Zobrazeno 1 - 10
of 35
pro vyhledávání: '"Carlos Leomar Zani"'
Autor:
Rômulo José Soares-Bezerra, Natiele Carla da Silva Ferreira, Tânia Maria de Almeida Alves, Carlos Leomar Zani, Luiz Henrique Rosa, Andrea Surrage Calheiros, Cristiane Zanon de Souza, Julliana Alves Azeredo Miranda, Kátia Regina Ferreira Lima-Quaresma, Luiz Anastacio Alves, Válber da Silva Frutuoso
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 181, Iss , Pp 117657- (2024)
P2X7 is a purinergic receptor physiologically activated by extracellular ATP. Its activation induces proinflammatory responses, including cytokine release, reactive oxygen species formation, and cell death. Previous in vivo experimental models demons
Externí odkaz:
https://doaj.org/article/68c7ed5c39be4a35885e8f950d968d57
Autor:
Juliana Martins Ribeiro, Gisele André Baptista Canuto, Alisson Samuel Portes Caldeira, Ezequias Pessoa de Siqueira, Carlos Leomar Zani, Silvane Maria Fonseca Murta, Tânia Maria de Almeida Alves
Publikováno v:
Tropical Medicine and Infectious Disease, Vol 9, Iss 9, p 208 (2024)
Leishmaniasis is a complex disease caused by different species of Leishmania. To date, no vaccine for humans or ideal therapy has been developed owing to the limited efficacy and toxicity of available drugs, as well as the emergence of resistant stra
Externí odkaz:
https://doaj.org/article/85f915b7fd08438e9ac8dcd099ff92b0
Autor:
Suelen Queiroz Diniz, Maria Marta Figueiredo, Pedro Augusto Carvalho Costa, Olindo Assis Martins-Filho, Andrea Teixeira-Carvalho, Dhélio Batista Pereira, Mauro Shugiro Tada, Luis Carlos Crocco Afonso, Markus Kohlhoff, Carlos Leomar Zani, Ricardo Tostes Gazzinelli, Fabiano Oliveira, Lis Ribeiro Antonelli
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
BackgroundPlasmodium spp. infection triggers the production of inflammatory cytokines that are essential for parasite control, and conversely responsible for symptoms of malaria. Monocytes play a role in host defense against Plasmodium vivax infectio
Externí odkaz:
https://doaj.org/article/ed4f137f8034465b8ba22291bf0d4778
Autor:
Emerson de Castro Barbosa, Tânia Maria Almeida Alves, Markus Kohlhoff, Soraya Torres Gaze Jangola, Douglas Eduardo Valente Pires, Anna Carolina Cançado Figueiredo, Érica Alessandra Rocha Alves, Carlos Eduardo Calzavara-Silva, Marcos Sobral, Erna Geessien Kroon, Luiz Henrique Rosa, Carlos Leomar Zani, Jaquelline Germano de Oliveira
Publikováno v:
Virology Journal, Vol 19, Iss 1, Pp 1-15 (2022)
Abstract Background The worldwide epidemics of diseases as dengue and Zika have triggered an intense effort to repurpose drugs and search for novel antivirals to treat patients as no approved drugs for these diseases are currently available. Our aim
Externí odkaz:
https://doaj.org/article/4ca21516290e4a47a15004c79d0ef587
Autor:
Pedro Henrique Nascimento Aguiar, Núbia Monteiro Gonçalves Soares Fernandes, Carlos Leomar Zani, Marina Moraes Mourão
Publikováno v:
Parasites & Vectors, Vol 10, Iss 1, Pp 1-10 (2017)
Abstract Background Schistosoma mansoni is a trematode parasite that causes schistosomiasis, one of the most prevalent neglected tropical diseases, leading to the loss of 2.6 million disability-adjusted life years. Praziquantel is the only drug avail
