Zobrazeno 1 - 10 of 16 pro vyhledávání: '"Carlos Ruíz-Martínez"'
1
Akademický článek
IGF1R deficiency attenuates acute inflammatory response in a bleomycin-induced lung injury mouse model
Autor: Sergio Piñeiro-Hermida, Icíar P. López, Elvira Alfaro-Arnedo, Raquel Torrens, María Iñiguez, Lydia Alvarez-Erviti, Carlos Ruíz-Martínez, José G. Pichel
Publikováno v: Scientific Reports, Vol 7, Iss 1, Pp 1-13 (2017)
Abstract IGF1R (Insulin-like Growth Factor 1 Receptor) is a tyrosine kinase with pleiotropic cellular functions. IGF activity maintains human lung homeostasis and is implicated in pulmonary diseases such as cancer, ARDS, COPD, asthma and fibrosis. He
Externí odkaz: https://doaj.org/article/3b2793cee94e4995ba43123296da8895
Zobrazit plný text záznamu
2
Akademický článek
Characterization of the acute inflammatory profile and resolution of airway inflammation after Igf1r-gene targeting in a murine model of HDM-induced asthma.
Autor: Sergio Piñeiro-Hermida, Elvira Alfaro-Arnedo, Joshua A Gregory, Raquel Torrens, Carlos Ruíz-Martínez, Mikael Adner, Icíar P López, José G Pichel
Publikováno v: PLoS ONE, Vol 12, Iss 12, p e0190159 (2017)
Asthma is a chronic inflammatory disease characterized by bronchial hyperresponsiveness, mucus overproduction and airway remodeling. Notably, we have recently demonstrated that insulin-like growth factor 1 receptor (IGF1R) deficiency in mice attenuat
Externí odkaz: https://doaj.org/article/af15676d209e4d1a9ee47fddd1eea8b3
Zobrazit plný text záznamu
3
IGF1R acts as a cancer-promoting factor in the tumor microenvironment facilitating lung metastasis implantation and progression
Autor: Elvira Alfaro-Arnedo, Icíar P. López, Sergio Piñeiro-Hermida, Marta Canalejo, Carolina Gotera, Jesús Javier Sola, Alejandra Roncero, Germán Peces-Barba, Carlos Ruíz-Martínez, José G. Pichel
Publikováno v: Oncogene. 41:3625-3639
Given the long-term ineffectiveness of current therapies and late-stage diagnoses, lung cancer is a leading cause of malignant diseases. Tumor progression is influenced by cancer cell interactions with the tumor microenvironment (TME). Insulin-like g
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5411a0a79b7c9b83837e44f23f45af97
https://doi.org/10.1038/s41388-022-02376-w
Zobrazit plný text záznamu
7
IGF1R deficiency attenuates acute inflammatory response in a bleomycin-induced lung injury mouse model
Autor: Icíar P. López, Lydia Alvarez-Erviti, Sergio Piñeiro-Hermida, María Íñiguez, Raquel Torrens, José G. Pichel, Elvira Alfaro-Arnedo, Carlos Ruíz-Martínez
Publikováno v: Scientific Reports, Vol 7, Iss 1, Pp 1-13 (2017)
Scientific Reports
IGF1R (Insulin-like Growth Factor 1 Receptor) is a tyrosine kinase with pleiotropic cellular functions. IGF activity maintains human lung homeostasis and is implicated in pulmonary diseases such as cancer, ARDS, COPD, asthma and fibrosis. Here we rep
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae790d7ac417051626d31de41d9c3480
https://doaj.org/article/3b2793cee94e4995ba43123296da8895
Zobrazit plný text záznamu
8
Attenuated airway hyperresponsiveness and mucus secretion in HDM-exposed Igf1r-deficient mice
Autor: Icíar P. López, Raquel Torrens, Joshua A. Gregory, José G. Pichel, Carlos Ruíz-Martínez, Sergio Piñeiro-Hermida, Mikael Adner
Publikováno v: Allergy. 72:1317-1326
Background Asthma is a common chronic lung disease characterized by airflow obstruction, airway hyperresponsiveness (AHR) and inflammation. IGFs have been reported to play a role in asthma but little is known about how the Insulin-like Growth Factor
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5960864fb4cdc4e198643f007b9760a4
https://doi.org/10.1111/all.13142
Zobrazit plný text záznamu
10
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.

Vyhledávací nástroje:

Upřesnit hledání

Omezení vyhledávání
Plný text Recenzováno Digitální knihovna AV ČR
Zdroje