Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Carlos Vela-Rodríguez"'
Autor:
Carlos Vela-Rodríguez, Lari Lehtiö
Publikováno v:
Biochemical Society Transactions. 50:1683-1692
Ubiquitination is a protein post-translational modification that affects protein localisation, stability and interactions. E3 ubiquitin ligases regulate the final step of the ubiquitination reaction by recognising target proteins and mediating the ub
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::23dc5d7d5225ee251b4805b518df536c
https://doi.org/10.1042/bst20220501
https://doi.org/10.1042/bst20220501
DTX3L and USP28 fine-tune DNA double strand repair through mutual regulation of their protein levels
Autor:
Yashwanth Ashok, Daniela Mennerich, Carlos Vela-Rodríguez, Heli I. Alanen, Melanie Rall-Scharpf, Lisa Wiesmüller, Renata Prunskaite-Hyyryläinen, Lari Lehtiö, Thomas Kietzmann
The DNA damage response involves a complex protein network with members mediating different post-translational modifications such as ubiquitination and deubiquitination. Thereby the E3 ubiquitin ligase DTX3L as well as the deubiquitinase USP28 are re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d009846c2fe6abd4155517a3392094fd
https://doi.org/10.1101/2023.01.30.526213
https://doi.org/10.1101/2023.01.30.526213
Autor:
Yashwanth Ashok, Carlos Vela-Rodríguez, Chunsong Yang, Heli I. Alanen, Fan Liu, Bryce M. Paschal, Lari Lehtiö
Publikováno v:
The Biochemical journal. 479(3)
Ubiquitination and ADP-ribosylation are post-translational modifications that play major roles in pathways including the DNA damage response and viral infection. The enzymes responsible for these modifications are therefore potential targets for ther
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b3a88869bbd971d656303112211baa60
https://pubmed.ncbi.nlm.nih.gov/35037691
https://pubmed.ncbi.nlm.nih.gov/35037691
Autor:
Albert Galera-Prat, Alexander Ignatev, Mariana Cázares-Olivera, Carlos Vela-Rodríguez, Lari Lehtiö, Sven T. Sowa, Renata Prunskaite-Hyyryläinen
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-12 (2020)
Scientific Reports
Scientific Reports
Tankyrases catalyse poly-ADP-ribosylation of their binding partners and the modification serves as a signal for the subsequent proteasomal degradation of these proteins. Tankyrases thereby regulate the turnover of many proteins involved in multiple a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::84101608008c575b15d349e2c7b5d6e3
http://urn.fi/urn:nbn:fi-fe2020120299038
http://urn.fi/urn:nbn:fi-fe2020120299038