Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Carlotta B. Jackson"'
Publikováno v:
European journal of pharmacology. 192(3)
In ferrets, the oral emetic activity of zacopride was compared with its R- and S-enantiomers. Increasing doses of 0.01, 0.1, 1.0, 10.0 and 31.6 mg/kg of zacopride or its 2 enantiomers were each administered at hourly intervals to separate groups of a
Publikováno v:
European journal of pharmacology. 181(3)
Zacopride administered orally was more emetic in fed than in fasted ferrets. The emetic activity of zacopride (0.1 mg/kg p.o.) was inhibited (100%) by 0.1 mg/kg i.p. of zacopride and 1 mg/kg i.p. of ICS 205–930. Haloperidol (3.16 mg/kg i.p.) and pr
Publikováno v:
Journal of Pharmacy and Pharmacology. 41:101-105
The antiemetic activity of zacopride against a variety of emetogenic agents has been determined in dogs. Zacopride was highly effective in inhibiting emesis due to a wide range of cancer chemotherapeutic agents, particularly cisplatin. It was well ab