Výsledky vyhledávání - "Carlos Saffie"

Supplementary Data from Heat-Shock Induction of Tumor-Derived Danger Signals Mediates Rapid Monocyte Differentiation into Clinically Effective Dendritic Cells

Autor: Flavio Salazar-Onfray, Mercedes N. López, Paola Garrido, Carlos Ferrada, Ariadna Mendoza-Naranjo, Marcela Hermoso, Arturo Ferreira, Lorena Salazar, Tamara García, Daniel Hevia, Cristián Pereda, Diego Reyes, Marcos Ramírez, Fermín E. González, Andrés Tittarelli, Carlos Saffie, Raquel Aguilera

Supplementary Figures S1-S4; Supplementary Table S1.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5aec6165b161c04802a69917f02ebdcf
https://doi.org/10.1158/1078-0432.22442501

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Data from Heat-Shock Induction of Tumor-Derived Danger Signals Mediates Rapid Monocyte Differentiation into Clinically Effective Dendritic Cells

Purpose: This study characterizes, biologically and clinically, a novel type of dendritic cells (DC) produced in the short term and called tumor antigen–presenting cells (TAPCells). In particular, we identified factors present in a lysate derived f

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a57e54e0538b7abcda8e15e84522c4f
https://doi.org/10.1158/1078-0432.c.6519215

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Toll-like receptor 4 gene polymorphism influences dendritic cell in vitro function and clinical outcomes in vaccinated melanoma patients

Autor: Andrés Tittarelli, Cristián Falcón, Carlos Saffie, Leonel Muñoz, Tamara Garcia, Gabriela Mora, Fermín E. González, David Diaz, Marcela A. Hermoso, Cristián Pereda, Flavio Salazar-Onfray, Mercedes N. López

Publikováno v: CANCER IMMUNOLOGY IMMUNOTHERAPY
Artículos CONICYT
CONICYT Chile
instacron:CONICYT

Toll-like receptor 4 (TLR4) is expressed on dendritic cells (DCs), sensing environmental danger molecules that induce their activation and maturation. Recently, we reported a method for the production of therapeutic DCs against melanoma, called tumor

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b608eeaf17eb4a41bfc46732a4ff6b4
https://doi.org/10.1007/s00262-012-1268-7

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Heat-shock induction of tumor-derived danger signals mediates rapid monocyte differentiation into clinically effective dendritic cells

Autor: Cristián Pereda, Carlos Saffie, Flavio Salazar-Onfray, Diego Reyes, Lorena Salazar, Carlos Ferrada, Tamara Garcia, Paola Garrido, Mercedes N. López, Marcos Ramírez, Ariadna Mendoza-Naranjo, Fermín E. González, Arturo Ferreira, Raquel Aguilera, Daniel Hevia, Marcela A. Hermoso, Andrés Tittarelli

Publikováno v: CLINICAL CANCER RESEARCH
Artículos CONICYT
CONICYT Chile
instacron:CONICYT

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b27fe161278dd8ddad6407554f276da
https://pubmed.ncbi.nlm.nih.gov/21292818

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Abstract B17: Heat shock-induced danger signals in tumor cells are crucial for a rapid differentiation of monocyte to therapeutic dendritic cells

Autor: Carlos Ferrada, Carlos Saffie, Fermín E. González, Diego Reyes, Flavio Salazar-Onfray, Andrés Tittarelli, Raquel Aguilera, Mercedes N. López

Publikováno v: Clinical Cancer Research. 16:B17-B17

Dendritic cells (DCs) are potent antigen-presenting cells (APCs) that initiate a cell-mediated antitumor immune response. Recently, we showed that monocyte-derived DCs loaded with a heat-shocked melanoma cell lysate (TRIMEL®) induce melanoma-specifi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::6fdc5891211a5d2e1cd5f8f90a3f640b
https://doi.org/10.1158/1078-0432.tcme10-b17

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