Zobrazeno 1 - 10
of 44
pro vyhledávání: '"Carlos Reguenga"'
Autor:
João Baltar, Rafael Mendes Miranda, Maria Cabral, Sandra Rebelo, Florian Grahammer, Tobias B. Huber, Carlos Reguenga, Filipe Almeida Monteiro
Publikováno v:
Neural Development, Vol 19, Iss 1, Pp 1-16 (2024)
Abstract The cell-adhesion molecule NEPH1 is required for maintaining the structural integrity and function of the glomerulus in the kidneys. In the nervous system of Drosophila and C. elegans, it is involved in synaptogenesis and axon branching, whi
Externí odkaz:
https://doaj.org/article/523764824a2840bab401d48b78bf9204
Autor:
Filipe A. Monteiro, Rafael M. Miranda, Marta C. Samina, Ana F. Dias, Alexandre A. S. F. Raposo, Patrícia Oliveira, Carlos Reguenga, Diogo S. Castro, Deolinda Lima
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
The spinal cord dorsal horn is a major station for integration and relay of somatosensory information and comprises both excitatory and inhibitory neuronal populations. The homeobox gene Tlx3 acts as a selector gene to control the development of late
Externí odkaz:
https://doaj.org/article/52b6f46b404447a7b4f61bba6230db50
Autor:
Ana Rita Costa, Paulina Carvalho, Gunnar Flik, Steven P. Wilson, Carlos Reguenga, Isabel Martins, Isaura Tavares
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 13 (2019)
Opioids play a major role at descending pain modulation but the effects of neuropathic pain on the brain opioidergic system remain understudied. Since descending facilitation is enhanced during neuropathic pain, we studied the opioidergic modulation
Externí odkaz:
https://doaj.org/article/a7678b5a1d594d528fce4cbab7a3bdac
Autor:
Sílvia Sousa Chambel, Ana Ferreira, Raquel Oliveira, Rafael Miranda, Luís Vale, Carlos Reguenga, Martin E. Schwab, Célia Duarte Cruz
Publikováno v:
International Journal of Molecular Sciences; Volume 23; Issue 15; Pages: 8667
Thoracic spinal cord injury (SCI) results in urinary dysfunction, which majorly affects the quality of life of SCI patients. Abnormal sprouting of lumbosacral bladder afferents plays a crucial role in this condition. Underlying mechanisms may include
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb3129fb3dbe72ebf593c500d097d8bb
https://pubmed.ncbi.nlm.nih.gov/35955811
https://pubmed.ncbi.nlm.nih.gov/35955811
Autor:
Armando Teixeira-Pinto, Isaura Tavares, Ana Costa, Marília Sousa, Steven P. Wilson, Isabel Martins, Carlos Reguenga
Publikováno v:
Anesthesiology. 133:628-644
Background Increased descending pain facilitation accounts for opioid-induced hyperalgesia, but the underlying mechanisms remain elusive. Given the role of µ-opioid receptors in opioid-induced hyperalgesia in animals, the authors hypothesized that t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b32054babe887bc19aa6f4b08ee41500
https://doi.org/10.1097/aln.0000000000003412
https://doi.org/10.1097/aln.0000000000003412
Autor:
Catarina Quina-Rodrigues, Blanche Schroen, Diana S. Nascimento, Fabiana Baganha, Tiago L. Laundos, Adelino F. Leite-Moreira, F. J. T. Goncalves, Sara Ribeiro, Francisco Vasques-Nóvoa, Rui J Cerqueira, Wouter Verhesen, Fátima Carneiro, Ricardo Soares-dos-Reis, Stephane Heymans, Roberto Roncon-Albuquerque, José Artur Paiva, Carlos Reguenga, Luís Mendonça, Paulo Castro-Chaves, Perpétua Pinto-do-Ó
Publikováno v:
Critical Care Medicine, 46(9), E945-E954. LIPPINCOTT WILLIAMS & WILKINS
Objectives: Septic shock is a life-threatening clinical situation associated with acute myocardial and vascular dysfunction, whose pathophysiology is still poorly understood. Herein, we investigated microRNA-155-dependent mechanisms of myocardial and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7a35136780598b632d609c2fc0216858
https://doi.org/10.1097/CCM.0000000000003296
https://doi.org/10.1097/CCM.0000000000003296
Autor:
Ana Sofia Pessoa, Ricardo Soares-dos-Reis, Carlos Reguenga, Ana F. Dias, Miguel Falcão, Filipe Monteiro, Mariana Raimundo Matos, Rui Vitorino, Deolinda Lima
Publikováno v:
Biochemical Journal. 474:683-697
Prrxl1 encodes for a paired-like homeodomain transcription factor essential for the correct establishment of the dorsal root ganglion — spinal cord nociceptive circuitry during development. Prrxl1-null mice display gross anatomical disruption of th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7ab28c605c255e0c9f12aaeb367150e8
https://doi.org/10.1042/bcj20160560
https://doi.org/10.1042/bcj20160560
Publikováno v:
European Journal of Neuroscience. 43:1449-1459
The transcription factor Casz1 is required for proper assembly of vertebrate vasculature and heart morphogenesis as well as for temporal control of Drosophila neuroblasts and mouse retina progenitors in the generation of different cell types. Althoug
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::99f40a2779619cd83fceffb6f0f6f657
https://doi.org/10.1111/ejn.13214
https://doi.org/10.1111/ejn.13214
Autor:
Carlos Reguenga, Miguel Falcão, Mariana Raimundo Matos, Deolinda Lima, Filipe Monteiro, Ricardo Soares-dos-Reis, Isabel Regadas
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms. 1839:1121-1131
The proper establishment of the dorsal root ganglion/spinal cord nociceptive circuitry depends on a group of homeodomain transcription factors that includes Prrxl1, Brn3a and Tlx3. By the use of epistatic analysis, it was suggested that Tlx3 and Brn3
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::357e24641b2c6020c817103b0432f304
https://doi.org/10.1016/j.bbagrm.2014.08.007
https://doi.org/10.1016/j.bbagrm.2014.08.007
Publikováno v:
Developmental Dynamics. 239:1684-1694
Perception of noxious events relies on activation of complex central neuronal circuits. The spinal cord dorsal horn plays a pivotal role in the process relaying to the brain various types of somatosensory input. These functions are accomplished by di
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::869c81093cfcd8e880acc769584a8e93
https://doi.org/10.1002/dvdy.22305
https://doi.org/10.1002/dvdy.22305