Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Carlos Mayato"'
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
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A series of alkyl β-d-glucopyranosyl-(1→6)-β-d-glucopyranosides, containing nonchiral and chiral aglycons, were synthesized and analyzed by NMR and CD. The results, collected from four sets of disaccharides, demonstrated that the rotational prope
Publikováno v:
Tetrahedron: Asymmetry. 18:2803-2811
A series of alkyl α- d - C -glucopyranosides were synthesized and their conformational properties analyzed by CD and NMR spectroscopy. The conformational analysis revealed that the hydroxymethyl group populations (torsion angle ω , O1–C1–C2–O
Autor:
Rubén P. Machı´n, Carlos Mayato, Jesús T. Vázquez, José M. Padrón, Carlos A. Sanhueza, Rosa L. Dorta
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 17:3676-3681
Fifty-two C-glycosides were synthesized and their in-vitro antiproliferative activity screened against human cervical carcinoma (HeLa) and osteosarcoma (HOS) cell lines. Nine of them had growth inhibitions (GI(50) values) below 10 microM, the C-gluco
Publikováno v:
Tetrahedron Letters. 49:1396-1398
The glycosyl amino acids α-GalNAc-Ser and α-GalNAc-Thr are fundamental building blocks for glycopeptide synthesis, Schmidt’s synthesis method often being chosen for this purpose. Methyl esters used as orthogonal carboxylic acid protecting group i
Autor:
Sara Tejera, Francisco Estévez, Carlos Mayato, Sara Estévez, María Teresa Marrero, José Quintana, Jesús T. Vázquez, Rosa L. Dorta
Publikováno v:
Bioorganicmedicinal chemistry letters. 22(11)
A series of alkyl α/β-(1→6)-diglucopyranosides 1−12 were synthesized and assessed for cytotoxicity against HL-60, U937, Molt-3 and MCF-7 cancer cell lines. The menthyl derivatives displayed strong cytotoxic properties showing IC 50 values betwe
Publikováno v:
Carbohydrate research. 352
A series of carbasugars were prepared and their conformational properties studied by means of NMR spectroscopy. The results were compared to those previously found for O-, S-, and C-β-glycoside analogs. While the rotational populations of the hydrox
Autor:
Rosa L. Dorta, Jesús T. Vázquez, Luis P. Calle, Jesús Jiménez-Barbero, Filipa Marcelo, Gemma Arsequell, Veronica Gonzalez-Nunez, Katherine Barreto-Valer, Gregorio Valencia, Carlos Mayato, Raquel E. Rodríguez, Mònica Rosa
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
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10 páginas, 6 figuras, 1 tabla -- PAGS nros. 6133-6142
To examine if the biological activity of the N/OFQ peptide, which is the native ligand of the pain-related and viable drug target NOP receptor, could be modulated by glycosylation and if su
To examine if the biological activity of the N/OFQ peptide, which is the native ligand of the pain-related and viable drug target NOP receptor, could be modulated by glycosylation and if su
Autor:
Rosa L. Dorta, Raquel E. Rodríguez, Jesus Trujillo-Vazquez, Mònica Rosa, Gregorio Valencia, Jesús Jiménez-Barbero, Filipa Marcelo, Carlos Mayato, Luis P. Calle, Veronica Gonzalez-Nunez, Gemma Arsequell, Katerine Barreto-Valer, Maria Morando
Publikováno v:
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Publikováno v:
ChemInform. 39
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
instname
instname
A series of alkyl β-d-glucopyranosyl-(1→6)-α-d-glucopyranosides were synthesized and analyzed by NMR and CD techniques. As in their β-anomer series, the rotational populations of the hydroxymethyl group involved in the interglycosidic linkage (t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dfd3b295defbcfa818832a375f032651
http://hdl.handle.net/10261/212225
http://hdl.handle.net/10261/212225