Zobrazeno 1 - 10
of 39
pro vyhledávání: '"Carlos Moran Segura"'
Autor:
Filip Ionescu, Jonathan Nguyen, Carlos Moran Segura, Mahati Paravathaneni, G. Daniel Grass, Peter Johnstone, Niki M. Zacharias, Curtis A. Pettaway, Xin Lu, Youngchul Kim, Junmin Whiting, Jasreman Dhillon, Steven A. Eschrich, Juskaran Chadha, Keerthi Gullapalli, Gabriel Roman Souza, Hiroko Miyagi, Brandon J. Manley, Philippe E. Spiess, Jad Chahoud
Publikováno v:
Cancers, Vol 16, Iss 2, p 303 (2024)
Penile squamous cell carcinoma (PSCC) is a rare and deadly malignancy. Therapeutic advances have been stifled by a poor understanding of disease biology. Specifically, the immune microenvironment is an underexplored component in PSCC and the activity
Externí odkaz:
https://doaj.org/article/c2105701a6cd41deb39831165b864a65
Autor:
ThuLe Trinh, William A. Adams, Alexandra Calescibetta, Nhan Tu, Robert Dalton, Tina So, Max Wei, Grace Ward, Elena Kostenko, Sean Christiansen, Ling Cen, Amy McLemore, Kayla Reed, Junmin Whitting, Danielle Gilvary, Neale Lopez Blanco, Carlos Moran Segura, Jonathan Nguyen, Wendy Kandell, Xianghong Chen, Pingyan Cheng, Gabriela M. Wright, W. Douglas Cress, Jinghong Liu, Kenneth L. Wright, Sheng Wei, Erika A. Eksioglu
Publikováno v:
iScience, Vol 26, Iss 4, Pp 106443- (2023)
Summary: Advances in the understanding of the tumor microenvironment have led to development of immunotherapeutic strategies, such as chimeric antigen receptor T cells (CAR-Ts). However, despite success in blood malignancies, CAR-T therapies in solid
Externí odkaz:
https://doaj.org/article/09130f12d9894f7784d26defbf9b2e06
Autor:
Christopher Wilson, Alex C Soupir, Ram Thapa, Jordan Creed, Jonathan Nguyen, Carlos Moran Segura, Travis Gerke, Joellen M Schildkraut, Lauren C Peres, Brooke L Fridley
Publikováno v:
PLoS Computational Biology, Vol 18, Iss 3, p e1009900 (2022)
New technologies, such as multiplex immunofluorescence microscopy (mIF), are being developed and used for the assessment and visualization of the tumor immune microenvironment (TIME). These assays produce not only an estimate of the abundance of immu
Externí odkaz:
https://doaj.org/article/6ba969439c0d438da30057073f808522
Autor:
Christopher M. Wilson, Oscar E. Ospina, Mary K. Townsend, Jonathan Nguyen, Carlos Moran Segura, Joellen M. Schildkraut, Shelley S. Tworoger, Lauren C. Peres, Brooke L. Fridley
Publikováno v:
Cancers, Vol 13, Iss 12, p 3031 (2021)
Immune modulation is considered a hallmark of cancer initiation and progression. The recent development of immunotherapies has ushered in a new era of cancer treatment. These therapeutics have led to revolutionary breakthroughs; however, the efficacy
Externí odkaz:
https://doaj.org/article/ad41a991734f4409aa325e9d6e35ebec
Autor:
Cassandra A. Hathaway, Jose R. Conejo-Garcia, Brooke L. Fridley, Bernard Rosner, Daryoush Saeed-Vafa, Carlos Moran Segura, Jonathan V. Nguyen, Jonathan L. Hecht, Naoko Sasamoto, Kathryn L. Terry, Shelley S. Tworoger, Mary K. Townsend
Publikováno v:
Cancer Epidemiology, Biomarkers & Prevention. 32:848-853
Background: Despite the immunogenic nature of many ovarian tumors, treatment with immune checkpoint therapies has not led to substantial improvements in ovarian cancer survival. To advance population-level research on the ovarian tumor immune microen
Autor:
Cassandra A. Hathaway, Tianyi Wang, Mary K. Townsend, Christine Vinci, Danielle E. Jake-Schoffman, Daryoush Saeed-Vafa, Carlos Moran Segura, Jonathan V. Nguyen, Jose R. Conejo-Garcia, Brooke L. Fridley, Shelley S. Tworoger
Publikováno v:
Cancer Epidemiology, Biomarkers & Prevention. 32:66-73
Background: Exposure to cigarette smoke, particularly in early life, is modestly associated with ovarian cancer risk and may impact systemic immunity and the tumor immune response. However, no studies have evaluated whether cigarette smoke exposure i
Autor:
Mary K. Townsend, Shelley S. Tworoger, Kathryn L. Terry, Naoko Sasamoto, Jonathan L. Hecht, Jonathan V. Nguyen, Carlos Moran Segura, Daryoush Saeed-Vafa, Bernard Rosner, Brooke L. Fridley, Jose R. Conejo-Garcia, Cassandra A. Hathaway
Supplemental Table 1 shows the correlations of percentages of the markers in the tumor.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::799bbb155c590620add1200809abdebc
https://doi.org/10.1158/1055-9965.22593370
https://doi.org/10.1158/1055-9965.22593370
Autor:
Mary K. Townsend, Shelley S. Tworoger, Kathryn L. Terry, Naoko Sasamoto, Jonathan L. Hecht, Jonathan V. Nguyen, Carlos Moran Segura, Daryoush Saeed-Vafa, Bernard Rosner, Brooke L. Fridley, Jose R. Conejo-Garcia, Cassandra A. Hathaway
Supplemental Figure 1 provides representative images from the T cell panel for high-grade serous, endometrioid, clear cell, and mucinous tumors.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::910ab62f439760eb3afcc2c9a9cde64a
https://doi.org/10.1158/1055-9965.22593376
https://doi.org/10.1158/1055-9965.22593376
Autor:
Mary K. Townsend, Shelley S. Tworoger, Kathryn L. Terry, Naoko Sasamoto, Jonathan L. Hecht, Jonathan V. Nguyen, Carlos Moran Segura, Daryoush Saeed-Vafa, Bernard Rosner, Brooke L. Fridley, Jose R. Conejo-Garcia, Cassandra A. Hathaway
Supplemental Figure 2 provides representative images from the immune checkpoint panel for high-grade serous, endometrioid, clear cell, and mucinous tumors.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1bcc91d4411ed7b8fa6b08ca5cc783ea
https://doi.org/10.1158/1055-9965.22593373
https://doi.org/10.1158/1055-9965.22593373
Autor:
Mary K. Townsend, Shelley S. Tworoger, Kathryn L. Terry, Naoko Sasamoto, Jonathan L. Hecht, Jonathan V. Nguyen, Carlos Moran Segura, Daryoush Saeed-Vafa, Bernard Rosner, Brooke L. Fridley, Jose R. Conejo-Garcia, Cassandra A. Hathaway
Supplemental Table 2 shows the distribution of presence/absence of percentage of the marker in the tumor, by age of sample for type I and type II tumors
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c25fb5157f1d53950f8f80cdda828fc
https://doi.org/10.1158/1055-9965.22593367.v1
https://doi.org/10.1158/1055-9965.22593367.v1