Zobrazeno 1 - 10 of 74 pro vyhledávání: '"Carmel Murone"'
2
Akademický článek
DUSP5 is methylated in CIMP-high colorectal cancer but is not a major regulator of intestinal cell proliferation and tumorigenesis
Autor: Lars Tögel, Rebecca Nightingale, Rui Wu, Anderly C. Chüeh, Sheren Al-Obaidi, Ian Luk, Mercedes Dávalos-Salas, Fiona Chionh, Carmel Murone, Daniel D. Buchanan, Zac Chatterton, Oliver M. Sieber, Diego Arango, Niall C. Tebbutt, David Williams, Amardeep S. Dhillon, John M. Mariadason
Publikováno v: Scientific Reports, Vol 8, Iss 1, Pp 1-11 (2018)
Abstract The ERK signalling pathway regulates key cell fate decisions in the intestinal epithelium and is frequently dysregulated in colorectal cancers (CRCs). Variations in the dynamics of ERK activation can induce different biological outcomes and
Externí odkaz: https://doaj.org/article/a151607c9cc44b65a4170afe0f9837f7
Zobrazit plný text záznamu
3
Akademický článek
Development of monoclonal anti-PDGF-CC antibodies as tools for investigating human tissue expression and for blocking PDGF-CC induced PDGFRα signalling in vivo.
Autor: Hong Li, Manuel Zeitelhofer, Ingrid Nilsson, Xicong Liu, Laura Allan, Benjamin Gloria, Angelo Perani, Carmel Murone, Bruno Catimel, A Munro Neville, Fiona E Scott, Andrew M Scott, Ulf Eriksson
Publikováno v: PLoS ONE, Vol 13, Iss 7, p e0201089 (2018)
PDGF-CC is a member of the platelet-derived growth factor (PDGF) family that stimulates PDGFRα phosphorylation and thereby activates intracellular signalling events essential for development but also in cancer, fibrosis and neuropathologies involvin
Externí odkaz: https://doaj.org/article/3f68df07fed041008b6799d6093342ab
Zobrazit plný text záznamu
4
Akademický článek
In vivo imaging of cellular proliferation in renal cell carcinoma using 18F-fluorothymidine PET
Autor: Peter K. Wong, Sze Ting Lee, Carmel Murone, John Eng, Nathan Lawrentschuk, Salvatore U. Berlangieri, Kunthi Pathmaraj, Graeme J. O'Keefe, John Sachinidis, Amanda J. Byrne, Damien M. Bolton, Ian D. Davis, Andrew M. Scott
Publikováno v: Asia Oceania Journal of Nuclear Medicine and Biology, Vol 2, Iss 1, Pp 3-11 (2014)
Objective(s): The ability to measure cellular proliferation non-invasively in renal cell carcinoma may allow prediction of tumour aggressiveness and response to therapy. The aim of this study was to evaluate the uptake of 18Ffluorothymidine (FLT) PET
Externí odkaz: https://doaj.org/article/cab8e5155b144120aba430b682f6bc81
Zobrazit plný text záznamu
5
Akademický článek
PD-L1 and Tumor Infiltrating Lymphocytes as Prognostic Markers in Resected NSCLC.
Autor: Malaka Ameratunga, Khashayar Asadi, Xihui Lin, Marzena Walkiewicz, Carmel Murone, Simon Knight, Paul Mitchell, Paul Boutros, Thomas John
Publikováno v: PLoS ONE, Vol 11, Iss 4, p e0153954 (2016)
INTRODUCTION:Immune checkpoint inhibition has shifted treatment paradigms in non-small cell lung cancer (NSCLC). Conflicting results have been reported regarding the immune infiltrate and programmed death-ligand 1 (PD-L1) as a prognostic marker. We c
Externí odkaz: https://doaj.org/article/8ded8d565695400a8df2226657f469f4
Zobrazit plný text záznamu
6
Akademický článek
Hypoxia-controlled EphA3 marks a human endometrium-derived multipotent mesenchymal stromal cell that supports vascular growth.
Autor: Catherine To, Rae H Farnsworth, Mary E Vail, Chanly Chheang, Caroline E Gargett, Carmel Murone, Carmen Llerena, Andrew T Major, Andrew M Scott, Peter W Janes, Martin Lackmann
Publikováno v: PLoS ONE, Vol 9, Iss 11, p e112106 (2014)
Eph and ephrin proteins are essential cell guidance cues that orchestrate cell navigation and control cell-cell interactions during developmental tissue patterning, organogenesis and vasculogenesis. They have been extensively studied in animal models
Externí odkaz: https://doaj.org/article/1410d261dabe41f9a7e5929cbdda68bd
Zobrazit plný text záznamu
8
Expression of EGFR and conformational forms of EGFR in malignant pleural mesothelioma and its impact on survival
Autor: Sagun Parakh, Thomas John, Marzena Walkiewicz, Khashayer Asadi, Andrew M. Scott, Puey Ling Chia, Val Gebski, Carmel Murone, Prudence A. Russell, Fiona Scott, Bibhusal Thapa, Hui K Gan, Zhanqi Liu
Publikováno v: Lung Cancer. 153:35-41
Aim Conformational forms of the epidermal growth factor receptor (EGFR) are pro‐tumorigenic. The prevalence and impact of conformational forms of EGFR in malignant mesothelioma (MM) is unknown. We investigated expression of EGFR and conformational
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b622a844a17d9452596ad70efc1d57d1
https://doi.org/10.1016/j.lungcan.2020.12.028
Zobrazit plný text záznamu
9
Paracrine IL-6 Signaling Confers Proliferation between Heterogeneous Inflammatory Breast Cancer Sub-Clones
Autor: Riley J. Morrow, Amr H. Allam, Belinda Yeo, Siddhartha Deb, Carmel Murone, Elgene Lim, Cameron N. Johnstone, Matthias Ernst
Publikováno v: Cancers; Volume 14; Issue 9; Pages: 2292
Inflammatory breast cancer (IBC) describes a highly aggressive form of breast cancer of diverse molecular subtypes and clonal heterogeneity across individual tumors. Accordingly, IBC is recognized by its clinical signs of inflammation, associated wit
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1fed51cd8b30234bbd90e816df7b32a9
Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání

Omezení vyhledávání
Plný text Recenzováno Digitální knihovna AV ČR
Zdroje