Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Carlos W S Wanderley"'
Autor:
Deysi V T Wong, Roberto C P Lima-Júnior, Cibele B M Carvalho, Vanessa F Borges, Carlos W S Wanderley, Amanda X C Bem, Caio A V G Leite, Maraiza A Teixeira, Gabriela L P Batista, Rangel L Silva, Thiago M Cunha, Gerly A C Brito, Paulo R C Almeida, Fernando Q Cunha, Ronaldo A Ribeiro
Publikováno v:
PLoS ONE, Vol 10, Iss 10, p e0139985 (2015)
Intestinal mucositis is a common side effect of irinotecan-based anticancer regimens. Mucositis causes cell damage, bacterial/endotoxin translocation and production of cytokines including IL-1 and IL-18. These molecules and toll-like receptors (TLRs)
Externí odkaz:
https://doaj.org/article/70e4dd6593c243b0847fdb00138d362b
Autor:
Rodrigo de Oliveira Formiga, Flávia C. Amaral, Camila F. Souza, Daniel A. G. B. Mendes, Carlos W. S. Wanderley, Cristina B. Lorenzini, Adara A. Santos, Juliana Antônia, Lucas F. Faria, Caio C. Natale, Nicholas M. Paula, Priscila C. S. Silva, Fernanda R. Fonseca, Luan Aires, Nicoli Heck, Márick R. Starick, Celso M. Queiroz‐Junior, Felipe R. S. Santos, Filipe R. O. de Souza, Vivian V. Costa, Shana P. C. Barroso, Alexandre Morrot, Johan Van Weyenbergh, Regina Sordi, Frederico Alisson‐Silva, Fernando Q. Cunha, Edroaldo L. Rocha, Sylvie Chollet‐Martin, Maria Margarita Hurtado‐Nedelec, Clémence Martin, Pierre‐Régis Burgel, Daniel S. Mansur, Rosemeri Maurici, Matthew S. Macauley, André Báfica, Véronique Witko‐Sarsat, Fernando Spiller
Publikováno v:
British Journal of Pharmacology. 180:1460-1481
Neutrophil overstimulation plays a crucial role in tissue damage during severe infections. As pathogen-derived neuraminidase (NEU) stimulate neutrophils, we investigated whether host NEU can be targeted to regulate neutrophil dysregulation observed i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b5b285cfd525b34d12725501c315b79
https://doi.org/10.1111/bph.16013
https://doi.org/10.1111/bph.16013
Neuraminidase inhibitors rewire neutrophil function in vivo in murine sepsis and ex vivo in COVID-19
Autor:
Rodrigo de Oliveira Formiga, Flávia C. Amaral, Camila F. Souza, Daniel A. G. B. Mendes, Carlos W. S. Wanderley, Cristina B. Lorenzini, Adara A. Santos, Juliana Antônia, Lucas F. Faria, Caio C. Natale, Nicholas M. Paula, Priscila C. S. Silva, Fernanda R. Fonseca, Luan Aires, Nicoli Heck, Márick R. Starick, Celso M. Queiroz-Junior, Felipe R. S. Santos, Filipe R. O. de Souza, Vivian V. Costa, Shana P. C. Barroso, Alexandre Morrot, Johan Van Weyenbergh, Regina Sordi, Frederico Alisson-Silva, Fernando Q. Cunha, Edroaldo L. Rocha, Sylvie Chollet-Martin, Maria Margarita Hurtado-Nedelec, Clémence Martin, Pierre-Régis Burgel, Daniel S. Mansur, Rosemeri Maurici, Matthew S. Macauley, André Báfica, Véronique Witko-Sarsat, Fernando Spiller
Publikováno v:
bioRxiv
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Neutrophil overstimulation plays a crucial role in tissue damage during severe infections. Neuraminidase (NEU)-mediated cleavage of surface sialic acid has been demonstrated to regulate leukocyte responses. Here, we report that antiviral NEU inhibito
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f7e80654188358ad8cc60996af3801d8
https://europepmc.org/articles/PMC9641843/
https://europepmc.org/articles/PMC9641843/
Autor:
Fernando Q. Cunha, Carlos W. S. Wanderley, Carlos Hiroji Hiroki, Camilla Meireles S Silva, Augusto V. Gonçalves, Gustavo Fernando da Silva Quirino, Guilherme Cesar Martelossi Cebinelli, Marcos Henrique Rosa, Thiago M. Cunha, Dario S. Zamboni, Jessica Adrielle Teixeira Santos, José-Carlos A Filho, Mikhael Haruo Fernandes de Lima, Vanessa F. Borges
Publikováno v:
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Universidade de São Paulo (USP)
instacron:USP
Background Although the literature shows that an increase in both the number and suppressive function of CD4+forkhead box P3 (FOXP3)+ T-regulatory cells (Tregs) during sepsis contributes to an immunosuppressed state, little is known about the identit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::003a7d4437cf84e89e63682a8fd123f0
Autor:
Katiussia P Silva, David F. Colón, Valter Vinicius Silva Monteiro, Juliana E Toller-Kawahisa, Vanessa F. Borges, Fausto Almeida, Thiago M. Cunha, Helder I. Nakaya, Marcos C. Borges, José C. Alves-Filho, Verônica Soares Brauer, Dario S. Zamboni, Camila Meirelles de Souza Silva, Daniele C. Nascimento, Carlos W. S. Wanderley, Flávio P. Veras, Sabrina Setembre Batah, Luis Eduardo Alves Damasceno, Ana Letícia J Souza, Fabiane Sônego, Fernando Q. Cunha, Augusto V. Gonçalves, Paula B. Donate, Timna Varela Martins, Alexandre Todorovic Fabro, Antonio Edson Rocha Oliveira, Daniel Zoppi
