Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Carlota A Garcia-Dominguez"'
Autor:
Gonzalo Leon, Lucia Sanchez-Ruiloba, Andrea Perez-Rodriguez, Teresa Gragera, Natalia Martinez, Silvia Hernandez, Berta Anta, Olga Calero, Carlota A Garcia-Dominguez, Lara M Dura, Daniel Peña-Jimenez, Judit Castro, Natasha Zarich, Pilar Sanchez-Gomez, Miguel Calero, Teresa Iglesias, Jose L Oliva, Jose M Rojas
Publikováno v:
PLoS ONE, Vol 9, Iss 12, p e114837 (2014)
The Shoc2 protein has been implicated in the positive regulation of the Ras-ERK pathway by increasing the functional binding interaction between Ras and Raf, leading to increased ERK activity. Here we found that Shoc2 overexpression induced sustained
Externí odkaz:
https://doaj.org/article/550a314de4ff45b7a1a7d285e8170e2b
Autor:
Carlota A García-Domínguez, Natalia Martínez, Teresa Gragera, Andrea Pérez-Rodríguez, Diana Retana, Gonzalo León, Agustín Sánchez, José Luis Oliva, Dolores Pérez-Sala, José M Rojas
Publikováno v:
PLoS ONE, Vol 6, Iss 2, p e16787 (2011)
Sprouty and Spred proteins have been widely implicated in the negative regulation of the fibroblast growth factor receptor-extracellular regulated kinase (ERK) pathway. In considering the functional role of these proteins, we explored their effects o
Externí odkaz:
https://doaj.org/article/48e19c28ab1c458eae1f03da80e9dcd9
Autor:
Clara L Oeste, Beatriz Díez-Dacal, Francesca Bray, Mario García de Lacoba, Beatriz G de la Torre, David Andreu, Antonio J Ruiz-Sánchez, Ezequiel Pérez-Inestrosa, Carlota A García-Domínguez, José M Rojas, Dolores Pérez-Sala
Publikováno v:
PLoS ONE, Vol 6, Iss 1, p e15866 (2011)
Ras proteins are crucial players in differentiation and oncogenesis and constitute important drug targets. The localization and activity of Ras proteins are highly dependent on posttranslational modifications at their C-termini. In addition to an iso
Externí odkaz:
https://doaj.org/article/712eb7985871462f8ee67f16db98aea7