Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Carlos Rodríguez-Nogales"'
Autor:
Carlos Rodríguez-Nogales, Joke Meeus, Gaby Thonus, Sam Corveleyn, Eric Allémann, Olivier Jordan
Publikováno v:
Drug Delivery, Vol 30, Iss 1 (2023)
AbstractNano- and micro-technologies can salvage drugs with very low solubility that were doomed to pre-clinical and clinical failure. A unique design approach to develop drug nanocrystals (NCs) loaded in extended release polymeric microparticles (MP
Externí odkaz:
https://doaj.org/article/fe6ab5d8e06947deb553cce8fc7d39e1
Publikováno v:
European Journal of Pharmaceutics and Biopharmaceutics. 172:41-52
Osteoarthritis (OA) is a chronic and inflammatory disease with no effective regenerative treatments to date. The therapeutic potential of mesenchymal stem cells (MSCs) remains to be fully explored. Intra-articular injection of these cells promotes ca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9851a532804bfa6029aeb1987bc221e9
https://doi.org/10.1016/j.ejpb.2022.01.003
https://doi.org/10.1016/j.ejpb.2022.01.003
A unique multidrug nanomedicine made of squalenoyl-gemcitabine and alkyl-lysophospholipid edelfosine
Autor:
Silvia Irusta, Carlos Rodríguez-Nogales, Didier Desmaële, María J. Blanco-Prieto, Victor Sebastian, Patrick Couvreur
Publikováno v:
European Journal of Pharmaceutics and Biopharmaceutics
European Journal of Pharmaceutics and Biopharmaceutics, Elsevier, 2019, 144, pp.165-173. ⟨10.1016/j.ejpb.2019.09.017⟩
European Journal of Pharmaceutics and Biopharmaceutics, Elsevier, 2019, 144, pp.165-173. ⟨10.1016/j.ejpb.2019.09.017⟩
International audience; Among anticancer nanomedicines, squalenoyl nanocomposites have obtained encouraging outcomes in a great variety of tumors. The prodrug squalenoyl-gemcitabine has been chosen in this study to construct a novel multidrug nanosys
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea7baad04098f8cbbab7cb118b03aca0
https://doi.org/10.1016/j.ejpb.2019.09.017
https://doi.org/10.1016/j.ejpb.2019.09.017
Publikováno v:
Journal of Pharmacology and Experimental Therapeutics. 370:625-635
Neuroblastoma (NB) is the most common extracranial solid tumor preferentially occurring in preschoolers. Its characteristic aggressiveness and heterogeneous clinical behavior are especially visible in relapsed or refractory cases and hamper therapeut
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::51bc6aa850c4193a9377eaf89f48f05d
https://doi.org/10.1124/jpet.118.255067
https://doi.org/10.1124/jpet.118.255067
Autor:
Pablo Vicente Torres-Ortega, Laura Saludas, Jon Eneko Idoyaga, Carlos Rodríguez-Nogales, Elisa Garbayo, María José Blanco-Prieto
Publikováno v:
Nanoparticles for Brain Drug Delivery ISBN: 9781003119326
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0415ad42e796997a94fa4464d7d20f3f
https://doi.org/10.1201/9781003119326-8
https://doi.org/10.1201/9781003119326-8
Publikováno v:
Advanced drug delivery reviews. 173
Oral anticancer drugs have earned a seat at the table, as the need for homecare treatment in oncology has increased. Interest in this field is growing as a result of their proven efficacy, lower costs and positive patient uptake. However, the gastroi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d0f4f0319ae3f6f8df6657eb38a518d3
https://pubmed.ncbi.nlm.nih.gov/33774117
https://pubmed.ncbi.nlm.nih.gov/33774117
Autor:
Carlos Rodríguez-Nogales, Patrick Couvreur, Didier Desmaële, Victor Sebastian, María J. Blanco-Prieto
Publikováno v:
ChemMedChem
ChemMedChem, Wiley-VCH Verlag, In press, ⟨10.1002/cmdc.202100464⟩
