Zobrazeno 1 - 10
of 54
pro vyhledávání: '"Carlton R. Cooper"'
Autor:
Peace C. Asuzu, Nicholas S. Trompeter, Carlton R. Cooper, Samuel A. Besong, Alberta N. A. Aryee
Publikováno v:
Molecules, Vol 27, Iss 3, p 1087 (2022)
Plant-derived natural products are significant resources for drug discovery and development including appreciable potentials in preventing and managing oxidative stress, making them promising candidates in cancer and other disease therapeutics. Their
Externí odkaz:
https://doaj.org/article/ff121cc11e48495ab57fa4eeee4c971d
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 4, Iss 3, Pp 191-194 (2002)
Integrin αvβ3 is involved in varied cell biological activities, including angiogenesis, cell adhesion, and migration on several extracellular matrix components. Although αvβ3 is not typically expressed in epithelial cells, it is expressed in macr
Externí odkaz:
https://doaj.org/article/dd78d19342e1455089e4b28b778002cd
This review article seeks to provide relevant information about the applicability of cell-based assays in assessing cytotoxicity of phytochemicals in light of several traditional methods available. Phenolic compounds and other phytochemicals are sign
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d8a62903da103a9173b1428934a8678
Autor:
Robert A. Sikes, James M Kuczmarski, William B. Farquhar, Carlton R. Cooper, Jennifer J. DuPont, David G. Edwards, Mark D Darocki
Publikováno v:
Experimental Biology and Medicine. 236:1085-1092
A reduction in progenitor cell populations that help preserve vascular continuity and induce vascularization may accentuate endothelial cell apoptosis and dysfunction, ultimately contributing to organ failure and increased cardiovascular disease in c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::210acdb5096e8b47903f382114beec8c
https://doi.org/10.1258/ebm.2011.011008
https://doi.org/10.1258/ebm.2011.011008
Publikováno v:
The Biochemist. 32:36-39
Thalidomide (Figure 1) was derived from alpha-phnthaloylisoglutamine, a derivative of glutamic acid1 by Chemie Grünenthal GmbH, a West German Company in 1954. Thalidomide has a low level of toxicity and no LD50 could be established. Indeed, high dos
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a7c30407bec5644a29e1144e0e8e07f3
https://doi.org/10.1042/bio03205036
https://doi.org/10.1042/bio03205036
Autor:
Praveen K. Sharma, William E. Grizzle, Rajesh Singh, James W. Lillard, Carlton R. Cooper, Udai P. Singh, Leland W.K. Chung, Shesh N. Rai, Shailesh Singh, Kristian R. Novakovic
Publikováno v:
Cancer Letters. 283:29-35
Chemokines and corresponding receptor interactions have been shown to be involved in prostate cancer (PCa) progression and organ-specific metastasis. We have recently shown that PCa cell lines and primary prostate tumors express CXCR5, which correlat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d7040af30efeb881ebc5af476bc50ac
https://doi.org/10.1016/j.canlet.2009.03.022
https://doi.org/10.1016/j.canlet.2009.03.022
Autor:
Andrea M. Mastro, Michael N. VanSaun, Douglas R. Hurst, Carlton R. Cooper, Michelle D. Martin, Kedar S. Vaidya, Danny R. Welch, Conor C. Lynch
Publikováno v:
Cancer Research. 68:9578-9582
By analogy, the study of metastasis is like a group of blind people studying an elephant. Each describes the pachyderm based on the part (s)he touches, but none comprehends the whole elephant because his/her exposure is limited. Likewise, the complex
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7bfe84d17f6f5220aa67a133136b9bc3
https://doi.org/10.1158/0008-5472.can-08-3360
https://doi.org/10.1158/0008-5472.can-08-3360
Publikováno v:
Contemporary Clinical Trials. 29:878-886
We present statistical details for estimating an in vitro 50% inhibitory concentration (IC 50 ), based on several models for continuous response data fit to bone-marrow endothelial cell lines replicated in vehicle and at several dose increments. Nonl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a95ff5b71d4af1af543b672f530aebd
https://doi.org/10.1016/j.cct.2008.05.009
https://doi.org/10.1016/j.cct.2008.05.009
Autor:
James D. Gendernalik, Kirk J. Czymmek, Linda Sequeria, Mary C. Farach-Carson, Carlton D. Donald, Jill E. Lynch, Bianca Graves, Babette B. Weksler, Andrew Koemeter Cox, Kenneth L. van Golen, Jill A. Macoska, Robert A. Sikes, Angelo Evans, Freddie Pruitt, Katia Sol-Church, Carlton R. Cooper, Kenneth J. Pienta, Hassan Chaib, Rebecca S. Bullard
Publikováno v:
Journal of Cellular Biochemistry. 104:2298-2309
An unbiased cDNA expression phage library derived from bone-marrow endothelial cells was used to identify novel surface adhesion molecules that might participate in metastasis. Herein we report that reticulocalbin 1 (RCN1) is a cell surface-associate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b5c9bda56e7babd9d6902898baa4805
https://doi.org/10.1002/jcb.21785
https://doi.org/10.1002/jcb.21785
Autor:
Linda Sequeira, Carlton R. Cooper, Kenneth L. van Golen, Tracy A. Riesenberger, Cara W. Dubyk
Publikováno v:
Clinical & Experimental Metastasis. 25:569-579
Background The Rho GTPases comprise one of the eight subfamilies of the Ras superfamily of monomeric GTP-binding proteins and are involved in cytoskeletal organization. Previously, using a dominant negative construct, we demonstrated a role for RhoC
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df54ece16a18f08fa8305327a2c487b7
https://doi.org/10.1007/s10585-008-9173-3
https://doi.org/10.1007/s10585-008-9173-3