Externí odkaz:
https://doaj.org/article/acec82d15ae54287b7cb6a81e44e5fe3
Autor:
Julia Penna Coutinho, Anna Caroline Campos Aguiar, Pierre Alexandre dos Santos, Joaquim Corsino Lima, Maria Gabrielle Lima Rocha, Carlos Leomar Zani, Tania Maria Almeida Alves, Antonio Euzebio Goulart Santana, Maria de Meneses Pereira, Antoniana Ursine Krettli
Publikováno v:
Memorias do Instituto Oswaldo Cruz, Vol 108, Iss 8, Pp 974-982 (2013)
Infusions of Aspidosperma nitidum (Apocynaceae) wood bark are used to treat fever and malaria in the Amazon Region. Several species of this family are known to possess indole alkaloids and other classes of secondary metabolites, whereas terpenoids, a
Externí odkaz:
https://doaj.org/article/deb8df461bf2480fadb22630c7d6c6d5
Autor:
Marina Azevêdo Souza, Susana Johann, Luciana Alves Rodrigues dos Santos Lima, Fernanda Fraga Campos, Isolda Castro Mendes, Heloisa Beraldo, Elaine Maria de Souza-Fagundes, Patrícia Silva Cisalpino, Carlos Augusto Rosa, Tânia Maria de Almeida Alves, Nívea Pereira de Sá, Carlos Leomar Zani
Publikováno v:
Memorias do Instituto Oswaldo Cruz, Vol 108, Iss 3, Pp 342-351 (2013)
Lapachol was chemically modified to obtain its thiosemicarbazone and semicarbazone derivatives. These compounds were tested for antimicrobial activity against several bacteria and fungi by the broth microdilution method. The thiosemicarbazone and sem
Externí odkaz:
https://doaj.org/article/8049d78a4fa546afb46f5a4cd64d77f8
Autor:
Gisell Apicela Soares, Renata Barbosa de Oliveira, Saulo Fernandes de Andrade, Ricardo José Alves, Carlos Leomar Zani, Elaine Maria de Souza-Fagundes
Publikováno v:
Molecules, Vol 15, Iss 1, Pp 12-26 (2009)
In our search for new anticancer therapies, some compounds synthesized in our lab were selected and their potential cytotoxic activity was evaluated in vitro against two cancer cells lines including a solid tumor (UACC-62, melanoma) and a human lymph
Externí odkaz:
https://doaj.org/article/57e9368881ef494b9f8da12cbe392956
Autor:
Fátima de Cássia Oliveira Gomes, Roberta Amália de Carvalho Araújo, Patrícia Silva Cisalpino, Elizabeth Spangler Andrade Moreira, Carlos Leomar Zani, Carlos Augusto Rosa
Publikováno v:
Brazilian Archives of Biology and Technology, Vol 52, Iss 2, Pp 449-455 (2009)
Two Saccharomyces cerevisiae strains were tested as the starter yeasts in a traditional cachaça distillery. The strains used were S. cerevisiae UFMG-A829, isolated from a cachaça fermentation process, and S. cerevisiae K1-V1116, obtained from the w
Externí odkaz:
https://doaj.org/article/8cf80e74599d4d47a39bac971c2954ea
Autor:
Betania Barros Cota, Luiz Henrique Rosa, Elaine Maria Souza Fagundes, Olindo Assis Martins-Filho, Rodrigo Correa-Oliveira, Alvaro José Romanha, Carlos Augusto Rosa, Carlos Leomar Zani
Publikováno v:
Memorias do Instituto Oswaldo Cruz, Vol 103, Iss 3, Pp 263-270 (2008)
The fungus Lentinus strigosus (Pegler 1983) (Polyporaceae, basidiomycete) was selected in a screen for inhibitory activity on Trypanosoma cruzi trypanothione reductase (TR). The crude extract of L. strigosus was able to completely inhibit TR at 20 µ
Externí odkaz:
https://doaj.org/article/65ce0fe5139c466ba4eb504eb7aeed1f