Dadun. Depósito Académico Digital de la Universidad de Navarra
Consejo Superior de Investigaciones Científicas (CSIC)
Zaguán. Repositorio Digital de la Universidad de Zaragoza
instname
ChemMedChem, Wiley-VCH Verlag, 2020, ⟨10.1002/cmdc.202100464⟩
Digital.CSIC. Repositorio Institucional del CSIC
ChemMedChem, Wiley-VCH Verlag, In press, ⟨10.1002/cmdc.202100464⟩
Dadun. Depósito Académico Digital de la Universidad de Navarra
Consejo Superior de Investigaciones Científicas (CSIC)
Zaguán. Repositorio Digital de la Universidad de Zaragoza
instname
ChemMedChem, Wiley-VCH Verlag, 2020, ⟨10.1002/cmdc.202100464⟩
Digital.CSIC. Repositorio Institucional del CSIC
Therapeutic perspectives of bone tumors such as osteosarcoma remain restricted due to the inefficacy of current treatments. We propose here the construction of a novel anticancer squalene-based nanomedicine with bone affinity and retention capacity.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b2a5c8234e17268d4b0a51e8c1df526
https://hal.archives-ouvertes.fr/hal-03407097
https://hal.archives-ouvertes.fr/hal-03407097
Autor:
Rosa Noguera, Rebeca Burgos-Panadero, Inmaculada Noguera, Samuel Navarro, María J. Blanco-Prieto, Pablo Vicente-Munuera, Carlos Rodríguez-Nogales, Adela Cañete, Souhaila H. El Moukhtari, Susana Martín-Vañó
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
instname
INTERNATIONAL JOURNAL OF PHARMACEUTICS
r-INCLIVA. Repositorio Institucional de Producción Científica de INCLIVA
r-IIS La Fe. Repositorio Institucional de Producción Científica del Instituto de Investigación Sanitaria La Fe
instname
INTERNATIONAL JOURNAL OF PHARMACEUTICS
r-INCLIVA. Repositorio Institucional de Producción Científica de INCLIVA
r-IIS La Fe. Repositorio Institucional de Producción Científica del Instituto de Investigación Sanitaria La Fe
Treatment in children with high-risk neuroblastoma remains largely unsuccessful due to the development of metastases and drug resistance. The biological complexity of these tumors and their microenvironment represent one of the many challenges to fac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3463f7cbbb1f7112549328da95e98f63
http://hdl.handle.net/10261/266085
http://hdl.handle.net/10261/266085
Publikováno v:
Proceedings of The 1st International Electronic Conference on Pharmaceutics.
Introduction: Neuroblastoma is the most frequent pediatric extracranial solid tumor being responsible for 8-10% of all childhood malignancies. Patient outcome is still a major issue due to neuroblastoma’s heterogeneity and complex tumor biology.1,2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::909ec260bb83923ab68d6426e1785926
https://doi.org/10.3390/iecp2020-08800
https://doi.org/10.3390/iecp2020-08800
Autor:
Carolina Zandueta, Patrick Couvreur, Fernando Lecanda, Carlos Rodríguez-Nogales, Didier Desmaële, Haritz Moreno, María J. Blanco-Prieto
Publikováno v:
Cancers
Cancers, MDPI, 2020, 12 (7), pp.1895. ⟨10.3390/cancers12071895⟩
Volume 12
Issue 7
Cancers, Vol 12, Iss 1895, p 1895 (2020)
Cancers, MDPI, 2020, 12 (7), pp.1895. ⟨10.3390/cancers12071895⟩
Volume 12
Issue 7
Cancers, Vol 12, Iss 1895, p 1895 (2020)
Due to chemoresistance and a high propensity to form lung metastasis, survival rates in pediatric osteosarcoma (OS) are poor. With the aim to improve anticancer activity in pediatric OS, a multidrug nanomedicine was designed using the alkyl-lysophosp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::696db3991dc2b7f2db12d8f67c46ab88
https://hal.archives-ouvertes.fr/hal-03371786/document
https://hal.archives-ouvertes.fr/hal-03371786/document