Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Carly E. Rolph"'
Autor:
Namita D. Neerukonda, Megan M. Lafferty, Carly E. Rolph, Fernando Banales Mejia, Courtney L. Franceschi, Erin T. Pelkey, Deborah O. Kwansare, Patricia Mowery, Nathanyal J. Truax, Maeve H. Kean
Publikováno v:
Bioorganicmedicinal chemistry letters. 27(2)
Analogs containing a central 3-pyrrolin-2-one core with different methoxyphenyl and/or indole substituents were prepared and tested for anti-proliferative activity in U-937 cells. The most efficacious analogs were non-rigid, (non-fused) contained met
Autor:
Catherine R. Downey, Maeve K. Holton, Guanqun Li, Erin T. Pelkey, Stephen R. Bruening, Taryn M. White, Katherine M. Delaney, Amy A. van Loon, Carly E. Rolph, Sarah J. Pelkey
Publikováno v:
ChemInform. 46
The cyclization precursors are prepared following the sequence shown for (V) or a modification thereof.
Autor:
Erin T. Pelkey, Stephen R. Bruening, Maeve K. Holton, Sarah J. Pelkey, Katherine M. Delaney, Carly E. Rolph, Guanqun Li, Amy A. van Loon, Catherine R. Downey, Taryn M. White
Publikováno v:
The Journal of Organic Chemistry
A flexible synthesis of dibenzo[e,g]isoindol-1-ones has been developed. Dibenzo[e,g]isoindol-1-ones represent simplified benzenoid analogues of biological indolo[2,3-a]pyrrolo[3,4-c]carbazol-5-ones (indolocarbazoles), compounds that have demonstrated