Zobrazeno 1 - 10
of 137
pro vyhledávání: '"Carlos Libertun"'
Publikováno v:
Neuroendocrinology. 112:998-1026
Introduction: The kisspeptin gene Kiss1 is expressed in two hypothalamic areas: anteroventral periventricular nucleus/periventricular nucleus (AVPV/PeN) and arcuate nucleus (ARC), and also in gonads. Several pieces of evidence suggests that gamma-ami
Autor:
Verónica Candela Martínez Allo, Alejandro D. Montaner, Carlos Libertun, Marta A. Toscano, Stefania Bianchi, Norma Alejandra Chasseing, Francisco Raúl Borzone, Sofía Gomez Bustillo, María Del R Lavignolle Heguy, Gabriel A. Rabinovich, Milena Massimino, María S. Bianchi, Victoria Lux-Lantos
Publikováno v:
Nucleic acid therapeutics. 31(2)
Type 1 diabetes occurs as a consequence of progressive autoimmune destruction of beta cells. A potential treatment for this disease should address the immune attack on beta cells and their preservation/regeneration. The objective of this study was to
Publikováno v:
American journal of physiology. Endocrinology and metabolism. 318(6)
Lack of GABA
Publikováno v:
CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
Lack of GABAB receptors in GABAB1 knockout mice decreases neonatal ARC kisspeptin 1 (Kiss1) expression in the arcuate nucleus of the hypothalamus (ARC) in females, which show impaired reproduction as adults. Our aim was to selectively impair GABAB si
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bcf77e24f010d49156cdb432ec6dfc31
https://journals.physiology.org/doi/abs/10.1152/ajpendo.00547.2019
https://journals.physiology.org/doi/abs/10.1152/ajpendo.00547.2019
Autor:
Carlos Libertun, Marina Fernandez, Eleonora Mariana Sorianello, Juan Manuel Riaño, Victoria Lux-Lantos
Publikováno v:
Journal of the Endocrine Society
Bisphenol A (BPA), a monomer of polycarbonate plastics, and Benzophenones (BPs), used as UV-filters, are endocrine disrupting chemicals (EDC) found in everyday products. Previously, we showed that the in-vitro exposure to BPA decreased Kiss-induced G
Autor:
Victoria Lux Lantos, Maria Silvia Bianchi, María Marta Bonaventura, Carlos Libertun, Alejandro D. Montaner, Ayelén Converti
Publikováno v:
Journal of the Endocrine Society
We have previously demonstrated that treatment with IMT504 promotes significant improvement in the diabetic condition in diverse animal models. We have also shown effects on gene expression on freshly isolated islets from diabetic IMT504-treated anim
Autor:
Carlos Libertun, Stefania Bianchi, Alejandro D. Montaner, María S. Bianchi, María Del R Lavignolle Heguy, Victoria Lux-Lantos
Publikováno v:
Journal of the Endocrine Society
We have shown that the immunomodulatory oligonucleotide IMT504 (IMT) induces a marked recovery of single-dose streptozotocin (STZ)-induced toxic diabetes in rats that correlates with early expression of progenitor cell markers but without altering im
Autor:
Marina Fernandez, Paula Arocena, Carlos Libertun, Camila Marigliano, Juan Riaño Gómez, Victoria Lux-Lantos
Publikováno v:
Journal of the Endocrine Society
Bisphenol A, (BPA), a component of polycarbonate plastics, and Benzophenones (BPs), UV filters, are endocrine disrupting chemicals (EDC). Previously we showed that the in vitro exposure to BPA decreased Kiss-induced GnRH expression in GN11 cells (Dr.
Publikováno v:
Journal of the Endocrine Society
We have previously shown that the administration of a GABAB antagonist (CGP55845) to neonatal BALB/C mice from postnatal day (PND) 2-6 significantly decreased arcuate nucleus (ARC) kisspeptin (Kiss1) expression in both sexes. Furthermore, this neonat
Publikováno v:
CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
Neuroendocrine control of reproduction involves the interplay of various factors that become active at some point along development. GnRH is the main neurohormone controlling reproduction and among the most important inputs modulating GnRH synthesis/