Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Carlotta Petti"'
Autor:
Marialuisa Sensi, Andrea Anichini, Soldano Ferrone, Claudia Vegetti, Alessandra Molla, Carlotta Petti
Supplementary Table 1 from Coexpression of NRASQ61R and BRAFV600E in Human Melanoma Cells Activates Senescence and Increases Susceptibility to Cell-Mediated Cytotoxicity
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0725815f768809ae7603604cdc6731ef
https://doi.org/10.1158/0008-5472.22364394.v1
https://doi.org/10.1158/0008-5472.22364394.v1
Autor:
Marialuisa Sensi, Andrea Anichini, Soldano Ferrone, Claudia Vegetti, Alessandra Molla, Carlotta Petti
Supplementary Figures 1-3 from Coexpression of NRASQ61R and BRAFV600E in Human Melanoma Cells Activates Senescence and Increases Susceptibility to Cell-Mediated Cytotoxicity
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::728d2f47ab7e7d7f07f6ace768db1c2e
https://doi.org/10.1158/0008-5472.22364397.v1
https://doi.org/10.1158/0008-5472.22364397.v1
Autor:
Carlotta Petti, Kirsty J. Mustard, Claudia Vegetti, Loredana Cleris, Ilaria Bersani, Andrea Anichini, Franca Formelli, Grahame Hardie, Alessandra Molla, Marialuisa Sensi
Publikováno v:
Melanoma Research. 22:341-350
Raf/MEK/ERK signaling can inhibit the liver kinase B1-AMP-activated protein kinase (LKB1-AMPK) pathway, thus rendering melanoma cells resistant to energy stress conditions. We evaluated whether pharmacological reactivation of the AMPK function could
Autor:
Peter W. Gunning, Shane P. Whittaker, Galina Schevzov, Chin-Yi Kan, Karen L. MacKenzie, Michelle F. Maritz, Jason D. Coombes, Carlotta Petti
Publikováno v:
Cellular and Molecular Biology Letters. 20
Extensive re-organisation of the actin cytoskeleton and changes in the expression of its binding proteins is a characteristic feature of cancer cells. Previously we have shown that the tropomyosin isoform Tpm3.1, an integral component of the actin cy
Autor:
Soldano Ferrone, Marialuisa Sensi, Carlotta Petti, Andrea Anichini, Claudia Vegetti, Alessandra Molla
Publikováno v:
Cancer Research. 66:6503-6511
Activating mutations in BRAF and NRAS oncogenes in human melanomas are mutually exclusive. This finding has suggested an epistatic relationship but is consistent even with synthetic lethality. To evaluate the latter possibility, a mutated NRASQ61R on
Autor:
Jun Yuan, Ning Xu, Karen L. MacKenzie, Rosemary O'Brien, Richard B. Lock, Carlotta Petti, Chen Yang, Tao Liu, Chin-Yi Kan, Michelle F. Maritz, Lauryn S. Bracken
Publikováno v:
The Journal of biological chemistry. 288(17)
Survivin is an essential component of the chromosomal passenger complex and a member of the inhibitor of apoptosis family. It is expressed at high levels in a large variety of malignancies, where it has been implicated in drug resistance. It was also
Autor:
Nancy B. Amaro-Mugridge, Scott T. Pattison, Jocelyn Madrid-Weiss, Leo Phillips, Robert M. Graham, Bruce Stillman, Himanshu Brahmbhatt, Carlotta Petti, Stefanie Wetzel, Ilya Sedliarou, Kartini Kochar, Jennifer A. MacDiarmid, Vatsala N. Brahmbhatt
Publikováno v:
Nature biotechnology. 27(7)
The dose-limiting toxicity of chemotherapeutics, heterogeneity and drug resistance of cancer cells, and difficulties of targeted delivery to tumors all pose daunting challenges to effective cancer therapy. We report that small interfering RNA (siRNA)
Autor:
Carlotta Petti, Bracken Lauryn, Jun Yuan, Chin-Yi Kan, Ning Xu, Tao Liu, Philipp A. Dietrich, Karen L. MacKenzie
Publikováno v:
Cancer Research. 72:2196-2196
Survivin is an essential component of the chromosomal passenger complex and a member of the Inhibitor of Apoptosis (IAP) family. It is expressed at high levels in a large variety of malignancies, where it is implicated in cytoprotection and drug resi