Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Carlos R, Dostal"'
Autor:
Carlos R. Dostal, Megan Carson Sulzer, Keith W. Kelley, Gregory G. Freund, Robert H. McCusker
Publikováno v:
Neurobiology of Stress, Vol 7, Iss , Pp 1-15 (2017)
Stressors activate the hypothalamic-pituitary-adrenal (HPA) axis and immune system eliciting changes in cognitive function, mood and anxiety. An important link between stress and altered behavior is stimulation of the Kynurenine Pathway which generat
Externí odkaz:
https://doaj.org/article/e46528d418ea482496eb60bfbe2cfb20
Publikováno v:
Brain, Behavior, and Immunity. 69:321-335
Behavioral symptoms associated with mood disorders have been intimately linked with immunological and psychological stress. Induction of immune and stress pathways is accompanied by increased tryptophan entry into the Kynurenine (Kyn) Pathway as gove
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1cbba97027614ad980fbefba47c74f8b
https://doi.org/10.1016/j.bbi.2017.12.006
https://doi.org/10.1016/j.bbi.2017.12.006
Autor:
Keith W. Kelley, Gregory G. Freund, Megan Carson Sulzer, Carlos R. Dostal, Robert H. McCusker
Publikováno v:
Neurobiology of Stress, Vol 7, Iss, Pp 1-15 (2017)
Stressors activate the hypothalamic-pituitary-adrenal (HPA) axis and immune system eliciting changes in cognitive function, mood and anxiety. An important link between stress and altered behavior is stimulation of the Kynurenine Pathway which generat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::93f3e7d08664e02d6bac408bffe0b9eb
http://www.sciencedirect.com/science/article/pii/S2352289516300492
http://www.sciencedirect.com/science/article/pii/S2352289516300492
Autor:
Kathleen Swoap, Lijie Zhai, David C. Binder, Galina Gritsina, Derek A. Wainwright, Erik Ladomersky, Kristen L. Lauing, Meijing Wu, Leah K. Billingham, Robert H. McCusker, Carlos R. Dostal
Publikováno v:
Brain, Behavior, and Immunity. 62:24-29
Glioblastoma (GBM) is the most common malignant brain tumor in adults with a median survival of 14.6 months. A contributing factor to GBM aggressiveness is the intratumoral expression of the potently immunosuppressive enzyme, indoleamine 2,3 dioxygen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::182ce30a2e5323d71ee8969deb3993ff
https://doi.org/10.1016/j.bbi.2017.01.022
https://doi.org/10.1016/j.bbi.2017.01.022
Autor:
Galina Gritsina, Alfred Rademaker, Rimas V. Lukas, Andrew T. Parsa, Lijie Zhai, Derek A. Wainwright, Orin Bloch, Robert H. McCusker, Carlos R. Dostal, Mahua Dey, Kristen L. Lauing, Rajwant Kaur, Jeffrey Raizer, M. Kelly Nicholas
Publikováno v:
Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia, vol 22, iss 12
We hypothesized that peripheral tryptophan (Trp) and/or kynurenine (Kyn) levels would provide prognostic value for physicians planning to enroll glioblastoma multiforme (GBM) patients in immunotherapy. GBM is the most common form of malignant glioma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f73ae06bd5882a4c9b2d067e54364e52
https://doi.org/10.1016/j.jocn.2015.06.018
https://doi.org/10.1016/j.jocn.2015.06.018
Autor:
Carlos R, Dostal, Megan, Carson Sulzer, Keith W, Kelley, Gregory G, Freund, Robert H, McCusker
Publikováno v:
Neurobiology of Stress
Stressors activate the hypothalamic-pituitary-adrenal (HPA) axis and immune system eliciting changes in cognitive function, mood and anxiety. An important link between stress and altered behavior is stimulation of the Kynurenine Pathway which generat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::6a265514a8e445e798b30ef8e0ea88cf
https://pubmed.ncbi.nlm.nih.gov/29520368
https://pubmed.ncbi.nlm.nih.gov/29520368
Autor:
Galina Gritsina, Lijie Zhai, Derek A. Wainwright, Jun Qian, Robert H. McCusker, Carlos R. Dostal, Kristen L. Lauing
The upregulation of indoleamine 2,3 dioxygenase 1 (IDO1) in glioblastoma (GBM) is associated with significantly decreased survival in patients. We have previously demonstrated that glioma-derived IDO1 is required for Treg accumulation and immune-evas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::261ca0b492814e09de728f058febb2ef
https://europepmc.org/articles/PMC4638894/
https://europepmc.org/articles/PMC4638894/
Publikováno v:
Brain, Behavior, and Immunity. 57:e37
Stress alters behavior and increases expression of rate-limiting tryptophan/indoleamine-2,3-dioxygenases (DO’s: Tdo2, Ido1, Ido2) within the Kynurenine Pathway. Increased kynurenine is implicated as a causal agent mediating stress-induced behaviors
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0ad1b0d7a219357fed11c38b8b996235
https://doi.org/10.1016/j.bbi.2016.07.124
https://doi.org/10.1016/j.bbi.2016.07.124