Gene expression patterns associated with Leishmania panamensis infection in macrophages from BALB/c and C57BL/6 mice.

Autor: Carlos M Restrepo, Alejandro Llanes, Lizzi Herrera, Esteban Ellis, Ricardo Lleonart, Patricia L Fernández

Publikováno v: PLoS Neglected Tropical Diseases, Vol 15, Iss 2, p e0009225 (2021)

Leishmania parasites can trigger different host immune responses that result in varying levels of disease severity. The C57BL/6 and BALB/c mouse strains are among the host models commonly used for characterizing the immunopathogenesis of Leishmania s

Externí odkaz: https://doaj.org/article/17d113ccc7ee432babccf8daf669ff43

Germline mutations of breast cancer susceptibility genes through expanded genetic analysis in unselected Colombian patients

Autor: Diana Carolina Sierra-Díaz, Adrien Morel, Dora Janeth Fonseca-Mendoza, Nora Contreras Bravo, Nicolas Molano-Gonzalez, Mariana Borras, Isabel Munevar, Mauricio Lema, Henry Idrobo, Daniela Trujillo, Norma Serrano, Ana Isabel Orduz, Diego Lopera, Jaime González, Gustavo Rojas, Paula Londono-De Los Ríos, Ray Manneh, Rodrigo Cabrera, Wilson Rubiano, Jairo de la Peña, María Catalina Quintero, William Mantilla, Carlos M. Restrepo

Publikováno v: Human Genomics, Vol 18, Iss 1, Pp 1-14 (2024)

Abstract Background In Colombia and worldwide, breast cancer (BC) is the most frequently diagnosed neoplasia and the leading cause of death from cancer among women. Studies predominantly involve hereditary and familial cases, demonstrating a gap in t

Externí odkaz: https://doaj.org/article/94dcc3407c7a4832a2bb89dbf14cae2d

A pseudopterane diterpene isolated from the octocoral Pseudopterogorgia acerosa inhibits the inflammatory response mediated by TLR-ligands and TNF-alpha in macrophages.

Autor: Yisett González, Deborah Doens, Ricardo Santamaría, Marla Ramos, Carlos M Restrepo, Luciana Barros de Arruda, Ricardo Lleonart, Marcelino Gutiérrez, Patricia L Fernández

Publikováno v: PLoS ONE, Vol 8, Iss 12, p e84107 (2013)

Several diterpenoids isolated from terrestrial and marine environments have been identified as important anti-inflammatory agents. Although considerable progress has been made in the area of anti-inflammatory treatment, the search for more effective

Externí odkaz: https://doaj.org/article/d838da88ab304b9ea0f587eebd02dfb7

Pharmacogenomic profile of actionable molecular variants related to drugs commonly used in anesthesia: WES analysis reveals new mutations

Autor: Juan Fernando Parada-Márquez, Nicolás David Maldonado-Rodriguez, Paula Triana-Fonseca, Nora Constanza Contreras-Bravo, Carlos Alberto Calderón-Ospina, Carlos M. Restrepo, Adrien Morel, Oscar Javier Ortega-Recalde, Daniel Felipe Silgado-Guzmán, Mariana Angulo-Aguado, Dora Janeth Fonseca-Mendoza

Publikováno v: Frontiers in Pharmacology, Vol 14 (2023)

Background: Genetic interindividual variability is associated with adverse drug reactions (ADRs) and affects the response to common drugs used in anesthesia. Despite their importance, these variants remain largely underexplored in Latin-American coun

Externí odkaz: https://doaj.org/article/769d31181bbe4c028ce1b9cd3b58da67

Building Programs to Eradicate Toxoplasmosis Part II: Education

Autor: Mariangela Soberón Felín, Kanix Wang, Aliya Moreira, Andrew Grose, Karen Leahy, Ying Zhou, Fatima Alibana Clouser, Maryam Siddiqui, Nicole Leong, Perpetua Goodall, Morgan Michalowski, Mahmoud Ismail, Monica Christmas, Stephen Schrantz, Zuleima Caballero, Ximena Norero, Dora Estripeaut, David Ellis, Catalina Raggi, Catherine Castro, Claudia Rengifo-Herrera, Davina Moossazadeh, Margarita Ramirez, Abhinav Pandey, Kevin Ashi, Samantha Dovgin, Ashtyn Dixon, Xuan Li, Ian Begeman, Sharon Heichman, Joseph Lykins, Delba Villalobos-Cerrud, Lorena Fabrega, José Luis Sanchez Montalvo, Connie Mendivil, Mario R. Quijada, Silvia Fernández-Pirla, Valli de La Guardia, Digna Wong, Mayrene Ladrón de Guevara, Carlos Flores, Jovanna Borace, Anabel García, Natividad Caballero, Maria Theresa Moreno de Saez, Michael Politis, Stephanie Ross, Mimansa Dogra, Vishan Dhamsania, Nicholas Graves, Marci Kirchberg, Kopal Mathur, Ashley Aue, Carlos M. Restrepo, Alejandro Llanes, German Guzman, Arturo Rebellon, Kenneth Boyer, Peter Heydemann, A. Gwendolyn Noble, Charles Swisher, Peter Rabiah, Shawn Withers, Teri Hull, David Frim, David McLone, Chunlei Su, Michael Blair, Paul Latkany, Ernest Mui, Daniel Vitor Vasconcelos-Santos, Alcibiades Villareal, Ambar Perez, Carlos Andrés Naranjo Galvis, Mónica Vargas Montes, Nestor Ivan Cardona Perez, Morgan Ramirez, Cy Chittenden, Edward Wang, Laura Lorena Garcia-López, Juliana Muñoz-Ortiz, Nicolás Rivera-Valdivia, María Cristina Bohorquez-Granados, Gabriela Castaño de-la-Torre, Guillermo Padrieu, Juan David Valencia Hernandez, Daniel Celis-Giraldo, John Alejandro Acosta Dávila, Elizabeth Torres, Manuela Mejia Oquendo, José Y. Arteaga-Rivera, Dan L. Nicolae, Andrey Rzhetsky, Nancy Roizen, Eileen Stillwaggon, Larry Sawers, Francois Peyron, Martine Wallon, Emanuelle Chapey, Pauline Levigne, Carmen Charter, Migdalia De Frias, Jose Montoya, Cindy Press, Raymund Ramirez, Despina Contopoulos-Ioannidis, Yvonne Maldonado, Oliver Liesenfeld, Carlos Gomez, Kelsey Wheeler, Samantha Zehar, James McAuley, Denis Limonne, Sandrine Houze, Sylvie Abraham, Raphael Piarroux, Vera Tesic, Kathleen Beavis, Ana Abeleda, Mari Sautter, Bouchra El Mansouri, Adlaoui El Bachir, Fatima Amarir, Kamal El Bissati, Ellen Holfels, Richard Penn, William Cohen, Alejandra de-la-Torre, Gabrielle Britton, Jorge Motta, Eduardo Ortega-Barria, Isabel Luz Romero, Paul Meier, Michael Grigg, Jorge Gómez-Marín, Jagannatha Rao Kosagisharaf, Xavier Sáez Llorens, Osvaldo Reyes, Rima McLeod

Publikováno v: Current Pediatrics Reports. 10:93-108

Purpose of Review Review work to create and evaluate educational materials that could serve as a primary prevention strategy to help both providers and patients in Panama, Colombia, and the USA reduce disease burden of Toxoplasma infections. Recent F

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::3d1ffea9261a1ef4e68e819db565487c
https://doi.org/10.1007/s40124-022-00267-y