Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Carlos N Martinez"'
Autor:
Tomas Kirchhoff, Iman Osman, Michelle Krogsgaard, Russell S. Berman, Richard L. Shapiro, Esther Kazlow, Artur Romanchuk, Karolina Malecek, Anuj Bapodra, Justin Rendleman, Carlos N. Martinez, Matjaz Vogelsang
Supplementary Tables 1-4, Supplementary Figures 1-3 - Supplementary Table 1. List of Immunomodulatory genes selected for the study;Supplementary Table 2. Top 50 SNP-probe pairs selected for genotyping; Supplementary Table 3. Multivariate Cox model fo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e088f4d503430027b46aec0b19c9d9a
https://doi.org/10.1158/1078-0432.22456688
https://doi.org/10.1158/1078-0432.22456688
Autor:
Tomas Kirchhoff, Iman Osman, Michelle Krogsgaard, Russell S. Berman, Richard L. Shapiro, Esther Kazlow, Artur Romanchuk, Karolina Malecek, Anuj Bapodra, Justin Rendleman, Carlos N. Martinez, Matjaz Vogelsang
Purpose: The identification of personalized germline markers with biologic relevance for the prediction of cutaneous melanoma prognosis is highly demanded but to date, it has been largely unsuccessful. As melanoma progression is controlled by host im
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0390c162431e9257418777ff27436402
https://doi.org/10.1158/1078-0432.c.6523388.v1
https://doi.org/10.1158/1078-0432.c.6523388.v1
Autor:
Robert Ferguson, Kelsey Monson, Leah Morales, John Cadley, Carlos N Martinez, Vylyny Chat, Danny Simpson, Jeffrey S. Weber, Iman Osman, Tomas Kirchhoff, Eduardo Esteva
Publikováno v:
Journal of Translational Medicine
Journal of Translational Medicine, Vol 19, Iss 1, Pp 1-11 (2021)
Journal of Translational Medicine, Vol 19, Iss 1, Pp 1-11 (2021)
Background Tumor mutation burden (TMB) has been associated with melanoma immunotherapy (IT) outcomes, including survival. We explored whether combining TMB with immunogenomic signatures recently identified by The Cancer Genome Atlas (TCGA) can refine
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cec953995190b9b095441b955264b8b7
http://europepmc.org/articles/PMC7888085
http://europepmc.org/articles/PMC7888085
Autor:
Eleazar Vega-Saenz de Miera, Elena Castellano-Sanz, Carlos N Martinez, Tomas Kirchhoff, Iman Osman, Una Moran, Eva Hernando, Alfredo Floristán, Igor Dolgalev, Alejandro Ulloa-Morales, Leah Morales, Douglas Hanniford, Farbod Darvishian
Publikováno v:
Pigment Cell Melanoma Res
Next-generation sequencing has enabled genetic and genomic characterization of melanoma to an unprecedent depth. However, the high mutational background plus the limited depth of coverage of whole-genome sequencing performed on cutaneous melanoma sam
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f1235c0c6328c6a6d596543a6555579
https://europepmc.org/articles/PMC7180098/
https://europepmc.org/articles/PMC7180098/
Autor:
Richard L. Shapiro, Karolina Malecek, Tomas Kirchhoff, Iman Osman, Russell S. Berman, Anuj Bapodra, Justin Rendleman, Michelle Krogsgaard, Carlos N Martinez, Esther Kazlow, Artur Romanchuk, Matjaz Vogelsang
Publikováno v:
Clinical Cancer Research. 22:3268-3280
Purpose: The identification of personalized germline markers with biologic relevance for the prediction of cutaneous melanoma prognosis is highly demanded but to date, it has been largely unsuccessful. As melanoma progression is controlled by host im
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de0c2fb41ac705064202488d3f02d87f
https://doi.org/10.1158/1078-0432.ccr-15-2066
https://doi.org/10.1158/1078-0432.ccr-15-2066
Autor:
J. Cadley, Eduardo Esteva, L. Morales, Carlos N Martinez, Danny Simpson, Tomas Kirchhoff, Jeffrey S. Weber, V. Chat, Iman Osman, Robert Ferguson
Publikováno v:
Annals of Oncology. 30:v556
Background Tumor-specific indicators, such as tumor mutation burden (TMB) have been shown to affect overall survival (OS) in melanoma. Recently, pan-cancer analyses from The Cancer Genome Atlas (TCGA) discovered specific tumor immune signatures predi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7da9859555479e4e67f00d2cb27b30c7
https://doi.org/10.1093/annonc/mdz255.052
https://doi.org/10.1093/annonc/mdz255.052
Autor:
Matjaz Vogelsang, Justin Rendleman, Khagay Nagdimov, Karan Rai, Mohamed H. Abdel-Rahman, Tomas Kirchhoff, Esther Kazlow, Iman Osman, Robert Ferguson, Frederick H. Davidorf, Robert Pilarski, Esma Ucisik-Akkaya, Carlos N Martinez, Robert J. Klein, Colleen M. Cebulla
Publikováno v:
Scientific Reports
While the role of genetic risk factors in the etiology of uveal melanoma (UM) has been strongly suggested, the genetic susceptibility to UM is currently vastly unexplored. Due to shared epidemiological risk factors between cutaneous melanoma (CM) and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1bb0fa1c04e13a96b1480eba36d0317b
https://doi.org/10.1038/srep31191
https://doi.org/10.1038/srep31191
Autor:
Matjaz Vogelsang, Danny Simpson, Tomas Kirchhoff, Iman Osman, Anna C. Pavlick, Jeffrey S. Weber, Esther Kazlow, Robert Ferguson, Melissa Wilson, Carlos N Martinez
Publikováno v:
Annals of Oncology. 28:v407-v408
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0b3ec9889bc88cad765313459e845906
https://doi.org/10.1093/annonc/mdx376.012
https://doi.org/10.1093/annonc/mdx376.012
Genetic associations of the interleukin locus at 1q32.1 with clinical outcomes of cutaneous melanoma
Autor:
Anuj Bapodra, Christina Adaniel, Tomas Kirchhoff, Jerry Shields, Russell S. Berman, Justin Rendleman, Anna C. Pavlick, Carlos N Martinez, David Polsky, Richard L. Shapiro, Matjaz Vogelsang, Nathaniel H. Fleming, Iman Osman, Yongzhao Shao, Ines Pires da Silva, Duane Moogk, Michelle Krogsgaard
Background Due to high melanoma immunogenicity, germline genetic variants in immune pathways have been studied for association with melanoma prognosis. However, limited candidate selection, inadequate power, or lack of independent validation have ham
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f4085e140f022da766b8f46a9723d38
https://europepmc.org/articles/PMC5166523/
https://europepmc.org/articles/PMC5166523/
Autor:
Jeffrey S. Weber, Esther Kazlow, Robert Ferguson, Anna C. Pavlick, Iman Osman, Carlos N Martinez, Antoni Ribas, Tomas Kirchhoff, Ryan J. Sullivan, Keith T. Flaherty, Una Moran, Matjaz Vogelsang, Danny Simpson
Publikováno v:
Journal of Clinical Oncology. 35:3017-3017
3017 Background: Approximately 40-60% of metastatic cutaneous melanoma (CM) patients do not respond to the current immunotherapy (IT) regimens, pointing to other yet unknown factors conferring IT resistance. Based on our recent findings showing that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2a1f07778aff1240c148a15086b49dcf
https://doi.org/10.1200/jco.2017.35.15_suppl.3017
https://doi.org/10.1200/jco.2017.35.15_suppl.3017