Zobrazeno 1 - 10
of 220
pro vyhledávání: '"Carlotta, Giorgi"'
Autor:
Irene Dell’Anno, Federica Morani, Simone Patergnani, Antonio Daga, Paolo Pinton, Carlotta Giorgi, Luciano Mutti, Federica Gemignani, Stefano Landi
Publikováno v:
Cancer Cell International, Vol 24, Iss 1, Pp 1-11 (2024)
Abstract Background Malignant Pleural Mesothelioma (MPM) is a rare malignancy with a poor prognosis. Current therapies are unsatisfactory and novel cures are urgently needed. In a previous drug screening, we identified thonzonium bromide (TB) as one
Externí odkaz:
https://doaj.org/article/9e39a12c4d36447294cc9a0d363b6fd7
Autor:
Esther Densu Agyapong, Gaia Pedriali, Daniela Ramaccini, Esmaa Bouhamida, Elena Tremoli, Carlotta Giorgi, Paolo Pinton, Giampaolo Morciano
Publikováno v:
Journal of Translational Medicine, Vol 22, Iss 1, Pp 1-13 (2024)
Abstract Acute myocardial infarction (AMI) is a serious condition that occurs when part of the heart is subjected to ischemia episodes, following partial or complete occlusion of the epicardial coronary arteries. The resulting damage to heart muscle
Externí odkaz:
https://doaj.org/article/3718a08fe980456aaf1f78d3374639c5
Autor:
Bianca Vezzani, Mariasole Perrone, Marianna Carinci, Laura Palumbo, Alberto Tombolato, Denis Tombolato, Claudio Daminato, Valentina Gentili, Roberta Rizzo, Gianluca Campo, Luca Morandi, Alberto Papi, Savino Spadaro, Paolo Casolari, Marco Contoli, Paolo Pinton, Carlotta Giorgi
Publikováno v:
Journal of Inflammation, Vol 20, Iss 1, Pp 1-11 (2023)
Abstract Background The recent pandemic outbursts, due to SARS-CoV-2, have highlighted once more the central role of the inflammatory process in the propagation of viral infection. The main consequence of COVID-19 is the induction of a diffuse pro-in
Externí odkaz:
https://doaj.org/article/c313828e219b41b699cb347612cd75fa
Autor:
Anna Tarocco, Giampaolo Morciano, Mariasole Perrone, Claudia Cafolla, Cristina Ferrè, Tiziana Vacca, Ginevra Pistocchi, Fabio Meneghin, Ilaria Cocchi, Gianluca Lista, Irene Cetin, Pantaleo Greco, Giampaolo Garani, Marcello Stella, Miria Natile, Gina Ancora, Immacolata Savarese, Francesca Campi, Iliana Bersani, Andrea Dotta, Eloisa Tiberi, Giovanni Vento, Elisabetta Chiodin, Alex Staffler, Eugenia Maranella, Sandra Di Fabio, Mariusz R. Wieckowski, Carlotta Giorgi, Paolo Pinton
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-9 (2022)
Abstract Brain injury at birth is an important cause of neurological and behavioral disorders. Hypoxic-ischemic encephalopathy (HIE) is a critical cerebral event occurring acutely or chronically at birth with high mortality and morbidity in newborns.
Externí odkaz:
https://doaj.org/article/fb5537dd1b644e8ba12f06a5995fe12b
Autor:
Laura Palumbo, Marianna Carinci, Annunziata Guarino, Laila Asth, Silvia Zucchini, Sonia Missiroli, Alessandro Rimessi, Paolo Pinton, Carlotta Giorgi
Publikováno v:
Biomedicines, Vol 11, Iss 10, p 2825 (2023)
Neuroinflammation represents a dynamic process of defense and protection against the harmful action of infectious agents or other detrimental stimuli in the central nervous system (CNS). However, the uncontrolled regulation of this physiological proc
Externí odkaz:
https://doaj.org/article/35a28d26c0a341e4a0ce617dd94f50be
Autor:
David Liang, Liping Jiang, Sameer Ahmed Bhat, Sonia Missiroli, Mariasole Perrone, Angela Lauriola, Ritika Adhikari, Anish Gudur, Zahra Vasi, Ian Ahearn, Daniele Guardavaccaro, Carlotta Giorgi, Mark Philips, Shafi Kuchay
Publikováno v:
Cell Reports, Vol 42, Iss 1, Pp 111999- (2023)
Summary: Substrate degradation by the ubiquitin proteasome system (UPS) in specific membrane compartments remains elusive. Here, we show that the interplay of two lipid modifications and PDE6δ regulates compartmental substrate targeting via the SCFF
Externí odkaz:
https://doaj.org/article/d663d5a395244e3bab84b46f3f717660
Autor:
Gaia Pedriali, Daniela Ramaccini, Esmaa Bouhamida, Mariusz R. Wieckowski, Carlotta Giorgi, Elena Tremoli, Paolo Pinton
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 10 (2022)
Cardiovascular disease is the most common cause of death worldwide and in particular, ischemic heart disease holds the most considerable position. Even if it has been deeply studied, myocardial ischemia-reperfusion injury (IRI) is still a side-effect
Externí odkaz:
https://doaj.org/article/d180767971644109924df195ded2fab2
Autor:
Giampaolo Morciano, Alessandro Rimessi, Simone Patergnani, Veronica A.M. Vitto, Alberto Danese, Asrat Kahsay, Laura Palumbo, Massimo Bonora, Mariusz R. Wieckowski, Carlotta Giorgi, Paolo Pinton
Publikováno v:
Pharmacological Research, Vol 177, Iss , Pp 106119- (2022)
Intracellular calcium signaling is a universal language source shared by the most part of biological entities inside cells that, all together, give rise to physiological and functional anatomical units, the organ. Although preferentially recognized a
Externí odkaz:
https://doaj.org/article/d159d657b97142c29ffc2d5de738fd7e
Autor:
Elisa Mazzoni, Antonio D'Agostino, Maria Rosa Iaquinta, Ilaria Bononi, Lorenzo Trevisiol, John Charles Rotondo, Simone Patergnani, Carlotta Giorgi, Michael J. Gunson, G. William Arnett, Pier Francesco Nocini, Mauro Tognon, Fernanda Martini
Publikováno v:
Stem Cells Translational Medicine, Vol 9, Iss 3, Pp 377-388 (2020)
Abstract Tissue engineering‐based bone graft is an emerging viable treatment modality to repair and regenerate tissues damaged as a result of diseases or injuries. The structure and composition of scaffolds should modulate the classical osteogenic
Externí odkaz:
https://doaj.org/article/ff7bdbc9885740878f3ea89764155831
Autor:
Bianca Vezzani, Margherita Neri, Stefano D’Errico, Alberto Papi, Marco Contoli, Carlotta Giorgi
Publikováno v:
Pathogens, Vol 11, Iss 11, p 1390 (2022)
Two years after its spreading, the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is still responsible for more than 2000 deaths per day worldwide, despite vaccines and monoclonal antibody countermeasures. Therefore, there is a need to
Externí odkaz:
https://doaj.org/article/99c52d2764af4bc5a8af3c882bea3165