Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Carlos S. Kückelhaus"'
Autor:
Gustavo Adolfo Sierra Romero, Tatiana Karla dos Santos Borges, José Roberto S. A. Leite, Luciana M. Leite, Daniel C. Moreira, Selma A S Kuckelhaus, Maura V. Prates, Daniela Sant’Ana de Aquino, Carlos S. Kückelhaus, Maria Imaculada Muniz-Junqueira, Carlos Bloch
Publikováno v:
International Journal of Environmental Research and Public Health, Vol 17, Iss 4856, p 4856 (2020)
International Journal of Environmental Research and Public Health
Volume 17
Issue 13
Repositório Institucional da UnB
Universidade de Brasília (UnB)
instacron:UNB
Repositório Institucional da EMBRAPA (Repository Open Access to Scientific Information from EMBRAPA-Alice)
Empresa Brasileira de Pesquisa Agropecuária (Embrapa)
instacron:EMBRAPA
International Journal of Environmental Research and Public Health
Volume 17
Issue 13
Repositório Institucional da UnB
Universidade de Brasília (UnB)
instacron:UNB
Repositório Institucional da EMBRAPA (Repository Open Access to Scientific Information from EMBRAPA-Alice)
Empresa Brasileira de Pesquisa Agropecuária (Embrapa)
instacron:EMBRAPA
Leishmania protozoans are the causal agents of neglected diseases that represent an important public health issue worldwide. The growing occurrence of drug-resistant strains of Leishmania and severe side effects of available treatments represent an i
Publikováno v:
Experimental Parasitology. 127:658-664
The high toxicity of current drugs for treatment of leishmaniasis is a major hindrance for controlling the disease. Pravastatin is a well-known drug with anti-inflammatory and immunomodulatory properties that may modulate host defense mechanisms agai
Autor:
Carlos Eduardo Tosta, Selma A S Kuckelhaus, Maria Imaculada Muniz-Junqueira, Carlos S. Kückelhaus
Publikováno v:
Experimental parasitology. 134(1)
The control of leishmaniases poses an important challenge due to the scarcity and toxicity of the pharmacological options available. We have previously shown that pravastatin significantly improves the course of the disease in Leishmania (L.) amazone
Autor:
Ada Amalia Ayala Urdapilleta, Selma A S Kuckelhaus, Charlene Barreto Ponte, Maria Imaculada Muniz-Junqueira, Érica Alessandra Rocha Alves, Carlos S. Kückelhaus, Raimunda Nonata Ribeiro Sampaio
Publikováno v:
International Immunopharmacology. (1):114-119
Miltefosine is an anticancer drug currently used to treat visceral and cutaneous leishmaniasis, also presents a broad-spectrum of fungicidal and antiamoebae activities. It acts on the metabolism of phospholipids and glycoproteins of the membrane of p