Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Carly Roleder"'
Autor:
Elana Thieme, Nur Bruss, Duanchen Sun, Edward C. Dominguez, Daniel Coleman, Tingting Liu, Carly Roleder, Melissa Martinez, Krystine Garcia-Mansfield, Brian Ball, Patrick Pirrotte, Lili Wang, Zheng Xia, Alexey V. Danilov
Publikováno v:
Molecular Cancer, Vol 22, Iss 1, Pp 1-17 (2023)
Abstract Diffuse large B-cell lymphoma (DLBCL) exhibits significant genetic heterogeneity which contributes to drug resistance, necessitating development of novel therapeutic approaches. Pharmacological inhibitors of cyclin-dependent kinases (CDK) de
Externí odkaz:
https://doaj.org/article/2ef2e1767bf742bb916cefc948518a5f
Autor:
Elana Thieme, Tingting Liu, Nur Bruss, Carly Roleder, Vi Lam, Xiaoguang Wang, Tamilla Nechiporuk, Geoffrey Shouse, Olga V. Danilova, Daniel Bottomly, Shannon K. McWeeney, Jeffrey W. Tyner, Stephen E. Kurtz, Alexey V. Danilov
Publikováno v:
Cell Death and Disease, Vol 13, Iss 3, Pp 1-11 (2022)
Abstract Aberrant B-cell receptor (BCR) signaling is a key driver in lymphoid malignancies. Bruton tyrosine kinase (BTK) inhibitors that disrupt BCR signaling have received regulatory approvals in therapy of mantle cell lymphoma (MCL). However, respo
Externí odkaz:
https://doaj.org/article/6ba6538ef93547b086ba5fe9d9f53329
Autor:
Xiaoguang Wang, Canping Chen, Dan Vuong, Sonia Rodriguez-Rodriguez, Vi Lam, Carly Roleder, Jing H. Wang, Swetha Kambhampati, Allison Berger, Nathan Pennock, Pallawi Torka, Francisco Hernandez-Ilizaliturri, Tanya Siddiqi, Lili Wang, Zheng Xia, Alexey V. Danilov
Publikováno v:
Leukemia.
Neddylation is a sequential enzyme-based process which regulates the function of E3 Cullin-RING ligase (CRL) and thus degradation of substrate proteins. Here we show that CD8+ T cells are a direct target for therapeutically relevant anti-lymphoma act