Zobrazeno 1 - 10
of 41
pro vyhledávání: '"Carlos de Torre"'
Autor:
Fernando Lucas-Ruiz, Sandra V. Mateo, Marta Jover-Aguilar, Felipe Alconchel, Laura Martínez-Alarcón, Carlos de Torre-Minguela, Daniel Vidal-Correoso, Francisco Villalba-López, Víctor López-López, Antonio Ríos-Zambudio, José A. Pons, Pablo Ramírez, Pablo Pelegrín, Alberto Baroja-Mazo
Publikováno v:
EBioMedicine, Vol 87, Iss , Pp 104419- (2023)
Summary: Background: Innate immunity plays a fundamental role in solid organ transplantation. Myeloid cells can sense danger signals or DAMPs released after tissue or cell damage, such as during ischemia processes. This study aimed to identify DAMPs
Externí odkaz:
https://doaj.org/article/2c28ea19bada4e2e8e37f7e5119246df
Autor:
Claudia Giménez-Campillo, Juan de Dios Hernández, Isidro Guillén, Natalia Campillo, Natalia Arroyo-Manzanares, Carlos de Torre-Minguela, Pilar Viñas
Publikováno v:
Foods, Vol 11, Iss 24, p 4055 (2022)
The nitrosyl–heme complex is considered the pigment responsible for the development of reddish colour in cooked hams. However, the same reddish colour was observed in a nitrite-free product elaborated with polyphenols, suggesting the presence of ot
Externí odkaz:
https://doaj.org/article/bd9e7db05d4c47eba4209faa7f84b453
Autor:
Victor López-López, Fernando Pérez-Sánz, Carlos de Torre-Minguela, Josefa Marco-Abenza, Ricardo Robles-Campos, Francisco Sánchez-Bueno, José A. Pons, Pablo Ramírez, Alberto Baroja-Mazo
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
BackgroundAlthough proteomics has been employed in the study of several models of liver injury, proteomic methods have only recently been applied not only to biomarker discovery and validation but also to improve understanding of the molecular mechan
Externí odkaz:
https://doaj.org/article/ba90ee09e5eb4769b8add215ef669012
Autor:
Juan José Martínez-García, Helios Martínez-Banaclocha, Diego Angosto-Bazarra, Carlos de Torre-Minguela, Alberto Baroja-Mazo, Cristina Alarcón-Vila, Laura Martínez-Alarcón, Joaquín Amores-Iniesta, Fátima Martín-Sánchez, Giovanni A. Ercole, Carlos M. Martínez, Ada González-Lisorge, José Fernández-Pacheco, Piedad Martínez-Gil, Sahil Adriouch, Friedrich Koch-Nolte, Juan Luján, Francisco Acosta-Villegas, Pascual Parrilla, Carlos García-Palenciano, Pablo Pelegrin
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-14 (2019)
Systemic sepsis is a potentially life-threatening illness and immunocompromised individuals are especially vulnerable. Here, using a cohort of patients with intra-abdominal origin sepsis, the authors show an important role for the NLRP3 inflammasome
Externí odkaz:
https://doaj.org/article/1ae90a92ab1d45b3b618703a201c9c3b
Autor:
Cristina Alarcón-Vila, Alberto Baroja-Mazo, Carlos de Torre-Minguela, Carlos M Martínez, Juan J Martínez-García, Helios Martínez-Banaclocha, Carlos García-Palenciano, Pablo Pelegrin
Publikováno v:
eLife, Vol 9 (2020)
P2X7 receptor activation induces the release of different cellular proteins, such as CD14, a glycosylphosphatidylinositol (GPI)-anchored protein to the plasma membrane important for LPS signaling via TLR4. Circulating CD14 has been found at elevated
Externí odkaz:
https://doaj.org/article/860ef86d817641659a509d5f0529c7ab
Autor:
Laura Martínez-Alarcón, Sergio Liarte, Juan J. Quereda, Aida Sáez-Acosta, Carlos de Torre-Minguela, Livia Mendonça, Juana M. Abellaneda, María J. Majado, Antonio Ríos, Pablo Ramírez, Antonio Muñoz, Guillermo Ramis
Publikováno v:
Biology, Vol 10, Iss 8, p 747 (2021)
Xenotransplantation of pig organs receives substantial attention for being comparable to human’s. However, compatibility constraints involving hyper-acute rejection (HAR) still block clinical applications. Transgenesis of human complement regulator
Externí odkaz:
https://doaj.org/article/39c10ed32443406b8378cf5d12b0d5d9
Autor:
Leticia Mayor-López, Elena Tristante, Mar Carballo-Santana, Estefanía Carrasco-García, Silvina Grasso, Pilar García-Morales, Miguel Saceda, Juan Luján, José García-Solano, Fernando Carballo, Carlos de Torre, Isabel Martínez-Lacaci, PhD
Publikováno v:
Translational Oncology, Vol 7, Iss 5, Pp 590-604 (2014)
The use of heat shock protein 90 (Hsp90) inhibitors is an attractive antineoplastic therapy. We wanted to compare the effects of the benzoquinone 17-allylamino-17-demethoxygeldanamycin (17-AAG, tanespimycin) and the novel isoxazole resorcinol–based
Externí odkaz:
https://doaj.org/article/9569dd5d0753487a8b725daec68fab77
Autor:
Maria Barberà-Cremades, Ana I. Gómez, Alberto Baroja-Mazo, Laura Martínez-Alarcón, Carlos M. Martínez, Carlos de Torre-Minguela, Pablo Pelegrín
Publikováno v:
Frontiers in Immunology, Vol 8 (2017)
Tumor necrosis factor (TNF)-α is a major pro-inflammatory cytokine produced in response to toll-like receptor stimulation. TNF-α release is controlled by the activity of TNF-α converting enzyme (TACE) that cut membrane-bound TNF-α to shed its ect
Externí odkaz:
https://doaj.org/article/dadf569dab0e4e55b9641606168d572b
Autor:
Alberto Baroja‐Mazo, Alejandro Peñín‐Franch, Fernando Lucas‐Ruiz, Carlos de Torre‐Minguela, Cristina Alarcón‐Vila, Trinidad Hernández‐Caselles, Pablo Pelegrín
Publikováno v:
British Journal of Pharmacology
A high number of intratumoural infiltrating natural killer (NK) cells is associated with better survival in several types of cancer, constituting an important first line of defence against tumours. Hypoxia in the core of solid tumours induces cellula
Autor:
Claudia Giménez-Campillo, Natalia Campillo, Natalia Arroyo-Manzanares, Carlos M. Martínez, Carlos de Torre Minguela, Pilar Viñas
Epidemiological studies have shown that haem iron from processed meat is a key element involved in the colon carcinogenesis. The haem iron induces lipid peroxidation in the colon lumen during digestion, enabling the formation of cytotoxic molecules d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9db847ed269075d39d9f246f5d0d342c
https://doi.org/10.21203/rs.3.rs-2975976/v1
https://doi.org/10.21203/rs.3.rs-2975976/v1