Zobrazeno 1 - 10
of 622
pro vyhledávání: '"Carlos M. Ferrario"'
Autor:
Xiaoqiang Sun, Jing Cao, Zhe Chen, Yixi Liu, Jessica L. VonCannon, Heng Jie Cheng, Carlos M. Ferrario, Che Ping Cheng
Publikováno v:
Heliyon, Vol 9, Iss 7, Pp e17851- (2023)
Aims: Upregulation of Ca2+/calmodulin-dependent protein kinase II (CaMKII) contributes to the pathogenesis of cardiovascular disease, including hypertension. Transgenic rats expressing the human angiotensinogen gene [TGR (hAGT)L1623] are a new novel
Externí odkaz:
https://doaj.org/article/830f8fc8a989467d8a55f5682676329c
Autor:
Brittany Butts, Lee A. Goeddel, Jingyi Zheng, Betty Pat, Pamela Powell, James Mobley, Sarfaraz Ahmad, Chad Steele, David McGiffin, James E. Davies, James F. George, Spencer J. Melby, Carlos M. Ferrario, Louis J. Dell’Italia
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 10 (2023)
IntroductionChymase is a highly destructive serine protease rapidly neutralized in the circulation by protease inhibitors. Here we test whether pericardial fluid (PCF) chymase activation and other inflammatory biomarkers determine intensive care unit
Externí odkaz:
https://doaj.org/article/88a91f57392540e88245b8e9bdff9715
Autor:
Xiao Ma, Seethalakshmi R. Iyer, Xiaoyu Ma, Shawn H. Reginauld, Yang Chen, Shuchong Pan, Ye Zheng, Dante G. Moroni, Yue Yu, Lianwen Zhang, Valentina Cannone, Horng H. Chen, Carlos M. Ferrario, S. Jeson Sangaralingham, John C. Burnett
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 10, p 8547 (2023)
The natriuretic peptide system (NPS) and renin-angiotensin-aldosterone system (RAAS) function oppositely at multiple levels. While it has long been suspected that angiotensin II (ANGII) may directly suppress NPS activity, no clear evidence to date su
Externí odkaz:
https://doaj.org/article/a9048155f7c6498f83b9df87a4404ba5
Autor:
Brittany Butts, PhD, Mustafa I. Ahmed, MD, Navkaranbir S. Bajaj, MD, MPH, Pamela Cox Powell, MS, Betty Pat, PhD, Silvio Litovsky, MD, Himanshu Gupta, MD, Steven G. Lloyd, MD, Thomas S. Denney, PhD, Xiaoxia Zhang, PhD, Inmaculada Aban, PhD, Sakthivel Sadayappan, PhD, MBA, James W. McNamara, PhD, Michael J. Watson, PhD, Carlos M. Ferrario, MD, James F. Collawn, PhD, Clifton Lewis, MD, James E. Davies, MD, Louis J. Dell’Italia, MD
Publikováno v:
JACC: Basic to Translational Science, Vol 5, Iss 2, Pp 109-122 (2020)
Summary: Increasing left atrial (LA) size predicts outcomes in patients with isolated mitral regurgitation (MR). Chymase is plentiful in the human heart and affects extracellular matrix remodeling. Chymase activation correlates to LA fibrosis, LA enl
Externí odkaz:
https://doaj.org/article/8b2e10df0b604a758f656d121b3eff40
Autor:
Hao Wang, Jasmina Varagic, Sayaka Nagata, Neal D. Kon, Sarfaraz Ahmad, Jessica L. VonCannon, Kendra N. Wright, Xuming Sun, Dwight Deal, Leanne Groban, Carlos M. Ferrario
Publikováno v:
Data in Brief, Vol 31, Iss , Pp 105744- (2020)
The data presented here are related to the research article entitled “Differential expression of the angiotensin-(1-12) [Ang-(1-12)]/chymase axis in human atrial tissue [1]. We have showed that chymase gene transcripts, chymase activity, and immuno
Externí odkaz:
https://doaj.org/article/edd5cfa61e434332afa891d626b20d92
Autor:
Leanne Groban, Quang-Kim Tran, Carlos M. Ferrario, Xuming Sun, Che Ping Cheng, Dalane W. Kitzman, Hao Wang, Sarah H. Lindsey
Publikováno v:
Frontiers in Endocrinology, Vol 10 (2020)
The G Protein-Coupled Estrogen Receptor (GPER) is a novel membrane-bound receptor that mediates non-genomic actions of the primary female sex hormone 17β-estradiol. Studies over the past two decades have elucidated the beneficial actions of this rec
Externí odkaz:
https://doaj.org/article/383b10a099294d0a83703b09cf200964
Autor:
Carlos M. Ferrario, Jessica VonCannon, Sarfaraz Ahmad, Kendra N. Wright, Drew J. Roberts, Hao Wang, Tomohisa Yamashita, Leanne Groban, Che Ping Cheng, James F. Collawn, Louis J. Dell'Italia, Jasmina Varagic
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 6 (2019)
Angiotensin-(1-12) [Ang-(1-12)], an alternate substrate for tissue angiotensin II (Ang II) formation, underscores the importance of alternative renin-independent pathway(s) for the generation of angiotensins. Since renin enzymatic activity is species
Externí odkaz:
https://doaj.org/article/aa5a3eddcd864866b00cc3be183808a6
Autor:
Hao Wang, Xuming Sun, Jeff Chou, Marina Lin, Carlos M. Ferrario, Gisele Zapata-Sudo, Leanne Groban
Publikováno v:
Data in Brief, Vol 10, Iss C, Pp 465-473 (2017)
We previously showed that cardiomyocyte-specific G protein-coupled estrogen receptor (GPER) gene deletion leads to sex-specific adverse effects on cardiac structure and function; alterations which may be due to distinct differences in mitochondrial a
Externí odkaz:
https://doaj.org/article/25d888d49cfb4a97a1d94e73b4f861f9
Autor:
Ronald D. Smith, Hiroshi Yokoyama, David B. Averill, Lori Cooke, K. Bridget Brosnihan, Ernesto L. Schiffrin, Carlos M. Ferrario
Publikováno v:
Российский кардиологический журнал, Vol 0, Iss 5, Pp 83-90 (2010)
The VIOS (Vascular Improvement with Olmesartan medoxomil Study) study is a randomized, parallel study to determine the relative effects of suppressing the renin-angiotensin system (RAS) with the angiotensin receptor antagonist olmesartan medoxomil ve
Externí odkaz:
https://doaj.org/article/611289b7fd2a45b4873ec21967ded0f6
Autor:
Sarfaraz Ahmad, Kendra N. Wright, Jessica L. VonCannon, Carlos M. Ferrario, Mohammad S. Ola, Mayur Choudhary, Goldis Malek, Jenna R. Gustafson, Rebecca M. Sappington
Publikováno v:
Journal of Ocular Pharmacology and Therapeutics. 39:290-299