Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Carlos M Opazo"'
Publikováno v:
Frontiers in Neuroscience, Vol 9 (2015)
Alpha-synuclein is a presynaptic protein expressed throughout the central nervous system, and it is the main component of Lewy bodies, one of the histopathological features of Parkinson’s disease (PD) which is a progressive and irreversible neurode
Externí odkaz:
https://doaj.org/article/193c35f959ff4b83854611622f5a222a
Autor:
Patricio A Castro, Alejandra eRamirez, Fernando J Sepulveda, Christian ePeters, Humberto eFierro, Javier eWaldron, Sandra eLuza, Jorge eFuentealba, Jose F Munoz, Giancarlo V De Ferrari, Ashley Ian Bush, Luis G Aguayo, Carlos M Opazo
Publikováno v:
Frontiers in Aging Neuroscience, Vol 6 (2014)
Extracellular and intracellular copper and zinc regulate synaptic activity and synaptic plasticity, which may impact brain functionality and human behavior. We have found that a metal coordinating molecule, Neocuproine, transiently increases free int
Externí odkaz:
https://doaj.org/article/c53c09d9e3f24722830e34d0b664d03c
Publikováno v:
Frontiers in Aging Neuroscience, Vol 6 (2014)
Copper is critical for the Central Nervous System (CNS) development and function. In particular, different studies have shown the effect of copper at brain synapses, where it inhibits Long Term Potentation (LTP) and receptor pharmacology. Paradoxical
Externí odkaz:
https://doaj.org/article/081ab00dc047408c92e1e3f2a00ee5d8
Autor:
Parsa Ravanfar, Samantha M. Loi, Warda T. Syeda, Tamsyn E. Van Rheenen, Ashley I. Bush, Patricia Desmond, Vanessa L. Cropley, Darius J. R. Lane, Carlos M. Opazo, Bradford A. Moffat, Dennis Velakoulis, Christos Pantelis
Publikováno v:
Frontiers in Neuroscience, Vol 15 (2021)
Iron has been increasingly implicated in the pathology of neurodegenerative diseases. In the past decade, development of the new magnetic resonance imaging technique, quantitative susceptibility mapping (QSM), has enabled for the more comprehensive i
Externí odkaz:
https://doaj.org/article/da5ed5350e9d4b79bd3d6b806c7b0886
Autor:
Amit Lotan, Sandra Luza, Carlos M. Opazo, Scott Ayton, Darius J. R. Lane, Serafino Mancuso, Avril Pereira, Suresh Sundram, Cynthia Shannon Weickert, Chad Bousman, Christos Pantelis, Ian P. Everall, Ashley I. Bush
Publikováno v:
Molecular Psychiatry.
Despite loss of grey matter volume and emergence of distinct cognitive deficits in young adults diagnosed with schizophrenia, current treatments for schizophrenia do not target disruptions in late maturational reshaping of the prefrontal cortex. Iron
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d5efc17a5a2c4c3fd9f770da458e401c
https://doi.org/10.1038/s41380-023-01979-3
https://doi.org/10.1038/s41380-023-01979-3
Autor:
Parsa Ravanfar, Warda T. Syeda, Mahesh Jayaram, R. Jarrett Rushmore, Bradford Moffat, Alexander P. Lin, Amanda E. Lyall, Antonia H. Merritt, Negin Yaghmaie, Liliana Laskaris, Sandra Luza, Carlos M. Opazo, Benny Liberg, M. Mallar Chakravarty, Gabriel A. Devenyi, Patricia Desmond, Vanessa L. Cropley, Nikos Makris, Martha E. Shenton, Ashley I. Bush, Dennis Velakoulis, Christos Pantelis
Publikováno v:
Schizophrenia. 8
Brain iron is central to dopaminergic neurotransmission, a key component in schizophrenia pathology. Iron can also generate oxidative stress, which is one proposed mechanism for gray matter volume reduction in schizophrenia. The role of brain iron in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e8cead1a0311b4a0b370d6232d03568
https://doi.org/10.1038/s41537-022-00293-1
https://doi.org/10.1038/s41537-022-00293-1
Novel Antidepressant-Like Properties of the Iron Chelator Deferiprone in a Mouse Model of Depression
Autor:
Volkan Uzungil, Harvey Tran, Connor Aitken, Carey Wilson, Carlos M. Opazo, Shanshan Li, Jennyfer M. Payet, Celeste H. Mawal, Ashley I. Bush, Matthew W. Hale, Anthony J. Hannan, Thibault Renoir
Publikováno v:
Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics. 19(5)
Depressed individuals who carry the short allele for the serotonin-transporter-linked promotor region of the gene are more vulnerable to stress and have reduced response to first-line antidepressants such as selective serotonin reuptake inhibitors. S
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7bf6746f5f627ee7d1d7714c02010c25
https://pubmed.ncbi.nlm.nih.gov/35861925
https://pubmed.ncbi.nlm.nih.gov/35861925
Autor:
Alessandro Alimonti, Michael Aschner, Terry Jo V. Bichell, Stephen C. Bondy, Valentina Borghesani, Aaron B. Bowman, Sonia Brescianini, David R. Brown, Maria C. Buscarinu, Ashley I. Bush, Bárbara R. Cardoso, Benedetta Cerasoli, Jingyuan Chen, James R. Connor, Lucio G. Costa, Peter J. Crouch, Melisa del Barrio, David C. Dorman, Peter Faller, Michela Ferraldeschi, Arianna Fornasiero, Andreas M. Grabrucker, Stefanie Grabrucker, Mark A. Greenough, Timothy C. Halbesma, Dominic J. Hare, Christelle Hureau, Hong Jiang, Katja M. Kanninen, Henna Konttinen, Katarína Lejavová, Frank W. Lewis, Wenjing Luo, Tarja Malm, Dinamene Marques dos Santos, Ana P. Marreilha dos Santos, Carlo Mattei, Rosella Mechelli, Alexandra I. Mot, Anne M. Nixon, Carlos M. Opazo, George Perry, Anna Pino, Germán Plascencia-Villa, Alejandra Ramírez Muñoz, Giovanni Ristori, Silvia Romano, Per M. Roos, Carlo Salustri, Marco Salvetti, Mariacristina Siotto, Rosanna Squitti, Maria A. Stazi, Peng Su, David Tétard, K. Grace Tipps, Mariacarla Ventriglia, Anthony R. White, Miguel José-Yacamán
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::04a3bc5cee762b5d7442ae6192a9cf00
https://doi.org/10.1016/b978-0-12-804562-6.00025-7
https://doi.org/10.1016/b978-0-12-804562-6.00025-7
