Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Carly M. Bliss"'
Autor:
Carly M. Bliss, Sarah L. Hulin-Curtis, Marta Williams, Mahulena Marušková, James A. Davies, Evelina Statkute, Alexander T. Baker, Louise Stack, Lucas Kerstetter, Lauren E. Kerr-Jones, Kate F. Milward, Gabrielle Russell, Sarah J. George, Luned M. Badder, Richard J. Stanton, Lynda Coughlan, Ian R. Humphreys, Alan L. Parker
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 32, Iss 3, Pp 101308- (2024)
Adenoviruses (Ads) have demonstrated significant success as replication-deficient (RD) viral vectored vaccines, as well as broad potential across gene therapy and cancer therapy. Ad vectors transduce human cells via direct interactions between the vi
Externí odkaz:
https://doaj.org/article/2537722157ec439c93f92451f7495d20
Autor:
Carly M. Bliss, Raffael Nachbagauer, Chiara Mariottini, Frans Cuevas, Jodi Feser, Abdi Naficy, David I. Bernstein, Jeffrey Guptill, Emmanuel B. Walter, Francesco Berlanda-Scorza, Bruce L. Innis, Adolfo García-Sastre, Peter Palese, Florian Krammer, Lynda Coughlan
Publikováno v:
EBioMedicine, Vol 104, Iss , Pp 105153- (2024)
Summary: Background: The development of a universal influenza virus vaccine, to protect against both seasonal and pandemic influenza A viruses, is a long-standing public health goal. The conserved stalk domain of haemagglutinin (HA) is a promising va
Externí odkaz:
https://doaj.org/article/c9ca6df22ec740d499055ef8fed469f9
Publikováno v:
Viruses, Vol 16, Iss 6, p 973 (2024)
Pathogenic adenovirus (Ad) infections are widespread but typically mild and transient, except in the immunocompromised. As vectors for gene therapy, vaccine, and oncology applications, Ad-based platforms offer advantages, including ease of genetic ma
Externí odkaz:
https://doaj.org/article/d6107fe71c3b4d5290b0da3fe14292ee
Autor:
Carly M. Bliss, Andrea J. Parsons, Raffael Nachbagauer, Jennifer R. Hamilton, Federica Cappuccini, Marta Ulaszewska, Jason P. Webber, Aled Clayton, Adrian V.S. Hill, Lynda Coughlan
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 16, Iss , Pp 108-125 (2020)
Adenoviral (Ad) vectors represent promising vaccine platforms for infectious disease. To overcome pre-existing immunity to commonly used human adenovirus serotype 5 (Ad5), vectors based on rare species or non-human Ads are being developed. However, t
Externí odkaz:
https://doaj.org/article/cd6a0c58b0e84b3aad7a70894ddac5d1
Publikováno v:
Frontiers in Immunology, Vol 11 (2021)
It is evident that the emergence of infectious diseases, which have the potential for spillover from animal reservoirs, pose an ongoing threat to global health. Zoonotic transmission events have increased in frequency in recent decades due to changes
Externí odkaz:
https://doaj.org/article/663d0a683c6c439e98e759acbb3a3f7b
Autor:
Victorine A. Mensah, Sophie Roetynck, Ebrima K. Kanteh, Georgina Bowyer, Amy Ndaw, Francis Oko, Carly M. Bliss, Ya Jankey Jagne, Riccardo Cortese, Alfredo Nicosia, Rachel Roberts, Flavia D’Alessio, Odile Leroy, Babacar Faye, Beate Kampmann, Badara Cisse, Kalifa Bojang, Stephen Gerry, Nicola K. Viebig, Alison M. Lawrie, Ed Clarke, Egeruan B. Imoukhuede, Katie J. Ewer, Adrian V. S. Hill, Muhammed O. Afolabi
Publikováno v:
Frontiers in Immunology, Vol 8 (2017)
BackgroundHeterologous prime-boost vaccination with chimpanzee adenovirus 63 (ChAd63) and modified vaccinia virus Ankara (MVA) encoding multiple epitope string thrombospondin-related adhesion protein (ME-TRAP) has shown acceptable safety and promisin
Externí odkaz:
https://doaj.org/article/ec79be823a6948b69302a94bf68cd4c9
Autor:
Carly M. Bliss, Alec W. Freyn, Tom G. Caniels, Victor H. Leyva-Grado, Raffael Nachbagauer, Weina Sun, Gene S. Tan, Virginia L. Gillespie, Meagan McMahon, Florian Krammer, Adrian V.S. Hill, Peter Palese, Lynda Coughlan
Publikováno v:
Molecular therapy, 30(5), 2024-2047. Nature Publishing Group
Conventional influenza vaccines fail to confer broad protection against diverse influenza A viruses with pandemic potential. Efforts to develop a universal influenza virus vaccine include refocusing immunity towards the highly conserved stalk domain
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::27ae760cfa9ec74e4507ccc9391dd171
https://orca.cardiff.ac.uk/id/eprint/146715/3/1-s2.0-S1525001622000119-main.pdf
https://orca.cardiff.ac.uk/id/eprint/146715/3/1-s2.0-S1525001622000119-main.pdf
Autor:
Maha Othman, Alexander T. Baker, Elena Gupalo, Abdelrahman Elsebaie, Carly M. Bliss, Matthew T. Rondina, David Lillicrap, Alan L. Parker
Publikováno v:
Journal of Thrombosis and Haemostasis. 21:1066
Autor:
Matthew T. Rondina, Elena Gupalo, Carly M. Bliss, David Lillicrap, Abdelrahman Elsebaie, Alexander T. Baker, Maha Othman, Alan L. Parker
Publikováno v:
Journal of Thrombosis and Haemostasis
Vaccine-induced immune thrombotic thrombocytopenia (VITT), or thrombotic thrombocytopenic syndrome (TTS), has caused global concern. VITT is characterized by thrombosis and thrombocytopenia following COVID-19 vaccinations with the AstraZeneca ChAdOx1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::812650950f512fd47538138adef4b9fc
https://doi.org/10.31219/osf.io/d8ut5
https://doi.org/10.31219/osf.io/d8ut5
Autor:
Amit Kapoor, Dung Nguyen, Senthil Chinnakannan, Hannah Sharpe, Isabelle Dietrich, Michael A. Jarvis, Claire Hutchings, Carly M. Bliss, Kathrin Heim, Eleanor Barnes, Wenqin Li, Peter Simmonds, Paul Klenerman, Erwan Atcheson
Publikováno v:
Hepatology (Baltimore, Md.)
Background and Aims:The lack of immunocompetent small animal models for hepatitis C virus (HCV) has greatly hindered the development of effective vaccines. Using rodent hepacivirus (RHV), a homolog of HCV that shares many characteristics of HCV infec