Zobrazeno 1 - 10
of 201
pro vyhledávání: '"Carlos Sonnenschein"'
Autor:
Carlos Sonnenschein, Ana M Soto
Publikováno v:
PLoS Biology, Vol 18, Iss 4, p e3000670 (2020)
Despite over a century of intensive efforts, the great gains promised by the War on Cancer nearly 50 years ago have not materialized. Since 1999, we have analyzed the lack of progress in explaining and "curing" cancer by examining the merits of the p
Externí odkaz:
https://doaj.org/article/d84b913feb8546d0be4e73b21632c229
Publikováno v:
Cancer Cell International, Vol 18, Iss 1, Pp 1-12 (2018)
Abstract Background Three-dimensional cultures of mammary epithelial cells allow for biologically-relevant studies of the development of the mammary gland in rodents and humans under normal and pathological conditions, like carcinogenesis. Under thes
Externí odkaz:
https://doaj.org/article/91c0617a72a34f2fa4b783f24ba734e1
Autor:
Tessie Paulose, Maël Montévil, Lucia Speroni, Florent Cerruti, Carlos Sonnenschein, Ana M Soto
Publikováno v:
PLoS ONE, Vol 11, Iss 4, p e0153022 (2016)
Three-dimensional (3D) culture models are critical tools for understanding tissue morphogenesis. A key requirement for their analysis is the ability to reconstruct the tissue into computational models that allow quantitative evaluation of the formed
Externí odkaz:
https://doaj.org/article/1f40b92442d44905ba21be4c29236681
Autor:
Marie Tremblay-Franco, Nicolas J Cabaton, Cécile Canlet, Roselyne Gautier, Cheryl M Schaeberle, Fabien Jourdan, Carlos Sonnenschein, Florence Vinson, Ana M Soto, Daniel Zalko
Publikováno v:
PLoS ONE, Vol 10, Iss 10, p e0141698 (2015)
Along with the well-established effects on fertility and fecundity, perinatal exposure to endocrine disrupting chemicals, and notably to xeno-estrogens, is strongly suspected of modulating general metabolism. The metabolism of a perinatally exposed i
Externí odkaz:
https://doaj.org/article/ec144a6ab5944e06967473b89284f211
Autor:
Eugen Dhimolea, Perinaaz R Wadia, Tessa J Murray, Matthew L Settles, Jo D Treitman, Carlos Sonnenschein, Toshi Shioda, Ana M Soto
Publikováno v:
PLoS ONE, Vol 9, Iss 7, p e99800 (2014)
Exposure to environmental estrogens (xenoestrogens) may play a causal role in the increased breast cancer incidence which has been observed in Europe and the US over the last 50 years. The xenoestrogen bisphenol A (BPA) leaches from plastic food/beve
Externí odkaz:
https://doaj.org/article/230442f2a5604ccd9b4feb913d75a799
Autor:
Clifford Barnes, Lucia Speroni, Kyle P Quinn, Mael Montevil, Kurt Saetzler, Gbemisola Bode-Animashaun, George McKerr, Irene Georgakoudi, C Stephen Downes, Carlos Sonnenschein, C Vyvyan Howard, Ana M Soto
Publikováno v:
PLoS ONE, Vol 9, Iss 4, p e93325 (2014)
Mammary gland morphogenesis involves ductal elongation, branching, and budding. All of these processes are mediated by stroma--epithelium interactions. Biomechanical factors, such as matrix stiffness, have been established as important factors in the
Externí odkaz:
https://doaj.org/article/2c4dd9b937bc4e2c8b0c0f52d8c38446
Autor:
Perinaaz R Wadia, Nicolas J Cabaton, Michael D Borrero, Beverly S Rubin, Carlos Sonnenschein, Toshi Shioda, Ana M Soto
Publikováno v:
PLoS ONE, Vol 8, Iss 5, p e63902 (2013)
Exposure of rodent fetuses to low doses of the endocrine disruptor bisphenol A (BPA) causes subtle morphological changes in the prenatal mammary gland and results in pre-cancerous and cancerous lesions during adulthood. To examine whether the BPA-ind
Externí odkaz:
https://doaj.org/article/0d66171cd48b47e9af3132cda99c1eb1
Autor:
Ana M. Soto, Carlos Sonnenschein
Publikováno v:
Gaceta Sanitaria, Vol 16, Iss 3, Pp 209-211 (2002)
Externí odkaz:
https://doaj.org/article/1c1877fd8c8c418dbdd236be93295084
Autor:
Ana M. Soto, Carlos Sonnenschein
Publikováno v:
Biological Theory. 15:180-187
David Waldron Smithers was, among other things, a physician and a pioneer of cancer radiotherapy and a well-respected figure in British medicine and public health. From the 1940s until his retirement from medical practice in 1973, he was the director
Autor:
Ana M. Soto, Emma De Angelis, Carlos Sonnenschein, Denis Noble, Ali Hossaini, Raymond Noble, Kenneth Payne
Publikováno v:
The RUSI Journal. 164:120-144
Courtesy of Kirsty Pargeter/Adobe Stock Most of the contributions to this special issue on artificial intelligence (AI) look at the development of AI technologies within the realm of the possible, ...