Romosozumab Enhances Vertebral Bone Structure in Women With Low Bone Density

Autor: Carlos Mautalen, Y.-C. Yang, K Poole, Christopher Recknor, Andreas Grauer, M. A. Bolognese, Graham M. Treece, David A. Hanley, RA Pearson, Tristan Whitmarsh, Andrew H. Gee, Jacques P. Brown, Cesar Libanati, Stefan Goemaere, Maria Rojeski

Publikováno v: Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research. 37(2)

Funder: NIHR Cambridge BRC; Id: http://dx.doi.org/10.13039/501100018956
Romosozumab monoclonal antibody treatment works by binding sclerostin and causing rapid stimulation of bone formation while decreasing bone resorption. The location and loca

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5aba7093d8d513c362a6e191dd1dbde9
https://pubmed.ncbi.nlm.nih.gov/34738660

Effects of Romosozumab Compared With Teriparatide on Bone Density and Mass at the Spine and Hip in Postmenopausal Women With Low Bone Mass

Autor: Carlos Mautalen, Michael A. Bolognese, Klaus Engelke, Harry K. Genant, Y.-C. Yang, Andreas Grauer, Chris Recknor, Cesar Libanati, Jacques P. Brown, Thomas Fuerst, Stefan Goemaere

Publikováno v: Journal of Bone and Mineral Research. 32:181-187

Romosozumab, a monoclonal antibody that binds sclerostin, has a dual effect on bone by increasing bone formation and reducing bone resorption, and thus has favorable effects in both aspects of bone volume regulation. In a phase 2 study, romosozumab i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::a6414d303c4e1b6607e2b8a4821b5752
https://doi.org/10.1002/jbmr.2932

High Prevalence of Sarcopenia in Women with Osteoporotic Fractures

Autor: Diana González, Beatriz Oliveri, Dolores Gómez Glorioso, ela Fernández, Alicia Bagur, Carlos Mautalen, Silvina Rosana Mastaglia

Publikováno v: CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET

The aim of the present study was to assess the prevalence of sarcopenia in women with osteopenia/osteoporosiswith or without fragility fractures.Patients and methods: 112 ambulatory women with osteopenia/osteporosis were included. Body composition wa

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd7f97117ddd079f8b51c998c29373be
http://www.esciencecentral.org/journals/high-prevalence-of-sarcopenia-in-women-with-osteoporotic-fractures-2329-9509-1000181.php?aid=78906

The effect of 8 or 5 years of denosumab treatment in postmenopausal women with osteoporosis: results from the FREEDOM Extension study

Autor: A. Wang, Carlos Mautalen, Salvatore Minisola, S. Papapoulos, C. Roux, Peter L. Lakatos, David L. Kendler, Nadia Daizadeh, S Jensen, Jean-Yves Reginster, Rachel B. Wagman, Edward Czerwiński, Henry G. Bone, Kurt Lippuner, E. M. Lewiecki, M Gavin, Edward Franek, C J F Lin, M. L. Brandi, Cesar Libanati

Publikováno v: Osteoporosis International
Osteoporosis International, 26(12), 2773-2783
Papapoulos, S; Lippuner, Kurt; Roux, C; Lin, C J F; Kendler, D L; Lewiecki, E M; Brandi, M L; Czerwiński, E; Franek, E; Lakatos, P; Mautalen, C; Minisola, S; Reginster, J Y; Jensen, S; Daizadeh, N S; Wang, A; Gavin, M; Libanati, C; Wagman, R B and Bone, H G (2015). The effect of 8 or 5 years of denosumab treatment in postmenopausal women with osteoporosis: results from the FREEDOM Extension study. Osteoporosis international, 26(12), pp. 2773-2783. Springer 10.1007/s00198-015-3234-7

Summary The FREEDOM study and its Extension provide long-term information about the effects of denosumab for the treatment of postmenopausal osteoporosis. Treatment for up to 8 years was associated with persistent reduction of bone turnover, continue

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc8829a8def16388007ebe69ace0cdd3
https://hdl.handle.net/1887/101286

Solar ultraviolet B radiation and photoproduction of vitamin D3 in central and southern areas of argentina

Autor: Marta G Ladizesky, Michael F. Holick, Zhiren Lu, Beatriz Oliveri, Nemesio San Roman, Carlos Mautalen, Susana Diaz

Publikováno v: Journal of Bone and Mineral Research. 10:545-549

The incidence of nutritional rickets in the southern part of Argentina is 8-12 times higher than in the rest of the country. Winter 25(OH)D serum levels in normal population of southern areas are lower than in central and northern areas. To elucidate

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::36b12c5813747ab5a9055c558bf341ab
https://doi.org/10.1002/jbmr.5650100406