Zobrazeno 1 - 10
of 53
pro vyhledávání: '"Carlos Pintado"'
Autor:
Javier Garcia-Pardo, Aleksandra E. Badaczewska-Dawid, Carlos Pintado-Grima, Valentín Iglesias, Aleksander Kuriata, Sebastian Kmiecik, Salvador Ventura
Publikováno v:
Microbial Cell Factories, Vol 22, Iss 1, Pp 1-10 (2023)
Abstract Background The budding yeast Saccharomyces cerevisiae (S. cerevisiae) is a well-established model system for studying protein aggregation due to the conservation of essential cellular structures and pathways found across eukaryotes. However,
Externí odkaz:
https://doaj.org/article/85f3760bcf784292a615fc060c301274
Autor:
Carlos Pintado-Grima, Oriol Bárcenas, Andrea Bartolomé-Nafría, Marc Fornt-Suñé, Valentín Iglesias, Javier Garcia-Pardo, Salvador Ventura
Publikováno v:
Biophysica, Vol 3, Iss 1, Pp 1-20 (2023)
The presence of insoluble protein deposits in tissues and organs is a hallmark of many human pathologies. In addition, the formation of protein aggregates is considered one of the main bottlenecks to producing protein-based therapeutics. Thus, there
Externí odkaz:
https://doaj.org/article/1f94c3e420fa44458982adf40c6c7cd0
Autor:
Oriol Bárcenas, Carlos Pintado-Grima, Katarzyna Sidorczuk, Felix Teufel, Henrik Nielsen, Salvador Ventura, Michał Burdukiewicz
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 20, Iss , Pp 6526-6533 (2022)
Peptides are known to possess a plethora of beneficial properties and activities: antimicrobial, anticancer, anti-inflammatory or the ability to cross the blood–brain barrier are only a few examples of their functional diversity. For this reason, b
Externí odkaz:
https://doaj.org/article/059d0bdbc9b1445499128796c2ffab14
Autor:
Carlos Pintado-Grima, Jaime Santos, Valentín Iglesias, Zoe Manglano-Artuñedo, Irantzu Pallarès, Salvador Ventura
Publikováno v:
Frontiers in Plant Science, Vol 13 (2023)
Prion-like domains (PrLDs) are intrinsically disordered regions (IDRs) of low sequence complexity with a similar composition to yeast prion domains. PrLDs-containing proteins have been involved in different organisms’ regulatory processes. Regions
Externí odkaz:
https://doaj.org/article/15657a46eaa94e05bef086f68174c190
Autor:
Carlos Pintado-Grima, Oriol Bárcenas, Zoe Manglano-Artuñedo, Rita Vilaça, Sandra Macedo-Ribeiro, Irantzu Pallarès, Jaime Santos, Salvador Ventura
Publikováno v:
Frontiers in Molecular Biosciences, Vol 9 (2022)
Proteome-wide analyses suggest that most globular proteins contain at least one amyloidogenic region, whereas these aggregation-prone segments are thought to be underrepresented in intrinsically disordered proteins (IDPs). In recent work, we reported
Externí odkaz:
https://doaj.org/article/482528cf6fe44e2db903fe137ee4afc7
Publikováno v:
Frontiers in Molecular Biosciences, Vol 8 (2021)
Proteins bearing prion-like domains (PrLDs) are essential players in stress granules (SG) assembly. Analysis of data on heat stress-induced recruitment of yeast PrLDs to SG suggests that this propensity might be connected with three defined protein b
Externí odkaz:
https://doaj.org/article/22e9497396824d20990dea0b9776c28d
Publikováno v:
Biomolecules, Vol 12, Iss 7, p 974 (2022)
Intrinsically disordered proteins (IDPs) are essential players in the assembly of biomolecular condensates during liquid–liquid phase separation (LLPS). Disordered regions (IDRs) are significantly exposed to the solvent and, therefore, highly influ
Externí odkaz:
https://doaj.org/article/88ae7e0d42044155b1070917ca621dea
Publikováno v:
Biomolecules, Vol 11, Iss 11, p 1596 (2021)
Proteins are exposed to fluctuating environmental conditions in their cellular context and during their biotechnological production. Disordered regions are susceptible to these fluctuations and may experience solvent-dependent conformational switches
Externí odkaz:
https://doaj.org/article/a721b402a68b43ca97d907efc1919c9f
Publikováno v:
Gazeta Médica, Vol 6, Iss 3 (2019)
A rutura bilateral do tendão quadricipital é uma lesão rara, não sendo muitas vezes diagnosticada na apresentação inicial. Apresenta-se o caso de um doente de 41 anos, género masculino, sem antecedentes médico-cirúrgicos ou medicação habit
Externí odkaz:
https://doaj.org/article/137e856aad7b4be68c72ddfa9355e2f6
Autor:
Carlos Pintado, George B. Henson
Publikováno v:
World Literature Today. 95:62-65
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d5f59bd612a6840d38fe1127e1497134
https://doi.org/10.1353/wlt.2021.0272
https://doi.org/10.1353/wlt.2021.0272