Publikováno v:
Scopus
Repositório Institucional da UNESP
Universidade Estadual Paulista (UNESP)
instacron:UNESP
Blood
Repositório Institucional da UNESP
Universidade Estadual Paulista (UNESP)
instacron:UNESP
Blood
Made available in DSpace on 2022-04-29T08:46:05Z (GMT). No. of bitstreams: 0 Previous issue date: 2021-12-23 Multiple organ dysfunction is the most severe outcome of sepsis progression and is highly correlated with a worse prognosis. Excessive neutro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a30566c0b2469ec4cfcbed4a36e2fad
Autor:
Fernando Q. Cunha, Ellen Nascimento, Saulo Silva, Gilberto de Castro, Jose Flavio Marin, Mariana De Macedo, Carlos W. S. Wanderley, Fernanda Antonacio
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss Suppl 2 (2021)
BackgroundTumor metabolic remodeling is considered one of the hallmarks of cancers and has been implicated in immune evasion. Highly glycolytic tumors can lead to immune suppression by both nutrient competition and toxic metabolite accumulation. Immu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::541ced361cd518b692996defa3a7218c
https://doaj.org/article/5a196b0a82df45129771701dd5c640bf
https://doaj.org/article/5a196b0a82df45129771701dd5c640bf
Autor:
Celuane Alves Moura, Larissa Araújo Rolim, Juliana Mikaely Dias Soares, Raimundo C. Palheta-Junior, Helinando P. de Oliveira, Raimundo Gonçalves de Oliveira-Júnior, Jackson Roberto Guedes da Silva Almeida, Carlos W. S. Wanderley, Anita E.A.S. Ribeiro, Emmanoel V. Costa, Ana Paula de Oliveira, Helder Anderson Lima Silva
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 111, Iss, Pp 1046-1056 (2019)
Background Bothropic venoms cause intense local damage, pain, edema, and myonecrosis. Morus nigra L. (Moraceae) has several uses in folk medicine and can be a promising candidate for the treatment of several inflammatory disorders. Hypothesis/Purpose
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::599fd7a59946a35b3a92f039a763504f
https://doi.org/10.1016/j.biopha.2019.01.011
https://doi.org/10.1016/j.biopha.2019.01.011
Autor:
G. De Castro, Carlos W. S. Wanderley, F.F. Antonacio, M.P. de Macedo, S.B. Silva, J.F.G. Marin, Fernando Q. Cunha, E.C.T. do Nascimento
Publikováno v:
Annals of Oncology. 32:S846-S847
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8231dac275d2a181900c558df486c2ca
https://doi.org/10.1016/j.annonc.2021.08.1377
https://doi.org/10.1016/j.annonc.2021.08.1377
Autor:
Jose Mauricio Mota, Kalil Alves de Lima, Fernando Q. Cunha, Roberto C. P. Lima-Júnior, Maria Dirlei Begnami, Vinicius Kannen, Leticia Almeida Nascimento, Carlos W. S. Wanderley, Caio Abner Leite, José C. Alves-Filho, Ronaldo A. Ribeiro, Marcela Davoli Ferreira, Paula Ramos Viacava, David F. Colón, Vladmir Cláudio Cordeiro de Lima, Camila Meirelles de Souza Silva, Juliana Yumi Sakita
Publikováno v:
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Journal for Immunotherapy of Cancer
Universidade de São Paulo (USP)
instacron:USP
Journal for Immunotherapy of Cancer
BackgroundPrevious data have reported that the growth of established tumors may be facilitated by postsepsis disorder through changes in the microenvironment and immune dysfunction. However, the influence of postsepsis disorder in initial carcinogene
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::595e1dfec8c25c7dd0e206e7d5afbe3f
Autor:
Susanne Schmidt, Eicke Latz, Salie Maasewerd, Lisa Böttcher, Maximilian Rothe, Tomasz Próchnicki, Carlos W. S. Wanderley, Nathalia Rosero, Camila Meirelles de Souza Silva, H. James Stunden, Marina L. S. Santos, Bernardo S. Franklin, Fernando Q. Cunha, Verena Rolfes, Ibrahim Hawwari, Damien Bertheloot, Luzia H. Carvalho, Cor Jesus Fernandes Fontes, Moshe Arditi, Lucas S. Ribeiro, Magali Noval Rivas
Publikováno v:
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Cell Reports
Cell reports 31(6), 107615 (2020). doi:10.1016/j.celrep.2020.107615
Universidade de São Paulo (USP)
instacron:USP
Cell Reports
Cell reports 31(6), 107615 (2020). doi:10.1016/j.celrep.2020.107615
Summary The inflammasomes control the bioactivity of pro-inflammatory cytokines of the interleukin (IL)-1 family. The inflammasome assembled by NLRP3 has been predominantly studied in homogeneous cell populations in vitro, neglecting the influence of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cf46fea8224287b23af43f8deba67971