Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Carlos J. Nogueras‐Ortiz"'
Autor:
Kotb Abdelmohsen, Allison B. Herman, Angelica E. Carr, Charnae’ A. Henry‐Smith, Martina Rossi, Qiong Meng, Jen‐Hao Yang, Dimitrios Tsitsipatis, Alhassan Bangura, Rachel Munk, Jennifer L. Martindale, Carlos J. Nogueras‐Ortiz, Jon Hao, Yi Gong, Yie Liu, Chang‐Yi Cui, Lisa M. Hartnell, Nathan L. Price, Luigi Ferrucci, Dimitrios Kapogiannis, Rafael deCabo, Myriam Gorospe
Publikováno v:
Journal of Extracellular Biology, Vol 2, Iss 8, Pp n/a-n/a (2023)
Abstract Extracellular vesicles and particles (EVPs) are secreted by organs across the body into different circulatory systems, including the bloodstream, and reflect pathophysiologic conditions of the organ. However, the heterogeneity of EVPs in the
Externí odkaz:
https://doaj.org/article/656efe14d6fe4f1d8168af4c3c74e2f7
Autor:
Francheska Delgado-Peraza, Carlos J. Nogueras-Ortiz, Olga Volpert, Dong Liu, Edward J. Goetzl, Mark P. Mattson, Nigel H. Greig, Erez Eitan, Dimitrios Kapogiannis
Publikováno v:
Cells, Vol 10, Iss 5, p 993 (2021)
Circulating neuronal extracellular vesicles (NEVs) of Alzheimer’s disease (AD) patients show high Tau and β-amyloid (Aβ) levels, whereas their astrocytic EVs (AEVs) contain high complement levels. To validate EV proteins as AD biomarkers, we immu
Externí odkaz:
https://doaj.org/article/02ab44ba4e49498580cefada2c0d7ad5
Autor:
Carlos J. Nogueras-Ortiz, Vasiliki Mahairaki, Francheska Delgado-Peraza, Debamitra Das, Konstantinos Avgerinos, Erden Eren, Matthew Hentschel, Edward J. Goetzl, Mark P. Mattson, Dimitrios Kapogiannis
Publikováno v:
Cells, Vol 9, Iss 7, p 1618 (2020)
We have previously shown that blood astrocytic-origin extracellular vesicles (AEVs) from Alzheimer’s disease (AD) patients contain high complement levels. To test the hypothesis that circulating EVs from AD patients can induce complement-mediated n
Externí odkaz:
https://doaj.org/article/d0b3bbb841b04caf8b413f8964903427
Autor:
Carlos J Nogueras‐Ortiz, Erden Eren, Pamela Yao, Elizabeth Calzada, Christopher Dunn, Olga Volpert, Francheska Delgado‐Peraza, Maja Mustapic, Alexey Lyashkov, F Javier Rubio, Michael Vreones, Lesley Cheng, Yang You, Andrew F Hill, Tsuneya Ikezu, Erez Eitan, Edward J Goetzl, Dimitrios Kapogiannis
Publikováno v:
Journal of Extracellular Vesicles, Vol 13, Iss 6, Pp n/a-n/a (2024)
Abstract Isolation of neuron‐derived extracellular vesicles (NDEVs) with L1 Cell Adhesion Molecule (L1CAM)‐specific antibodies has been widely used to identify blood biomarkers of CNS disorders. However, full methodological validation requires de
Externí odkaz:
https://doaj.org/article/6df60f35215049c1aa20aedfca6fedc4
Publikováno v:
Frontiers in Neuroscience, Vol 7 (2014)
Molecular diagnostic tools with non-invasive properties that allow detection of pathological events in Alzheimer’s disease (AD) and other neurodegenerative tauopathies are essential for the development of therapeutics. Several diagnostic strategies
Externí odkaz:
https://doaj.org/article/119a4c2f4cac45cfae16b3bc77cf66ec