Brucella NpeA is a secreted Type IV effector containing an N-WASP-binding short linear motif that promotes niche formation

Autor: Agostina Giménez, Mariela G. Del Giudice, Paula V. López, Francisco Guaimas, Hugo Sámano-Sánchez, Toby J. Gibson, Lucía B. Chemes, Carlos O. Arregui, Juan E. Ugalde, Cecilia Czibener

Publikováno v: mBio, Vol 15, Iss 7 (2024)

ABSTRACT The modulation of actin polymerization is a common theme among microbial pathogens. Even though microorganisms show a wide repertoire of strategies to subvert the activity of actin, most of them converge in the ones that activate nucleating

Externí odkaz: https://doaj.org/article/c5673d10faf044ff926512acf31c6281

P120-Catenin Regulates Early Trafficking Stages of the N-Cadherin Precursor Complex.

Autor: Diana P Wehrendt, Fernando Carmona, Ana E González Wusener, Ángela González, Juan M Lázaro Martínez, Carlos O Arregui

Publikováno v: PLoS ONE, Vol 11, Iss 6, p e0156758 (2016)

It is well established that binding of p120 catenin to the cytoplasmic domain of surface cadherin prevents cadherin endocytosis and degradation, contributing to cell-cell adhesion. In the present work we show that p120 catenin bound to the N-cadherin

Externí odkaz: https://doaj.org/article/092e874160b342cebd70ff13b6247cc0

Protein tyrosine phosphatase 1B targets focal adhesion kinase and paxillin in cell-matrix adhesions

Autor: María E Perez Collado, Ignacio J. General, Ana E. González Wusener, Angela González, Melina R Maza, Carlos O. Arregui

Publikováno v: Journal of cell science. 134(20)

Protein tyrosine phosphatase 1B (PTP1B, also known as PTPN1) is an established regulator of cell-matrix adhesion and motility. However, the nature of substrate targets at adhesion sites remains to be validated. Here, we used bimolecular fluorescence

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::71622c6f513b8f3c761b18ddccb5d12c
https://pubmed.ncbi.nlm.nih.gov/34553765

ER-bound protein tyrosine phosphatase PTP1B interacts with Src at the plasma membrane/substrate interface.

Autor: Melisa C Monteleone, Ana E González Wusener, Juan E Burdisso, Cecilia Conde, Alfredo Cáceres, Carlos O Arregui

Publikováno v: PLoS ONE, Vol 7, Iss 6, p e38948 (2012)

PTP1B is an endoplasmic reticulum (ER) anchored enzyme whose access to substrates is partly dependent on the ER distribution and dynamics. One of these substrates, the protein tyrosine kinase Src, has been found in the cytosol, endosomes, and plasma

Externí odkaz: https://doaj.org/article/93dc02ab51d046c7ae1806ebe3af3001

P120-Catenin Regulates Early Trafficking Stages of the N-Cadherin Precursor Complex

Autor: Juan Manuel Lázaro Martínez, Ana E. González Wusener, Carlos O. Arregui, Angela González, Fernando Carmona, Diana Patricia Wehrendt

Publikováno v: CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
PLoS ONE, Vol 11, Iss 6, p e0156758 (2016)
PLoS ONE

It is well established that binding of p120 catenin to the cytoplasmic domain of surface cadherin prevents cadherin endocytosis and degradation, contributing to cell-cell adhesion. In the present work we show that p120 catenin bound to the N-cadherin

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b9427886654ea83307cdfc50384d406
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0156758