevilla
The functions of polycomb products extend beyond their well-known activity as transcriptional regulators to include genome duplication processes. Polycomb activities during DNA replication and DNA damage repair are unclear, particularly without induc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::082c85e433856b01ec743f6a480fcb75
http://hdl.handle.net/10486/672261
http://hdl.handle.net/10486/672261
Autor:
Lucia Jimenez, Yenny Montenegro, Sandra Serrano Del Hoyo, Carmela Calés, Miguel Vidal, Claudia Pérez, Katarzyna Starowicz
Publikováno v:
Experimental Hematology. 53:S66
Publikováno v:
British Journal of Haematology. 114:458-465
Cord blood (CB) has successfully been used as a stem cell source for haemopoietic reconstitution. However, a significant delay in platelet engraftment is consistently found in CB versus adult peripheral blood (PB) or bone marrow transplants. We sough
Publikováno v:
Oncogene. 19:1820-1833
Megakaryocytes become polyploid by entering a truncated cell cycle, consisting of alternate S phases and abortive mitoses. We have investigated the regulation of the G1/S transition by comparing two megakaryoblastic cell lines, HEL and K562, which re
Autor:
Teresa Melgar, Leticia Pavón, Claudia Pérez, Haruhiko Koseki, Miguel Vidal, Carmela Calés, Iván Serrano, Monica Roman-Trufero, Mitsuhiro Endoh
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
instname
instname
11 pages, 7 figures.-- et al.
Polycomb group (PcG) proteins act as positive regulators of cell proliferation. Ring1B is a PcG gene essential for embryonic development, but its contribution to cell turnover in regenerating tissues in not known. H
Polycomb group (PcG) proteins act as positive regulators of cell proliferation. Ring1B is a PcG gene essential for embryonic development, but its contribution to cell turnover in regenerating tissues in not known. H
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0111b1cbde94822e2d28a48223bdfd65
http://hdl.handle.net/10261/25055
http://hdl.handle.net/10261/25055