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of 9
pro vyhledávání: '"Carmela A. Skillman"'
2-Deoxyglucose Tissue Levels and Insulin Levels Following Tolazamide Dosing in Normal and Obese Mice
Autor:
H. P. Fletcher, Carmela A. Skillman
Publikováno v:
Experimental and Clinical Endocrinology & Diabetes. 87:288-298
The effect of tolazamide (TZ), a sulfonylurea, on 14C-2-deoxyglucose (14C-2DG) tissue distribution and insulin levels of normal and obese mice was investigated using an in vivo physiological method. Acute doses of TZ (50 mg/kg ip) increased 14C-2DG l
Autor:
Carmela A. Skillman, Philip Raskin
Publikováno v:
Diabetes care. 20(4)
OBJECTIVE To determine the effect over a 4-week period of varying doses of BTS 67,582, a novel nonsulfonylurea insulinotropic agent, on fasting plasma glucose (FPG) levels in sulfonylurea-responsive NIDDM patients. RESEARCH DESIGN AND METHODS This wa
Autor:
Tariq A. Siddiqi, Menachem Miodovnik, John B. Butler, Francis B. Mimouni, Reginald C. Tsang, Carmela A. Skillman, Jane Holroyde
Publikováno v:
American Journal of Perinatology. 4:106-114
Infants of insulin-dependent diabetic mothers are at risk for neonatal polycythemia, hyperbilirubinemia, respiratory distress syndrome (RDS), and hypoglycemia. The purpose of this study was to determine whether labor and delivery management of diabet
Publikováno v:
Anesthesia & Analgesia. 68:101-104
We evaluated the clinical effectiveness of esmolol, an ultra-short-acting, cardioselective beta-adrenergic receptor blocker, in controlling sinus tachycardia and increased systolic blood pressure occurring perioperatively in 30 ASA physical status II
Autor:
Tariq A. Siddiqi, James S. Wendel, John B. Butler, Jane C. Holroyde, Menachem Miodovnik, Carmela A. Skillman
Publikováno v:
American Journal of Obstetrics and Gynecology. 153:439-442
Insulin-dependent diabetic women without adequate glucose control have a higher rate of spontaneous abortions than does the general population of pregnant women. The present study examined whether insulin-dependent diabetic women who experienced spon
Autor:
Vicki S. Hertzberg, Kenneth E. Clark, Carmela A. Skillman, Deborah J. Harrington, Menachem Miodovnik
Publikováno v:
American Journal of Obstetrics and Gynecology. 154:394-401
The fetus of the pregnant diabetic woman is exposed to hyperglycemia frequently accompanied by ketoacidosis. Previous studies have demonstrated that beta-hydroxybutyrate, a major ketone body, crosses the ovine placenta in significant amounts, leading
Autor:
Catherine E. Mack, Carmela A. Skillman, Kenneth E. Clark, Diane E. Brockman, Kathryn A. Cashner
Publikováno v:
American Journal of Obstetrics and Gynecology. 155:1305-1310
Antipyrine and 4-aminoantipyrine have been used for approximately 20 years to measure uterine and umbilical blood flow. Fetal infusion of 4-aminoantipyrine has been shown to decrease myometrial activity and to significantly lower prostaglandin F2 alp
Publikováno v:
American journal of perinatology. 5(4)
Studies with pregnant sheep are reviewed, which were designed to investigate whether short-term episodes of maternal hyperglycemia or hyperketonemia were detrimental to the fetus, whether ketones can cross the ovine placenta, and whether the combinat
Autor:
Carmela A. Skillman, Kenneth E. Clark
Publikováno v:
Biology of the neonate. 51(4)
Fetal beta-endorphin release has been associated with fetal hypoxia. The purpose of this study was to assess the degree of uterine blood flow reduction needed to elicit fetal beta-endorphin release in the sheep since there is a large reserve of oxyge