Zobrazeno 1 - 10
of 49
pro vyhledávání: '"Carlos R. Escalante"'
Publikováno v:
STAR Protocols, Vol 3, Iss 3, Pp 101615- (2022)
Summary: eIF5-mimic protein (5MP) controls translation through its interaction with eukaryotic translation initiation factor (eIF) 2 and eIF3 and alters non-AUG translation rates for oncogenes in cancer and repeat expansions in neurodegenerative dise
Externí odkaz:
https://doaj.org/article/758261de9fe24f2490d42b41fc075812
Autor:
Chingakham Ranjit Singh, M. Rebecca Glineburg, Chelsea Moore, Naoki Tani, Rahul Jaiswal, Ye Zou, Eric Aube, Sarah Gillaspie, Mackenzie Thornton, Ariana Cecil, Madelyn Hilgers, Azuma Takasu, Izumi Asano, Masayo Asano, Carlos R. Escalante, Akira Nakamura, Peter K. Todd, Katsura Asano
Publikováno v:
Cell Reports, Vol 36, Iss 2, Pp 109376- (2021)
Summary: eIF5-mimic protein (5MP) is a translational regulatory protein that binds the small ribosomal subunit and modulates its activity. 5MP is proposed to reprogram non-AUG translation rates for oncogenes in cancer, but its role in controlling non
Externí odkaz:
https://doaj.org/article/5cad839a14af4e99972d37594a69c639
Autor:
Leticia Agúndez, Francisco Zárate-Pérez, Anita F Meier, Martino Bardelli, Matxalen Llosa, Carlos R Escalante, R Michael Linden, Els Henckaerts
Publikováno v:
PLoS ONE, Vol 13, Iss 7, p e0200841 (2018)
Endonucleases of the HUH family are specialized in processing single-stranded DNA in a variety of evolutionarily highly conserved biological processes related to mobile genetic elements. They share a structurally defined catalytic domain for site-spe
Externí odkaz:
https://doaj.org/article/98c52808bd7640ee9cae96280b3cae75
Autor:
Kamyar Sharifi, Vishaka Santosh, Francisco Zarate-Perez, Els Henckaerts, Kelly A. Dryden, Carlos R. Escalante, Molly Endicott, Rahul Jaiswal, Bram Vandewinkel, Caroline Dierckx, Faik N. Musayev
Publikováno v:
Nucleic Acids Research
The adeno-associated virus (AAV) non-structural Rep proteins catalyze all the DNA transactions required for virus viability including, DNA replication, transcription regulation, genome packaging, and during the latent phase, site-specific integration
Autor:
Chelsea Moore, Madelyn Hilgers, Ariana Cecil, Naoki Tani, Akira Nakamura, Katsura Asano, Ye Zou, Rahul Jaiswal, Peter K. Todd, Chingakham Ranjit Singh, Masayo Asano, Sarah Gillaspie, Eric Aube, Izumi Asano, Mackenzie M. Thornton, Azuma Takasu, M. Rebecca Glineburg, Carlos R. Escalante
Publikováno v:
Cell Reports, Vol 36, Iss 2, Pp 109376-(2021)
Cell Rep
Cell Rep
Summary: eIF5-mimic protein (5MP) is a translational regulatory protein that binds the small ribosomal subunit and modulates its activity. 5MP is proposed to reprogram non-AUG translation rates for oncogenes in cancer, but its role in controlling non
Autor:
J.N. Scarsdale, Faik N. Musayev, John W. Burgner, Carlos R. Escalante, Janina P. Lewis, B.R. Belvin
Publikováno v:
Acta Crystallographica Section D Structural Biology. 75:437-450
Although the HcpR regulator plays a vital step in initiation of the nitrosative stress response in many Gram-negative anaerobic bacteria, the molecular mechanisms that it uses to mediate gas sensing are not well understood. Here, a 2.6 Å resolution
Autor:
Kamyar Sharifi, Kelly A. Dryden, Vishaka Santosh, Molly Endicott, Els Henckaerts, Rahul Jaiswal, Faik N. Musayev, Francisco Zarate-Perez, Carlos R. Escalante, Caroline Dierckx, Bram Vandewinkel
The adeno-associated virus (AAV) Rep proteins use a unique AAA+domain to catalyze DNA replication, transcription regulation, and genome packaging. Also, they mediate site-specific integration during a latent phase. To understand the mechanisms underl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0a346a498243083072d146b0d8c57396
https://doi.org/10.1101/2020.06.02.126235
https://doi.org/10.1101/2020.06.02.126235
Autor:
Francisco Zarate-Perez, Martino Bardelli, John W Burgner, Maria Villamil-Jarauta, Kanni Das, Demet Kekilli, Jorge Mansilla-Soto, R Michael Linden, Carlos R Escalante
Publikováno v:
PLoS Pathogens, Vol 8, Iss 6, p e1002764 (2012)
The four Rep proteins of adeno-associated virus (AAV) orchestrate all aspects of its viral life cycle, including transcription regulation, DNA replication, virus assembly, and site-specific integration of the viral genome into the human chromosome 19
Externí odkaz:
https://doaj.org/article/8383382c475e49a99b405c2aa629f43c
Autor:
Jorge Mansilla-Soto, Miran Yoon-Robarts, William J Rice, Shailee Arya, Carlos R Escalante, R Michael Linden
Publikováno v:
PLoS Pathogens, Vol 5, Iss 7, p e1000513 (2009)
Rep68 is a multifunctional protein of the adeno-associated virus (AAV), a parvovirus that is mostly known for its promise as a gene therapy vector. In addition to its role as initiator in viral DNA replication, Rep68 is essential for site-specific in
Externí odkaz:
https://doaj.org/article/113c6e3818ce4a148e9456a05bcb1f14
Publikováno v:
Journal of Biological Chemistry. 290:27779-27790
IRF4 is a unique member of the interferon regulatory factor (IRF) family playing critical regulatory roles in immune cell development, regulation of obesity-induced inflammation, and control of thermogenic gene expression. The ability of IRF4 to cont