Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Carlotta Zampieri"'
Autor:
Elisabetta Mantuano, Carlotta Zampieri, Pardis Azmoon, Cory B. Gunner, Kyle R. Heye, Steven L. Gonias
Publikováno v:
JCI Insight, Vol 8, Iss 15 (2023)
Low-density lipoprotein receptor-related protein-1 (LRP1) functions as a receptor for nonpathogenic cellular prion protein (PrPC), which is released from cells by ADAM (a disintegrin and metalloproteinase domain) proteases or in extracellular vesicle
Externí odkaz:
https://doaj.org/article/afe55472c9374d5caabfd913552ed274
Autor:
Alessio Butera, Micaela Roy, Carlotta Zampieri, Eleonora Mammarella, Emanuele Panatta, Gerry Melino, Angelo D’Alessandro, Ivano Amelio
Publikováno v:
Biology Direct, Vol 17, Iss 1, Pp 1-11 (2022)
Abstract Adaptation of the lipid metabolism participates in cancer pathogenesis, facilitating energy storage and influencing cell fate and control of molecular signalling. The tumour suppressor protein p53 is a molecular hub of cell metabolism, suppo
Externí odkaz:
https://doaj.org/article/7b593b1a27d3489d9d5f824eebb22219
Autor:
Carlotta Zampieri, Emanuele Panatta, Vincenzo Corbo, Alessandro Mauriello, Gerry Melino, Ivano Amelio
Publikováno v:
Molecular Oncology, Vol 16, Iss 6, Pp 1259-1271 (2022)
Somatic inactivation of p53 (TP53) mainly occurs as missense mutations that lead to the acquisition of neomorphic mutant protein forms. p53 mutants have been postulated to exert gain‐of‐function (GOF) effects, including promotion of metastasis an
Externí odkaz:
https://doaj.org/article/c397b1b0a18e4067967c4668d43e2590
Publikováno v:
Biology Direct, Vol 16, Iss 1, Pp 1-9 (2021)
Abstract Most inactivating mutations in TP53 gene generates neomorphic forms of p53 proteins that experimental evidence and clinical observations suggest to exert gain-of-function effects. While massive effort has been deployed in the dissection of w
Externí odkaz:
https://doaj.org/article/49fd890b17c44ce2978e27086c7e5a0d
Publikováno v:
Biology Direct, Vol 16, Iss 1, Pp 1-7 (2021)
Abstract The mutation of TP53 gene affects half of all human cancers, resulting in impairment of the regulation of several cellular functions, including cell cycle progression and cell death in response to genotoxic stress. In the recent years additi
Externí odkaz:
https://doaj.org/article/0231091440674c1a99aae5fbc7ab5140
Autor:
Paola Pontecorvi, Michael A. Banki, Carlotta Zampieri, Cristina Zalfa, Pardis Azmoon, Maria Z. Kounnas, Cinzia Marchese, Steven L. Gonias, Elisabetta Mantuano
Publikováno v:
Journal of Neuroinflammation, Vol 16, Iss 1, Pp 1-14 (2019)
Abstract Background Astrocytes contribute to the crosstalk that generates chronic neuro-inflammation in neurological diseases; however, compared with microglia, astrocytes respond to a more limited continuum of innate immune system stimulants. Recent
Externí odkaz:
https://doaj.org/article/c67ad0f1890e467e9e9e93cdbf827933
Autor:
Cory B. Gunner, Pardis Azmoon, Elisabetta Mantuano, Lipsa Das, Carlotta Zampieri, Salvatore V. Pizzo, Steven L. Gonias
Publikováno v:
Journal of Cellular Biochemistry. 124:743-752
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e6110e1f44dec6b644963ad1727be094
https://doi.org/10.1002/jcb.30401
https://doi.org/10.1002/jcb.30401
Autor:
Steven L. Gonias, Carlotta Zampieri
Publikováno v:
Current drug targets, vol 21, iss 7
The major proteases that constitute the fibrinolysis system are tightly regulated. Protease inhibitors target plasmin, the protease responsible for fibrin degradation, and the proteases that convert plasminogen into plasmin, including tissue-type pla
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cfa4be19ec1598d83e71e1169dbce024
https://doi.org/10.2174/1389450120666191122101658
https://doi.org/10.2174/1389450120666191122101658
Publikováno v:
Biology Direct, Vol 16, Iss 1, Pp 1-7 (2021)
Biology Direct
Biology Direct
The mutation of TP53 gene affects half of all human cancers, resulting in impairment of the regulation of several cellular functions, including cell cycle progression and cell death in response to genotoxic stress. In the recent years additional p53-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8da8347e5eecffff385419553138edd7
http://hdl.handle.net/2108/294209
http://hdl.handle.net/2108/294209
Publikováno v:
Cell Death & Disease. 11
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1f2fc8f68d9ac9d17141b9aef7444654
https://doi.org/10.1038/s41419-020-2465-5
https://doi.org/10.1038/s41419-020-2465-5